MCL coexpression mm9:495

Phase1 CAGE Peaks

	Short description
Mm9::chr12:80660031..80660039,+	p@chr12:80660031..80660039 +
Mm9::chr15:99421081..99421098,+	p3@Aqp5
Mm9::chr19:30020231..30020242,+	p3@Il33
Mm9::chr19:30020272..30020289,+	p2@Il33
Mm9::chr19:47928736..47928764,+	p@chr19:47928736..47928764 +
Mm9::chr19:47929400..47929411,-	p@chr19:47929400..47929411 -
Mm9::chr19:47929512..47929537,+	p1@Gsto1
Mm9::chr19:47929697..47929715,+	p@chr19:47929697..47929715 +
Mm9::chr19:47932524..47932554,-	p@chr19:47932524..47932554 -
Mm9::chr1:175912973..175912979,-	p1@Ifi202b p1@LOC100044068
Mm9::chr2:122131407..122131416,-	p3@Duoxa1
Mm9::chr2:122131442..122131451,-	p2@Duoxa1
Mm9::chr5:91215126..91215131,+	p1@Cxcl3
Mm9::chr5:92416497..92416505,+	p1@Gm1045
Mm9::chr7:30980582..30980588,-	p16@Capns1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0009925	basal plasma membrane	0.0295973810546464
GO:0045178	basal part of cell	0.0295973810546464
GO:0015250	water channel activity	0.0295973810546464
GO:0005372	water transporter activity	0.0295973810546464
GO:0006833	water transport	0.0295973810546464
GO:0042044	fluid transport	0.0295973810546464
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	0.0322774391382923
GO:0005902	microvillus	0.0342835065633932
GO:0004364	glutathione transferase activity	0.0412027383397895

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
duct epithelial cell	4.24e-09	3
epithelial cell of tracheobronchial tree	4.24e-09	3
branched duct epithelial cell	4.24e-09	3
epithelial cell of lower respiratory tract	4.24e-09	3
respiratory epithelial cell	4.24e-09	3
tracheal epithelial cell	4.24e-09	3
tracheoblast	4.24e-09	3

Uber Anatomy

Ontology term	p-value	n
trachea	4.24e-09	3
respiratory airway	4.24e-09	3
tracheobronchial tree	4.24e-09	3
lower respiratory tract	4.24e-09	3
female reproductive system	4.66e-07	9

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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