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Coexpression cluster:C3011

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Full id: C3011_Cardiac_Neutrophils_Smooth_parietal_occipital_middle_medial



Phase1 CAGE Peaks

Hg19::chr10:28884887..28884922,+p12@WAC
Hg19::chr16:89349579..89349590,-p31@ANKRD11
Hg19::chrX:102933456..102933469,-p15@MORF4L2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0031981nuclear lumen0.0452289844164347
GO:0031974membrane-enclosed lumen0.0452289844164347
GO:0043233organelle lumen0.0452289844164347
GO:0044428nuclear part0.0452289844164347



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism4.99e-20114
neural tube4.69e-1656
neural rod4.69e-1656
future spinal cord4.69e-1656
neural keel4.69e-1656
central nervous system6.34e-1481
regional part of nervous system8.42e-1453
regional part of brain8.42e-1453
brain4.59e-1368
future brain4.59e-1368
nervous system2.02e-1289
regional part of forebrain9.28e-1241
forebrain9.28e-1241
anterior neural tube9.28e-1241
future forebrain9.28e-1241
brain grey matter9.44e-1134
gray matter9.44e-1134
neurectoderm1.04e-0986
neural plate2.19e-0982
presumptive neural plate2.19e-0982
regional part of telencephalon3.34e-0932
telencephalon3.68e-0934
regional part of cerebral cortex1.92e-0822
cerebral hemisphere4.41e-0832
organ system subdivision6.42e-08223
structure with developmental contribution from neural crest6.50e-08132
cerebral cortex6.80e-0725
pallium6.80e-0725
neocortex7.40e-0720


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.