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MCL coexpression mm9:2619

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:100800621..100800633,-p5@Stat3
Mm9::chr11:100800641..100800669,-p3@Stat3
Mm9::chr2:75542032..75542048,-p@chr2:75542032..75542048
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042755eating behavior0.0168739385306525
GO:0001659thermoregulation0.0168739385306525
GO:0001754eye photoreceptor cell differentiation0.0168739385306525
GO:0046530photoreceptor cell differentiation0.0168739385306525
GO:0007259JAK-STAT cascade0.0168739385306525
GO:0006953acute-phase response0.0168739385306525
GO:0042593glucose homeostasis0.0168739385306525
GO:0033500carbohydrate homeostasis0.0168739385306525
GO:0007631feeding behavior0.0182131400013392
GO:0048592eye morphogenesis0.0197227852955679
GO:0019221cytokine and chemokine mediated signaling pathway0.0197227852955679
GO:0040014regulation of multicellular organism growth0.0208915429427126
GO:0035264multicellular organism growth0.0226222033048308
GO:0002526acute inflammatory response0.0265161891195968
GO:0001654eye development0.0334264687083402
GO:0040008regulation of growth0.0445954089738673
GO:0016563transcription activator activity0.0477520981547717
GO:0007423sensory organ development0.0477520981547717
GO:0046983protein dimerization activity0.0477520981547717
GO:0006954inflammatory response0.0477520981547717
GO:0048878chemical homeostasis0.0477520981547717
GO:0007243protein kinase cascade0.0479921108858818



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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