MCL coexpression mm9:1408

Phase1 CAGE Peaks

	Short description
Mm9::chr18:20716593..20716702,+	p1@Dsg2
Mm9::chr19:56623069..56623113,+	p3@Nhlrc2
Mm9::chr1:173367683..173367697,+	p2@F11r
Mm9::chr1:173367699..173367715,+	p1@F11r
Mm9::chr1:173367725..173367736,+	p3@F11r
Mm9::chr5:91069628..91069721,-	p1@Rassf6

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0043296	apical junction complex	0.00272330723700769
GO:0016327	apicolateral plasma membrane	0.00272330723700769
GO:0005911	intercellular junction	0.00504358679126346
GO:0030611	arsenate reductase activity	0.00998877227087679
GO:0030612	arsenate reductase (thioredoxin) activity	0.00998877227087679
GO:0030054	cell junction	0.0162270093294472
GO:0030057	desmosome	0.0166370106841642
GO:0022610	biological adhesion	0.0251358992688552
GO:0007155	cell adhesion	0.0251358992688552
GO:0030855	epithelial cell differentiation	0.0298925102388902
GO:0014704	intercalated disc	0.0339436361587461
GO:0005923	tight junction	0.0483017148894322

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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