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MCL coexpression mm9:251

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:101144309..101144320,+p11@Mgat4c
Mm9::chr11:116094025..116094042,+p@chr11:116094025..116094042
+
Mm9::chr11:34214757..34214786,+p1@Fam196b
Mm9::chr11:83223222..83223229,+p3@Rasl10b
Mm9::chr11:83223238..83223251,+p4@Rasl10b
Mm9::chr12:118392499..118392529,+p@chr12:118392499..118392529
+
Mm9::chr12:35591550..35591565,-p4@Hdac9
Mm9::chr12:35591579..35591625,-p3@Hdac9
Mm9::chr12:89963414..89963443,+p5@LOC100505240
p6@Nrxn3
Mm9::chr12:89964039..89964051,+p@chr12:89964039..89964051
+
Mm9::chr15:48623701..48623720,-p2@Csmd3
Mm9::chr15:76351357..76351367,+p@chr15:76351357..76351367
+
Mm9::chr16:11984249..11984263,+p4@Shisa9
Mm9::chr16:96689316..96689332,+p1@Pcp4
Mm9::chr1:72583270..72583295,+p@chr1:72583270..72583295
+
Mm9::chr2:144353262..144353273,-p5@6330439K17Rik
Mm9::chr2:22477768..22477780,+p10@Gad2
Mm9::chr2:22478013..22478038,+p5@Gad2
Mm9::chr2:22478051..22478112,+p1@Gad2
Mm9::chr2:22478133..22478157,+p3@Gad2
Mm9::chr2:22478162..22478173,+p9@Gad2
Mm9::chr2:70400169..70400180,+p5@Gad1
Mm9::chr2:70400189..70400200,+p4@Gad1
Mm9::chr2:70400204..70400265,+p1@Gad1
Mm9::chr2:70401608..70401629,+p11@Gad1
Mm9::chr2:81893447..81893468,+p2@Zfp804a
Mm9::chr3:107989328..107989342,+p3@Amigo1
Mm9::chr4:150513630..150513686,-p4@Camta1
Mm9::chr5:108798425..108798450,-p@chr5:108798425..108798450
-
Mm9::chr6:119280686..119280712,-p3@Lrtm2
Mm9::chr6:55401822..55401866,+p2@Adcyap1r1
Mm9::chr7:116925052..116925068,-p1@Nrip3
Mm9::chr8:10249334..10249366,+p@chr8:10249334..10249366
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004351glutamate decarboxylase activity0.000125101396125337
GO:0042136neurotransmitter biosynthetic process0.00485548292280011
GO:0016831carboxy-lyase activity0.0134108165512253
GO:0042133neurotransmitter metabolic process0.0173138834580098
GO:0016830carbon-carbon lyase activity0.0173138834580098
GO:0030170pyridoxal phosphate binding0.0199060448512584
GO:0019226transmission of nerve impulse0.0199060448512584
GO:0030424axon0.0288034153263468
GO:0007267cell-cell signaling0.0438793215454578
GO:0001505regulation of neurotransmitter levels0.0438793215454578
GO:0008454alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity0.0438793215454578
GO:0004999vasoactive intestinal polypeptide receptor activity0.0438793215454578



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)2.00e-1923
neuroblast (sensu Vertebrata)2.00e-1923
neuron5.70e-1233
neuronal stem cell5.70e-1233
neuroblast5.70e-1233
electrically signaling cell5.70e-1233
electrically responsive cell6.28e-0939
electrically active cell6.28e-0939
ectodermal cell1.05e-0744
neurectodermal cell1.05e-0744
neural cell2.04e-0743

Uber Anatomy
Ontology termp-valuen
neurectoderm7.15e-3464
neural plate7.15e-3464
presumptive neural plate7.15e-3464
regional part of nervous system2.90e-3354
neural tube6.61e-3152
neural rod6.61e-3152
future spinal cord6.61e-3152
neural keel6.61e-3152
ecto-epithelium1.86e-2973
pre-chordal neural plate1.92e-2849
central nervous system2.68e-2873
ectoderm-derived structure2.26e-2795
ectoderm2.26e-2795
presumptive ectoderm2.26e-2795
nervous system4.92e-2775
brain2.53e-2647
future brain2.53e-2647
gray matter9.07e-2634
regional part of brain3.44e-2546
anterior neural tube3.03e-2340
regional part of forebrain3.81e-2239
forebrain3.81e-2239
future forebrain3.81e-2239
brain grey matter3.43e-2129
regional part of telencephalon3.43e-2129
telencephalon3.43e-2129
structure with developmental contribution from neural crest1.88e-1992
cerebral cortex7.22e-1421
cerebral hemisphere7.22e-1421
pallium7.22e-1421
regional part of cerebral cortex8.03e-1217
occipital lobe2.10e-1010
visual cortex2.10e-1010
neocortex2.10e-1010
basal ganglion1.21e-088
nuclear complex of neuraxis1.21e-088
aggregate regional part of brain1.21e-088
collection of basal ganglia1.21e-088
cerebral subcortex1.21e-088
posterior neural tube5.57e-0812
chordal neural plate5.57e-0812
spinal cord9.73e-076
dorsal region element9.73e-076
dorsum9.73e-076


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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