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Coexpression cluster:C508

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Full id: C508_Adipocyte_aorta_smooth_umbilical_bladder_hepatic_penis



Phase1 CAGE Peaks

Hg19::chr10:90695096..90695126,-p@chr10:90695096..90695126
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Hg19::chr10:90697836..90697854,+p@chr10:90697836..90697854
+
Hg19::chr10:90697845..90697865,-p@chr10:90697845..90697865
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Hg19::chr10:90697881..90697892,+p@chr10:90697881..90697892
+
Hg19::chr10:90697890..90697903,-p@chr10:90697890..90697903
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Hg19::chr10:90697895..90697934,+p@chr10:90697895..90697934
+
Hg19::chr10:90697913..90697941,-p@chr10:90697913..90697941
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Hg19::chr10:90697954..90697970,+p@chr10:90697954..90697970
+
Hg19::chr10:90699296..90699439,-p1@AK127229
Hg19::chr10:90701044..90701054,-p@chr10:90701044..90701054
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Hg19::chr10:90701565..90701581,-p@chr10:90701565..90701581
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Hg19::chr10:90701605..90701617,-p@chr10:90701605..90701617
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Hg19::chr10:90703608..90703675,-p@chr10:90703608..90703675
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Hg19::chr10:90707015..90707058,+p@chr10:90707015..90707058
+
Hg19::chr10:90707094..90707147,-p@chr10:90707094..90707147
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Hg19::chr10:90708582..90708630,-p3@ACTA2
Hg19::chr10:90708633..90708655,-p10@ACTA2
Hg19::chr10:90712520..90712536,-p1@ACTA2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision9.15e-17365
muscle tissue1.01e-1563
musculature1.01e-1563
musculature of body1.01e-1563
multi-tissue structure7.32e-15347
skeletal muscle tissue7.38e-1561
striated muscle tissue7.38e-1561
myotome7.38e-1561
somite1.05e-1483
paraxial mesoderm1.05e-1483
presomitic mesoderm1.05e-1483
presumptive segmental plate1.05e-1483
trunk paraxial mesoderm1.05e-1483
presumptive paraxial mesoderm1.05e-1483
dermomyotome3.05e-1470
adult organism4.68e-13115
multi-cellular organism5.40e-12659
trunk mesenchyme1.55e-11143
multilaminar epithelium1.20e-1082
anatomical cluster3.50e-09286
splanchnic layer of lateral plate mesoderm4.61e-0984
trunk1.06e-08216
epithelium1.44e-08309
cell layer1.58e-08312
anatomical system6.90e-08625
anatomical conduit7.43e-08241
primary circulatory organ8.86e-0827
anatomical group1.11e-07626
mesenchyme1.50e-07238
entire embryonic mesenchyme1.50e-07238
heart3.69e-0724
primitive heart tube3.69e-0724
primary heart field3.69e-0724
anterior lateral plate mesoderm3.69e-0724
heart tube3.69e-0724
heart primordium3.69e-0724
cardiac mesoderm3.69e-0724
cardiogenic plate3.69e-0724
heart rudiment3.69e-0724
unilaminar epithelium9.96e-07138


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.