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MCL coexpression mm9:2546

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:21602020..21602045,+p8@Sgk1
Mm9::chr4:154719749..154719758,-p4@Prkcz
Mm9::chr9:81527119..81527171,-p@chr9:81527119..81527171
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0045179apical cortex0.00942285039103686
GO:0004700atypical protein kinase C activity0.00942285039103686
GO:0004674protein serine/threonine kinase activity0.0145566028350312
GO:0004672protein kinase activity0.0145566028350312
GO:0006468protein amino acid phosphorylation0.0145566028350312
GO:0016773phosphotransferase activity, alcohol group as acceptor0.0145566028350312
GO:0016310phosphorylation0.0145566028350312
GO:0004697protein kinase C activity0.0145566028350312
GO:0006793phosphorus metabolic process0.0145566028350312
GO:0006796phosphate metabolic process0.0145566028350312
GO:0001565phorbol ester receptor activity0.0145566028350312
GO:0016301kinase activity0.0153779896151013
GO:0016772transferase activity, transferring phosphorus-containing groups0.0185871248635674
GO:0044448cell cortex part0.0188322775505494
GO:0005524ATP binding0.0221164002125192
GO:0043687post-translational protein modification0.0221164002125192
GO:0032559adenyl ribonucleotide binding0.0221164002125192
GO:0019992diacylglycerol binding0.0221164002125192
GO:0030554adenyl nucleotide binding0.0221164002125192
GO:0005938cell cortex0.0221164002125192
GO:0006464protein modification process0.0249193206754661
GO:0043412biopolymer modification0.0249193206754661
GO:0000226microtubule cytoskeleton organization and biogenesis0.0249193206754661
GO:0032553ribonucleotide binding0.0249193206754661
GO:0032555purine ribonucleotide binding0.0249193206754661
GO:0005923tight junction0.0249519135053777
GO:0017076purine nucleotide binding0.0249519135053777
GO:0045177apical part of cell0.0258595973926225
GO:0016740transferase activity0.0264410244880735
GO:0043296apical junction complex0.0270002977994341
GO:0016327apicolateral plasma membrane0.0270002977994341
GO:0000166nucleotide binding0.0270002977994341
GO:0005911intercellular junction0.0426574809500271
GO:0005768endosome0.0455243430674482
GO:0007017microtubule-based process0.0471576119431688
GO:0044267cellular protein metabolic process0.0486033701908296
GO:0044260cellular macromolecule metabolic process0.0487909349677067



Relative expression of the co-expression cluster over median <br>Analyst:



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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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