MCL coexpression mm9:528

Phase1 CAGE Peaks

	Short description
Mm9::chr11:51814250..51814277,-	p3@Ube2b
Mm9::chr11:5703272..5703283,+	p@chr11:5703272..5703283 +
Mm9::chr11:5703322..5703350,-	p@chr11:5703322..5703350 -
Mm9::chr11:5703561..5703572,-	p@chr11:5703561..5703572 -
Mm9::chr12:112216830..112216853,-	p4@Ankrd9
Mm9::chr16:8470856..8470900,+	p1@Mettl22
Mm9::chr19:18745302..18745339,+	p1@2410127L17Rik
Mm9::chr3:33919005..33919032,+	p1@Fxr1
Mm9::chr3:87710813..87710831,+	p5@Hdgf
Mm9::chr6:121160730..121160737,+	p4@Tuba8
Mm9::chr6:121160789..121160804,+	p3@Tuba8
Mm9::chr6:121160809..121160831,+	p1@Tuba8
Mm9::chr8:127386932..127386989,+	p1@Gnpat
Mm9::chr8:87339523..87339533,-	p@chr8:87339523..87339533 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0000226	microtubule cytoskeleton organization and biogenesis	0.0179285596888183
GO:0008611	ether lipid biosynthetic process	0.0179285596888183
GO:0016287	glycerone-phosphate O-acyltransferase activity	0.0179285596888183
GO:0046485	ether lipid metabolic process	0.0179285596888183
GO:0004083	bisphosphoglycerate phosphatase activity	0.0238929610542396
GO:0004082	bisphosphoglycerate mutase activity	0.0238929610542396
GO:0043034	costamere	0.0238929610542396
GO:0005782	peroxisomal matrix	0.0238929610542396
GO:0004619	phosphoglycerate mutase activity	0.0238929610542396
GO:0007288	sperm axoneme assembly	0.0238929610542396
GO:0035084	flagellum axoneme biogenesis	0.0238929610542396
GO:0016413	O-acetyltransferase activity	0.0238929610542396
GO:0007017	microtubule-based process	0.0255953936678224
GO:0035082	axoneme biogenesis	0.0255953936678224
GO:0009296	flagellum biogenesis	0.028662129411539
GO:0043064	flagellum organization and biogenesis	0.0301607463160448
GO:0044265	cellular macromolecule catabolic process	0.0301607463160448
GO:0046504	glycerol ether biosynthetic process	0.0301607463160448
GO:0045017	glycerolipid biosynthetic process	0.0301607463160448
GO:0001578	microtubule bundle formation	0.0306942858054484
GO:0016868	intramolecular transferase activity, phosphotransferases	0.0306942858054484
GO:0009057	macromolecule catabolic process	0.0431722467445519

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
primary circulatory organ	6.23e-07	18
heart	6.23e-07	18
primitive heart tube	6.23e-07	18
primary heart field	6.23e-07	18
anterior lateral plate mesoderm	6.23e-07	18
heart tube	6.23e-07	18
heart primordium	6.23e-07	18
cardiac mesoderm	6.23e-07	18
cardiogenic plate	6.23e-07	18
heart rudiment	6.23e-07	18

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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