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Coexpression cluster:C95

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Full id: C95_lung_aorta_trachea_penis_Alveolar_throat_endometrioid



Phase1 CAGE Peaks

Hg19::chr10:122740205..122740247,-p1@ENST00000414774
Hg19::chr10:23631651..23631656,+p@chr10:23631651..23631656
+
Hg19::chr10:64028596..64028611,-p3@RTKN2
Hg19::chr10:81315925..81315936,-p@chr10:81315925..81315936
-
Hg19::chr10:81315944..81315951,-p@chr10:81315944..81315951
-
Hg19::chr10:81315990..81316001,-p@chr10:81315990..81316001
-
Hg19::chr10:81316023..81316032,-p@chr10:81316023..81316032
-
Hg19::chr10:81316041..81316047,-p@chr10:81316041..81316047
-
Hg19::chr10:81316085..81316090,-p@chr10:81316085..81316090
-
Hg19::chr10:81316132..81316137,-p@chr10:81316132..81316137
-
Hg19::chr10:81316163..81316188,-p@chr10:81316163..81316188
-
Hg19::chr10:81316173..81316180,+p@chr10:81316173..81316180
+
Hg19::chr10:81316188..81316211,+p@chr10:81316188..81316211
+
Hg19::chr10:81316201..81316217,-p@chr10:81316201..81316217
-
Hg19::chr10:81316223..81316231,+p@chr10:81316223..81316231
+
Hg19::chr10:81316229..81316244,-p@chr10:81316229..81316244
-
Hg19::chr10:81316247..81316267,-p@chr10:81316247..81316267
-
Hg19::chr10:81316311..81316313,-p@chr10:81316311..81316313
-
Hg19::chr10:81316373..81316410,-p@chr10:81316373..81316410
-
Hg19::chr10:81316558..81316565,-p@chr10:81316558..81316565
-
Hg19::chr10:81316579..81316592,-p@chr10:81316579..81316592
-
Hg19::chr10:81316620..81316641,-p@chr10:81316620..81316641
-
Hg19::chr10:81316679..81316685,+p@chr10:81316679..81316685
+
Hg19::chr10:81316753..81316759,-p@chr10:81316753..81316759
-
Hg19::chr10:81316764..81316776,-p@chr10:81316764..81316776
-
Hg19::chr10:81316872..81316887,+p@chr10:81316872..81316887
+
Hg19::chr10:81316910..81316917,-p@chr10:81316910..81316917
-
Hg19::chr10:81316918..81316929,-p@chr10:81316918..81316929
-
Hg19::chr10:81316934..81316944,-p@chr10:81316934..81316944
-
Hg19::chr10:81320162..81320168,-p1@SFTPA1
p1@SFTPA2
Hg19::chr10:81320211..81320219,-p2@SFTPA1
p2@SFTPA2
Hg19::chr10:81370619..81370628,+p5@SFTPA1
Hg19::chr10:81370638..81370651,+p3@SFTPA1
Hg19::chr10:81370689..81370700,+p4@SFTPA1
Hg19::chr10:81374195..81374212,+p@chr10:81374195..81374212
+
Hg19::chr10:81374313..81374327,+p@chr10:81374313..81374327
+
Hg19::chr10:81374331..81374339,+p@chr10:81374331..81374339
+
Hg19::chr10:81374450..81374461,+p@chr10:81374450..81374461
+
Hg19::chr10:81374462..81374469,+p@chr10:81374462..81374469
+
Hg19::chr10:81374505..81374520,+p@chr10:81374505..81374520
+
Hg19::chr10:81374557..81374568,+p@chr10:81374557..81374568
+
Hg19::chr10:81374587..81374595,+p@chr10:81374587..81374595
+
Hg19::chr10:81374592..81374601,-p@chr10:81374592..81374601
-
Hg19::chr10:81374637..81374663,+p@chr10:81374637..81374663
+
Hg19::chr10:81374723..81374726,-p@chr10:81374723..81374726
-
Hg19::chr10:81374732..81374743,+p@chr10:81374732..81374743
+
Hg19::chr10:81374752..81374761,+p@chr10:81374752..81374761
+
Hg19::chr10:81374787..81374798,+p@chr10:81374787..81374798
+
Hg19::chr10:81374819..81374828,+p@chr10:81374819..81374828
+
Hg19::chr10:81374848..81374858,+p@chr10:81374848..81374858
