MCL coexpression mm9:1492

Phase1 CAGE Peaks

	Short description
Mm9::chr10:107980160..107980166,+	p@chr10:107980160..107980166 +
Mm9::chr11:103799525..103799531,-	p5@Nsf
Mm9::chr6:95283986..95283988,-	p1@AY512915
Mm9::chr7:24170907..24170914,+	p1@Nlrp5
Mm9::chrX:140752342..140752344,+	p6@Alg13

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004577	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	0.0124910973538596
GO:0030259	lipid glycosylation	0.024978088645562
GO:0019905	syntaxin binding	0.0499233377932877
GO:0000149	SNARE binding	0.0499233377932877

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
female gonad	4.90e-53	3
external genitalia	3.95e-26	17
indifferent external genitalia	3.95e-26	17
indifferent gonad	3.95e-26	17
gonad	1.01e-24	18
gonad primordium	1.01e-24	18
female reproductive organ	1.53e-20	8
reproductive organ	9.72e-19	24
female reproductive system	2.30e-18	9
reproductive structure	2.36e-17	26
reproductive system	2.36e-17	26
female organism	3.43e-15	11
body cavity	2.12e-12	37
body cavity or lining	2.12e-12	37
body cavity precursor	4.33e-12	38
anatomical cavity	8.52e-12	39
seminiferous tubule of testis	6.19e-10	2
epithelium of male gonad	6.19e-10	2
epithelium of gonad	6.19e-10	2
epithelial cord	6.19e-10	2
sex cord	6.19e-10	2
testis sex cord	6.19e-10	2
genital ridge	6.19e-10	2
primitive sex cord of indifferent gonad	6.19e-10	2
coelomic epithelium	6.19e-10	2
anatomical space	2.96e-08	57
epididymis	4.77e-07	3
excretory tube	4.77e-07	3
mesonephric epithelium	4.77e-07	3
mesonephric tubule	4.77e-07	3
nephric duct	4.77e-07	3
kidney epithelium	4.77e-07	3
renal duct	4.77e-07	3
mesonephric duct	4.77e-07	3
somatic layer of lateral plate mesoderm	4.77e-07	3
pronephric duct	4.77e-07	3

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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