MCL coexpression mm9:657

Phase1 CAGE Peaks

	Short description
Mm9::chr11:62416617..62416668,+	p1@Snord49b
Mm9::chr14:28192808..28192821,+	p@chr14:28192808..28192821 +
Mm9::chr15:97191697..97191715,+	p5@Fam113b
Mm9::chr16:49855202..49855213,+	p@chr16:49855202..49855213 +
Mm9::chr16:49855232..49855243,+	p7@Cd47
Mm9::chr2:163244850..163244902,-	p2@3230401D17Rik
Mm9::chr4:133430573..133430584,-	p7@Rps6ka1
Mm9::chr6:129300366..129300392,+	p4@Clec12a
Mm9::chr6:129300395..129300409,+	p5@Clec12a
Mm9::chr8:42502347..42502390,-	p2@Frg1
Mm9::chr9:108241379..108241401,+	p1@Gpx1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042254	ribosome biogenesis and assembly	0.0396803442286198
GO:0008228	opsonization	0.0396803442286198
GO:0022613	ribonucleoprotein complex biogenesis and assembly	0.0396803442286198
GO:0019903	protein phosphatase binding	0.0396803442286198
GO:0008631	induction of apoptosis by oxidative stress	0.0396803442286198
GO:0042744	hydrogen peroxide catabolic process	0.0396803442286198
GO:0019902	phosphatase binding	0.0396803442286198
GO:0042743	hydrogen peroxide metabolic process	0.0396803442286198
GO:0004602	glutathione peroxidase activity	0.0396803442286198
GO:0042542	response to hydrogen peroxide	0.0396803442286198
GO:0000302	response to reactive oxygen species	0.0488052468365194
GO:0050766	positive regulation of phagocytosis	0.0488052468365194
GO:0050764	regulation of phagocytosis	0.0488052468365194

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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