+
Hg19::chr10:81708854..81708867,-p1@SFTPD
Hg19::chr11:62186498..62186515,+p1@SCGB1A1
Hg19::chr11:62189807..62189818,+p@chr11:62189807..62189818
+
Hg19::chr11:62189831..62189854,+p@chr11:62189831..62189854
+
Hg19::chr11:62190528..62190535,+p@chr11:62190528..62190535
+
Hg19::chr11:62190571..62190581,+p@chr11:62190571..62190581
+
Hg19::chr11:62190617..62190628,+p@chr11:62190617..62190628
+
Hg19::chr12:120151374..120151379,-p18@CIT
Hg19::chr12:26484826..26484836,-p@chr12:26484826..26484836
-
Hg19::chr12:53907724..53907729,+p1@ENST00000548347
p1@uc001sdx.2
Hg19::chr14:36967411..36967414,-p@chr14:36967411..36967414
-
Hg19::chr14:36983073..36983089,-p4@SFTA3
Hg19::chr14:36988564..36988601,-p7@NKX2-1
Hg19::chr14:36988691..36988705,-p3@ENST00000521945
Hg19::chr14:36990061..36990072,-p11@NKX2-1
Hg19::chr14:64676324..64676332,+p14@SYNE2
Hg19::chr15:66937016..66937035,+p@chr15:66937016..66937035
+
Hg19::chr15:66994523..66994541,+p5@SMAD6
Hg19::chr15:75017862..75017876,-p1@CYP1A1
Hg19::chr16:10590513..10590515,-p@chr16:10590513..10590515
-
Hg19::chr16:10674434..10674462,-p1@EMP2
Hg19::chr16:67399069..67399078,+p@chr16:67399069..67399078
+
Hg19::chr17:28523298..28523302,-p@chr17:28523298..28523302
-
Hg19::chr17:28562714..28562717,-p1@SLC6A4
Hg19::chr17:53800218..53800231,-p1@TMEM100
Hg19::chr17:53802864..53802896,-p@chr17:53802864..53802896
-
Hg19::chr17:53803029..53803034,-p@chr17:53803029..53803034
-
Hg19::chr17:7072385..7072388,+p@chr17:7072385..7072388
+
Hg19::chr19:41430150..41430163,+p1@CYP2B7P1
Hg19::chr19:50868888..50868902,-p1@NAPSA
Hg19::chr19:7606262..7606272,+p@chr19:7606262..7606272
+
Hg19::chr1:111822666..111822671,+p1@ENST00000369743
Hg19::chr1:43735646..43735660,+p2@TMEM125
Hg19::chr1:43735678..43735691,+p5@TMEM125
Hg19::chr1:78695343..78695353,+p2@ENST00000413519
Hg19::chr21:16116920..16116928,-p@chr21:16116920..16116928
-
Hg19::chr21:30126583..30126585,-p@chr21:30126583..30126585
-
Hg19::chr2:171600464..171600467,-p@chr2:171600464..171600467
-
Hg19::chr2:180610565..180610578,-p9@ZNF385B
Hg19::chr2:211117597..211117606,+p@chr2:211117597..211117606
+
Hg19::chr2:211118133..211118168,+p@chr2:211118133..211118168
+
Hg19::chr2:42305886..42305913,-p@chr2:42305886..42305913
-
Hg19::chr2:46229991..46230002,+p@chr2:46229991..46230002
+
Hg19::chr2:85884987..85884992,-p@chr2:85884987..85884992
-
Hg19::chr2:85885022..85885033,-p@chr2:85885022..85885033
-
Hg19::chr2:85885044..85885056,-p@chr2:85885044..85885056
-
Hg19::chr2:85885278..85885284,-p@chr2:85885278..85885284
-
Hg19::chr2:85885348..85885355,-p@chr2:85885348..85885355
-
Hg19::chr2:85885396..85885406,-p@chr2:85885396..85885406
-
Hg19::chr2:85885444..85885463,-p@chr2:85885444..85885463
-
Hg19::chr2:85885482..85885493,-p@chr2:85885482..85885493
-
Hg19::chr2:85885499..85885510,-p@chr2:85885499..85885510
-
Hg19::chr2:85885512..85885522,-p@chr2:85885512..85885522
-
Hg19::chr2:85885523..85885549,-p@chr2:85885523..85885549
-
Hg19::chr2:85885565..85885584,-p@chr2:85885565..85885584
-
Hg19::chr2:85886427..85886454,-p@chr2:85886427..85886454
-
Hg19::chr2:85886515..85886520,-p@chr2:85886515..85886520
-
