MCL coexpression mm9:2534

Phase1 CAGE Peaks

	Short description
Mm9::chr10:127986159..127986177,-	p1@Rpl41
Mm9::chr14:19103467..19103505,-	p1@Gm10224 p1@Gm4581 p1@LOC634785 p1@Rpl15
Mm9::chr2:32817221..32817234,+	p2@Rpl12

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0003735	structural constituent of ribosome	0.00178336575620057
GO:0005840	ribosome	0.00178336575620057
GO:0006412	translation	0.00661201460385156
GO:0030529	ribonucleoprotein complex	0.00661201460385156
GO:0009059	macromolecule biosynthetic process	0.0110478718420932
GO:0044249	cellular biosynthetic process	0.0159034677069647
GO:0009058	biosynthetic process	0.0249673521401245
GO:0005830	cytosolic ribosome (sensu Eukaryota)	0.0288907953959852
GO:0043232	intracellular non-membrane-bound organelle	0.0288907953959852
GO:0043228	non-membrane-bound organelle	0.0288907953959852
GO:0044445	cytosolic part	0.0404655777939637
GO:0032991	macromolecular complex	0.0404655777939637
GO:0005730	nucleolus	0.0404655777939637
GO:0042254	ribosome biogenesis and assembly	0.0435247295931946

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
motile cell	2.19e-12	54
animal cell	4.08e-11	115
eukaryotic cell	4.08e-11	115
connective tissue cell	5.07e-11	46
mesenchymal cell	5.07e-11	46
somatic cell	2.70e-10	118
hematopoietic cell	4.25e-10	32
hematopoietic oligopotent progenitor cell	4.25e-10	32
hematopoietic stem cell	4.25e-10	32
angioblastic mesenchymal cell	4.25e-10	32
hematopoietic multipotent progenitor cell	4.25e-10	32
stem cell	2.82e-08	97
lymphocyte	2.70e-07	13
common lymphoid progenitor	2.70e-07	13
somatic stem cell	4.48e-07	91
multi fate stem cell	4.48e-07	91
lymphoid lineage restricted progenitor cell	4.51e-07	12
T cell	5.96e-07	11
pro-T cell	5.96e-07	11
hematopoietic lineage restricted progenitor cell	9.01e-07	25

Uber Anatomy

Ontology term	p-value	n
connective tissue	5.07e-11	46

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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