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MCL coexpression mm9:3442

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Phase1 CAGE Peaks

 Short description
Mm9::chr4:102243229..102243249,+p@chr4:102243229..102243249
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Mm9::chr4:102243268..102243284,+p@chr4:102243268..102243284
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Mm9::chr6:134742388..134742404,-p3@Dusp16


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042578phosphoric ester hydrolase activity0.00971803541665609
GO:00041153',5'-cyclic-AMP phosphodiesterase activity0.0108238311442
GO:0000188inactivation of MAPK activity0.0108238311442
GO:0016788hydrolase activity, acting on ester bonds0.0108238311442
GO:0043407negative regulation of MAP kinase activity0.0148951284823575
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity0.0162679755075525
GO:0004112cyclic-nucleotide phosphodiesterase activity0.0162679755075525
GO:0006469negative regulation of protein kinase activity0.0166379153774271
GO:0033673negative regulation of kinase activity0.0166379153774271
GO:0051348negative regulation of transferase activity0.0166379153774271
GO:0043086negative regulation of catalytic activity0.0187030868604814
GO:0043405regulation of MAP kinase activity0.0218757851855045
GO:0008081phosphoric diester hydrolase activity0.0218757851855045
GO:0016787hydrolase activity0.0327506438198464
GO:0000165MAPKKK cascade0.0327506438198464
GO:0045859regulation of protein kinase activity0.0327506438198464
GO:0043549regulation of kinase activity0.0327506438198464
GO:0051338regulation of transferase activity0.0327506438198464
GO:0007243protein kinase cascade0.0490044002385492
GO:0016791phosphoric monoester hydrolase activity0.0490044002385492



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
epithelial fold3.44e-0920
epithelial bud4.85e-0917
lung2.81e-0814
respiratory tube2.81e-0814
respiration organ2.81e-0814
pair of lungs2.81e-0814
lung primordium2.81e-0814
lung bud2.81e-0814
thoracic cavity element1.19e-0717
thoracic segment organ1.19e-0717
thoracic cavity1.19e-0717
thoracic segment of trunk1.19e-0717
respiratory primordium1.19e-0717
endoderm of foregut1.19e-0717


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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