Hg19::chr2:85886521..85886540,-p@chr2:85886521..85886540
-
Hg19::chr2:85886643..85886650,-p@chr2:85886643..85886650
-
Hg19::chr2:85886701..85886720,-p@chr2:85886701..85886720
-
Hg19::chr2:85886745..85886753,-p@chr2:85886745..85886753
-
Hg19::chr2:85888600..85888615,-p15@SFTPB
Hg19::chr2:85888627..85888660,-p6@SFTPB
Hg19::chr2:85889197..85889221,-p@chr2:85889197..85889221
-
Hg19::chr2:85889228..85889231,-p@chr2:85889228..85889231
-
Hg19::chr2:85889234..85889238,-p@chr2:85889234..85889238
-
Hg19::chr2:85890508..85890534,-p10@SFTPB
Hg19::chr2:85890821..85890836,-p14@SFTPB
Hg19::chr2:85890842..85890862,-p8@SFTPB
Hg19::chr2:85890883..85890893,-p17@SFTPB
Hg19::chr2:85890906..85890919,-p11@SFTPB
Hg19::chr2:85892457..85892493,-p@chr2:85892457..85892493
-
Hg19::chr2:85892774..85892795,-p9@SFTPB
Hg19::chr2:85892809..85892821,-p12@SFTPB
Hg19::chr2:85892828..85892855,-p7@SFTPB
Hg19::chr2:85892885..85892890,-p23@SFTPB
Hg19::chr2:85892901..85892909,-p20@SFTPB
Hg19::chr2:85892915..85892916,-p40@SFTPB
Hg19::chr2:85893058..85893063,-p35@SFTPB
Hg19::chr2:85893197..85893212,-p4@SFTPB
Hg19::chr2:85893272..85893280,-p18@SFTPB
Hg19::chr2:85893397..85893406,-p@chr2:85893397..85893406
-
Hg19::chr2:85893430..85893440,-p@chr2:85893430..85893440
-
Hg19::chr2:85893811..85893841,-p3@SFTPB
Hg19::chr2:85894261..85894307,-p5@SFTPB
Hg19::chr2:85894638..85894644,+p@chr2:85894638..85894644
+
Hg19::chr2:85894661..85894668,+p@chr2:85894661..85894668
+
Hg19::chr2:85894675..85894679,+p@chr2:85894675..85894679
+
Hg19::chr2:85894689..85894696,+p@chr2:85894689..85894696
+
Hg19::chr2:85894831..85894847,-p@chr2:85894831..85894847
-
Hg19::chr2:85894863..85894891,-p@chr2:85894863..85894891
-
Hg19::chr2:85938730..85938740,+p@chr2:85938730..85938740
+
Hg19::chr2:96331830..96331836,+p1@ENST00000425887
p1@uc002suw.1
Hg19::chr3:127109563..127109564,-p2@ENST00000488425
p2@uc003ejj.2
Hg19::chr3:137750301..137750312,+p@chr3:137750301..137750312
+
Hg19::chr4:25657354..25657366,+p3@SLC34A2
Hg19::chr4:25657412..25657422,-p@chr4:25657412..25657422
-
Hg19::chr4:25657465..25657481,+p1@SLC34A2
Hg19::chr4:25664140..25664151,+p@chr4:25664140..25664151
+
Hg19::chr4:25664152..25664169,+p@chr4:25664152..25664169
+
Hg19::chr4:25664174..25664190,-p@chr4:25664174..25664190
-
Hg19::chr4:25671333..25671346,+p5@SLC34A2
Hg19::chr4:25673247..25673269,+p@chr4:25673247..25673269
+
Hg19::chr4:25676147..25676159,+p@chr4:25676147..25676159
+
Hg19::chr4:25678518..25678558,+p7@SLC34A2
Hg19::chr4:25679218..25679229,+p@chr4:25679218..25679229
+
Hg19::chr4:25679338..25679349,+p@chr4:25679338..25679349
+
Hg19::chr4:25679353..25679363,+p@chr4:25679353..25679363
+
Hg19::chr4:25679470..25679504,+p@chr4:25679470..25679504
+
Hg19::chr4:25679783..25679794,+p@chr4:25679783..25679794
+
Hg19::chr5:149221692..149221707,+p@chr5:149221692..149221707
+
Hg19::chr5:149781399..149781435,-p@chr5:149781399..149781435
-
Hg19::chr5:59481438..59481445,-p70@PDE4D
Hg19::chr6:117746841..117746857,-p6@ROS1
Hg19::chr6:117746871..117746882,-p10@ROS1
Hg19::chr6:30899898..30899920,-p2@SFTA2
Hg19::chr6:30905205..30905225,-p@chr6:30905205..30905225
-
Hg19::chr6:32148852..32148862,-p@chr6:32148852..32148862
