MCL coexpression mm9:1425

Phase1 CAGE Peaks

	Short description
Mm9::chr1:173934582..173934589,-	p@chr1:173934582..173934589 -
Mm9::chr1:173934659..173934666,-	p@chr1:173934659..173934666 -
Mm9::chr1:173934671..173934684,-	p@chr1:173934671..173934684 -
Mm9::chr1:173957382..173957399,-	p2@Vangl2
Mm9::chr1:173957400..173957444,-	p1@Vangl2
Mm9::chr1:173987720..173987729,-	p1@Nhlh1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0035058	sensory cilium biogenesis	0.0137063192827999
GO:0007164	establishment of tissue polarity	0.0137063192827999
GO:0001736	establishment of planar polarity	0.0137063192827999
GO:0045197	establishment and/or maintenance of epithelial cell polarity	0.0137063192827999
GO:0045176	apical protein localization	0.0137063192827999
GO:0008105	asymmetric protein localization	0.0137063192827999
GO:0035088	establishment and/or maintenance of apical/basal cell polarity	0.0137063192827999
GO:0001738	morphogenesis of a polarized epithelium	0.0137063192827999
GO:0042384	cilium biogenesis	0.0139543778698986
GO:0001947	heart looping	0.0139543778698986
GO:0007163	establishment and/or maintenance of cell polarity	0.0217411228203974
GO:0003007	heart morphogenesis	0.0282255244932613
GO:0001843	neural tube closure	0.028373652194394
GO:0014020	primary neural tube formation	0.028373652194394
GO:0030031	cell projection biogenesis	0.028373652194394
GO:0016324	apical plasma membrane	0.028373652194394
GO:0001841	neural tube formation	0.028373652194394
GO:0001839	neural plate morphogenesis	0.028373652194394
GO:0001840	neural plate development	0.028373652194394
GO:0001838	embryonic epithelial tube formation	0.028373652194394
GO:0021915	neural tube development	0.0308083974695856
GO:0016331	morphogenesis of embryonic epithelium	0.0330202130454143
GO:0045177	apical part of cell	0.0333115541741164
GO:0002009	morphogenesis of an epithelium	0.0495929248956148
GO:0007275	multicellular organismal development	0.0495929248956148

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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