MCL coexpression mm9:329

Phase1 CAGE Peaks

	Short description
Mm9::chr10:45008974..45009008,+	p2@Popdc3
Mm9::chr10:45009496..45009506,-	p3@ENSMUST00000162062
Mm9::chr13:12336352..12336379,-	p@chr13:12336352..12336379 -
Mm9::chr13:97205911..97205922,-	p1@Ankdd1b
Mm9::chr14:55608155..55608160,-	p@chr14:55608155..55608160 -
Mm9::chr17:71419994..71419996,+	p@chr17:71419994..71419996 +
Mm9::chr17:82130615..82130624,-	p@chr17:82130615..82130624 -
Mm9::chr18:42376580..42376599,-	p@chr18:42376580..42376599 -
Mm9::chr19:36188772..36188806,-	p@chr19:36188772..36188806 -
Mm9::chr2:25324643..25324713,-	p2@Ptgds
Mm9::chr3:142047969..142047976,-	p@chr3:142047969..142047976 -
Mm9::chr4:147360001..147360012,+	p1@Nppb
Mm9::chr4:147360152..147360158,+	p@chr4:147360152..147360158 +
Mm9::chr7:51734602..51734605,+	p@chr7:51734602..51734605 +
Mm9::chr8:15077718..15077725,+	p@chr8:15077718..15077725 +
Mm9::chr8:59801830..59801837,-	p@chr8:59801830..59801837 -
Mm9::chrX:139260164..139260200,+	p8@Tmem164
Mm9::chrX:139260210..139260233,+	p5@Tmem164
Mm9::chrX:139260241..139260259,+	p9@Tmem164
Mm9::chrX:154149104..154149128,+	p@chrX:154149104..154149128 +
Mm9::chrX:154149298..154149310,+	p@chrX:154149298..154149310 +
Mm9::chrX:154149464..154149473,+	p@chrX:154149464..154149473 +
Mm9::chrX:154149475..154149493,+	p@chrX:154149475..154149493 +
Mm9::chrX:154149497..154149508,+	p@chrX:154149497..154149508 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0022410	circadian sleep/wake cycle process	0.00953111277264864
GO:0042749	regulation of circadian sleep/wake cycle	0.00953111277264864
GO:0045187	regulation of circadian sleep/wake cycle, sleep	0.00953111277264864
GO:0050802	circadian sleep/wake cycle, sleep	0.00953111277264864
GO:0042745	circadian sleep/wake cycle	0.00953111277264864
GO:0042752	regulation of circadian rhythm	0.00953111277264864
GO:0048512	circadian behavior	0.01191193276837
GO:0030431	sleep	0.01191193276837
GO:0007622	rhythmic behavior	0.0138577408101196
GO:0046457	prostanoid biosynthetic process	0.0138577408101196
GO:0001516	prostaglandin biosynthetic process	0.0138577408101196
GO:0006693	prostaglandin metabolic process	0.0190465645434848
GO:0006692	prostanoid metabolic process	0.0190465645434848
GO:0046456	icosanoid biosynthetic process	0.0326217439820534
GO:0007623	circadian rhythm	0.034024540262353
GO:0006690	icosanoid metabolic process	0.034024540262353
GO:0003018	vascular process in circulatory system	0.034024540262353
GO:0035150	regulation of tube size	0.034024540262353
GO:0050880	regulation of blood vessel size	0.034024540262353

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
primary circulatory organ	3.12e-48	18
heart	3.12e-48	18
primitive heart tube	3.12e-48	18
primary heart field	3.12e-48	18
anterior lateral plate mesoderm	3.12e-48	18
heart tube	3.12e-48	18
heart primordium	3.12e-48	18
cardiac mesoderm	3.12e-48	18
cardiogenic plate	3.12e-48	18
heart rudiment	3.12e-48	18
cardiovascular system	3.52e-37	23
circulatory system	3.52e-37	23
splanchnic layer of lateral plate mesoderm	4.18e-25	33
compound organ	1.23e-18	43
epithelial tube	8.14e-17	47
structure with developmental contribution from neural crest	2.27e-08	92
lateral plate mesoderm	8.36e-08	87

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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