-
Hg19::chr6:32148869..32148878,-p@chr6:32148869..32148878
-
Hg19::chr6:32149013..32149018,-p@chr6:32149013..32149018
-
Hg19::chr6:32150144..32150162,-p@chr6:32150144..32150162
-
Hg19::chr6:32150643..32150658,-p4@AGER
Hg19::chr6:32150708..32150711,-p7@AGER
Hg19::chr6:41711116..41711125,-p@chr6:41711116..41711125
-
Hg19::chr7:116165709..116165737,+p7@CAV1
Hg19::chr7:30963395..30963409,+p8@AQP1
Hg19::chr7:30963544..30963579,+p4@AQP1
Hg19::chr8:17960308..17960314,-p@chr8:17960308..17960314
-
Hg19::chr8:22019303..22019321,+p1@SFTPC
Hg19::chr8:22020085..22020093,+p12@SFTPC
Hg19::chr8:22020106..22020124,+p5@SFTPC
Hg19::chr8:22020164..22020173,+p10@SFTPC
Hg19::chr8:22020196..22020202,+p13@SFTPC
Hg19::chr8:22020611..22020624,+p4@SFTPC
Hg19::chr8:22020647..22020661,+p6@SFTPC
Hg19::chr8:22020946..22020976,+p@chr8:22020946..22020976
+
Hg19::chr8:22020994..22020998,+p@chr8:22020994..22020998
+
Hg19::chr8:22021454..22021463,+p@chr8:22021454..22021463
+
Hg19::chr8:22021482..22021493,+p@chr8:22021482..22021493
+
Hg19::chr8:22021501..22021508,+p@chr8:22021501..22021508
+
Hg19::chr8:22021526..22021532,+p@chr8:22021526..22021532
+
Hg19::chr8:22021799..22021823,+p9@BMP1
Hg19::chr8:22021803..22021813,-p@chr8:22021803..22021813
-
Hg19::chr8:22021903..22021951,-p@chr8:22021903..22021951
-
Hg19::chr8:22021942..22021954,+p14@BMP1
Hg19::chrX:93772866..93772868,-p@chrX:93772866..93772868
-
Hg19::chrX:94084726..94084729,+p@chrX:94084726..94084729
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050828regulation of liquid surface tension3.30990684517979e-10
GO:0007585respiratory gaseous exchange7.77735944715749e-07
GO:0032501multicellular organismal process0.00156036647691286
GO:0042592homeostatic process0.00156036647691286
GO:0006817phosphate transport0.0100918815513624
GO:0005578proteinaceous extracellular matrix0.0112064398878544
GO:0005887integral to plasma membrane0.0112064398878544
GO:0031226intrinsic to plasma membrane0.0112064398878544
GO:0044421extracellular region part0.0126429836356155
GO:0030324lung development0.0126429836356155
GO:0065008regulation of biological quality0.0126429836356155
GO:0030323respiratory tube development0.0126429836356155
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen0.0126429836356155
GO:0048731system development0.0126429836356155
GO:0007275multicellular organismal development0.0126429836356155
GO:0006837serotonin transport0.0126429836356155
GO:0043129surfactant homeostasis0.0126429836356155
GO:0048875chemical homeostasis within a tissue0.0126429836356155
GO:0017026procollagen C-endopeptidase activity0.0126429836356155
GO:0015222serotonin transmembrane transporter activity0.0126429836356155
GO:0018894dibenzo-p-dioxin metabolic process0.0126429836356155
GO:0018904organic ether metabolic process0.0126429836356155
GO:0015698inorganic anion transport0.0126429836356155
GO:0048513organ development0.014878071801604
GO:0006820anion transport0.0187250466571659
GO:0042537benzene and derivative metabolic process0.0187250466571659
GO:0005076receptor signaling protein serine/threonine kinase signaling protein activity0.0187250466571659
GO:0021798forebrain dorsal/ventral pattern formation0.0187250466571659
