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MCL coexpression mm9:296

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:111432947..111432958,-p7@Glipr1
Mm9::chr10:111433688..111433699,-p@chr10:111433688..111433699
-
Mm9::chr10:119638520..119638539,-p4@Irak3
Mm9::chr11:100488216..100488234,+p@chr11:100488216..100488234
+
Mm9::chr11:16899725..16899729,-p@chr11:16899725..16899729
-
Mm9::chr11:59356203..59356228,+p2@Nlrp3
Mm9::chr11:59356232..59356249,+p3@Nlrp3
Mm9::chr11:59356250..59356277,+p4@Nlrp3
Mm9::chr11:67377978..67377989,+p@chr11:67377978..67377989
+
Mm9::chr12:32634451..32634474,+p@chr12:32634451..32634474
+
Mm9::chr12:70548695..70548699,+p@chr12:70548695..70548699
+
Mm9::chr13:51741105..51741116,+p@chr13:51741105..51741116
+
Mm9::chr14:28192677..28192680,+p@chr14:28192677..28192680
+
Mm9::chr14:28192716..28192779,+p@chr14:28192716..28192779
+
Mm9::chr14:28192780..28192801,+p@chr14:28192780..28192801
+
Mm9::chr14:28192831..28192847,+p@chr14:28192831..28192847
+
Mm9::chr14:28192852..28192868,+p@chr14:28192852..28192868
+
Mm9::chr1:52557492..52557495,+p@chr1:52557492..52557495
+
Mm9::chr2:102705692..102705695,-p@chr2:102705692..102705695
-
Mm9::chr2:127880698..127880703,-p@chr2:127880698..127880703
-
Mm9::chr2:127888836..127888845,+p@chr2:127888836..127888845
+
Mm9::chr2:13335211..13335224,-p@chr2:13335211..13335224
-
Mm9::chr3:83645477..83645490,-p2@Tlr2
Mm9::chr5:136722449..136722468,-p@chr5:136722449..136722468
-
Mm9::chr6:54767639..54767644,-p@chr6:54767639..54767644
-
Mm9::chr7:35841771..35841778,+p@chr7:35841771..35841778
+
Mm9::chrX:9048152..9048155,-p@chrX:9048152..9048155
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042892chloramphenicol transport0.00701254588286857
GO:0042891antibiotic transport0.00701254588286857
GO:0043244regulation of protein complex disassembly0.00701254588286857
GO:0002755MyD88-dependent toll-like receptor signaling pathway0.00841459401106075
GO:0002752cell surface pattern recognition receptor signaling pathway0.00841459401106075
GO:0002238response to molecule of fungal origin0.0105176662244004
GO:0002220innate immune response activating cell surface receptor signaling pathway0.0120195313783155
GO:0002224toll-like receptor signaling pathway0.0131456421358788
GO:0002221pattern recognition receptor signaling pathway0.0140181770504761
GO:0032760positive regulation of tumor necrosis factor production0.0140181770504761
GO:0002218activation of innate immune response0.0140181770504761
GO:0002758innate immune response-activating signal transduction0.0140181770504761
GO:0032680regulation of tumor necrosis factor production0.0140181770504761
GO:0045088regulation of innate immune response0.0140181770504761
GO:0045089positive regulation of innate immune response0.0140181770504761
GO:0009620response to fungus0.0151838620381715
GO:0043241protein complex disassembly0.0151838620381715
GO:0015893drug transport0.0151838620381715
GO:0032984macromolecular complex disassembly0.0154903787390998
GO:0032640tumor necrosis factor production0.0157661285899398
GO:0006915apoptosis0.0177806043039439
GO:0001819positive regulation of cytokine production0.0177806043039439
GO:0012501programmed cell death0.0177806043039439
GO:0008219cell death0.0177806043039439
GO:0016265death0.0177806043039439
GO:0022411cellular component disassembly0.0177806043039439
GO:0001817regulation of cytokine production0.0225045307870591
GO:0042493response to drug0.0225045307870591
GO:0002429immune response-activating cell surface receptor signaling pathway0.0231745390088081
GO:0002768immune response-regulating cell surface receptor signaling pathway0.0237995731722582
GO:0002757immune response-activating signal transduction0.024383985638227
GO:0002764immune response-regulating signal transduction0.0249315847224307
GO:0019221cytokine and chemokine mediated signaling pathway0.0286185847577295
GO:0048468cell development0.039830640220822
GO:0002253activation of immune response0.0460903485865604
GO:0005524ATP binding0.0462014597936259
GO:0032559adenyl ribonucleotide binding0.0462014597936259
GO:0045087innate immune response0.048186354519928
GO:0030554adenyl nucleotide binding0.048186354519928
GO:0050778positive regulation of immune response0.0493229335703659
GO:0002684positive regulation of immune system process0.0493229335703659
GO:0001816cytokine production0.0493229335703659



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Uber Anatomy
Ontology termp-valuen
bone marrow2.08e-1016
musculoskeletal system7.60e-0932
bone element1.76e-0822
skeletal element1.76e-0822
skeletal system1.76e-0822
connective tissue4.42e-0846
hemolymphoid system7.32e-0748
immune system7.32e-0748

Disease
Ontology termp-valuen
musculoskeletal system cancer8.02e-073
muscle cancer8.02e-073


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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