MCL coexpression mm9:878

Phase1 CAGE Peaks

	Short description
Mm9::chr10:80289414..80289438,+	p1@Oaz1
Mm9::chr17:80333927..80333940,-	p@chr17:80333927..80333940 -
Mm9::chr2:121854322..121854334,+	p2@Gm9781
Mm9::chr2:157727184..157727213,+	p1@ENSMUST00000121302
Mm9::chr2:170110460..170110480,+	p1@ENSMUST00000118388
Mm9::chr3:95231497..95231510,+	p1@Gm4349
Mm9::chr3:96433842..96433878,+	p1@Rbm8a
Mm9::chr7:144562355..144562367,+	p@chr7:144562355..144562367 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008073	ornithine decarboxylase inhibitor activity	0.016159955885354
GO:0042979	ornithine decarboxylase regulator activity	0.016159955885354
GO:0006595	polyamine metabolic process	0.02584813721866
GO:0000184	mRNA catabolic process, nonsense-mediated decay	0.02584813721866
GO:0006402	mRNA catabolic process	0.0273101551622031
GO:0003729	mRNA binding	0.0273101551622031
GO:0006401	RNA catabolic process	0.0273101551622031
GO:0051028	mRNA transport	0.0273101551622031
GO:0050658	RNA transport	0.0273101551622031
GO:0051236	establishment of RNA localization	0.0273101551622031
GO:0050657	nucleic acid transport	0.0273101551622031
GO:0006403	RNA localization	0.0273101551622031
GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport	0.0273101551622031
GO:0006576	biogenic amine metabolic process	0.0331823158039291
GO:0006575	amino acid derivative metabolic process	0.0374068710784698

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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