GO:0005335serotonin:sodium symporter activity0.0187250466571659
GO:0030617transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity0.0187250466571659
GO:0005496steroid binding0.0202504632233741
GO:0048856anatomical structure development0.0228120322311609
GO:0009887organ morphogenesis0.0228120322311609
GO:0048286alveolus development0.0233987298973967
GO:0019834phospholipase A2 inhibitor activity0.0233987298973967
GO:0045085negative regulation of interleukin-2 biosynthetic process0.0233987298973967
GO:0048246macrophage chemotaxis0.0295467215956134
GO:0021871forebrain regionalization0.0295467215956134
GO:0035295tube development0.0301971429609436
GO:0000267cell fraction0.0303220959468354
GO:0015321sodium-dependent phosphate transmembrane transporter activity0.0323644717642325
GO:0005072transforming growth factor beta receptor, cytoplasmic mediator activity0.0323644717642325
GO:0008504monoamine transmembrane transporter activity0.0323644717642325
GO:0044459plasma membrane part0.0323644717642325
GO:0005071transmembrane receptor protein serine/threonine kinase signaling protein activity0.0365885426486297
GO:0015844monoamine transport0.0365885426486297
GO:00041153',5'-cyclic-AMP phosphodiesterase activity0.0400601955759071
GO:0008533astacin activity0.0400601955759071
GO:0030878thyroid gland development0.0400601955759071
GO:0005615extracellular space0.0415304615064712
GO:0032502developmental process0.0415304615064712
GO:0001504neurotransmitter uptake0.0415304615064712
GO:0042130negative regulation of T cell proliferation0.0415304615064712
GO:0005890sodium:potassium-exchanging ATPase complex0.0415304615064712
GO:0050766positive regulation of phagocytosis0.0450385551484781
GO:0007492endoderm development0.0450385551484781
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.0462703829101813
GO:0050764regulation of phagocytosis0.0466764296480633
GO:0006833water transport0.0466764296480633
GO:0050868negative regulation of T cell activation0.0466764296480633
GO:0042044fluid transport0.0466764296480633
GO:0005372water transporter activity0.0466764296480633
GO:0001502cartilage condensation0.0466764296480633
GO:0050672negative regulation of lymphocyte proliferation0.0466764296480633
GO:0032945negative regulation of mononuclear cell proliferation0.0466764296480633
GO:0008367bacterial binding0.0466764296480633
GO:0016021integral to membrane0.0493105837232668
GO:0005764lysosome0.0493105837232668
GO:0000323lytic vacuole0.0493105837232668
GO:0031224intrinsic to membrane0.0494672568566292



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
lower lobe of right lung1.84e-341
right lung lobe1.84e-341
lower lobe of lung1.84e-341
lobe of lung1.84e-341
right lung1.84e-341
lung2.38e-1422
respiratory tube2.38e-1422
respiration organ2.38e-1422
pair of lungs2.38e-1422
lung primordium2.38e-1422
lung bud2.38e-1422
thoracic cavity element1.48e-0934
thoracic cavity1.48e-0934
thoracic segment organ2.65e-0935
epithelial bud7.74e-0937
respiratory primordium1.27e-0838
endoderm of foregut1.27e-0838
epithelial fold4.22e-0747


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data