MCL coexpression mm9:1701

Phase1 CAGE Peaks

	Short description
Mm9::chr16:77013945..77014020,+	p1@Usp25
Mm9::chr18:70727922..70728052,+	p1@Mbd2
Mm9::chr19:7416282..7416319,-	p3@Mark2
Mm9::chr5:138187181..138187192,+	p5@Tsc22d4
Mm9::chr7:28258801..28258838,+	p1@Sertad3

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0045180	basal cortex	0.0293983378253333
GO:0043283	biopolymer metabolic process	0.0293983378253333
GO:0008327	methyl-CpG binding	0.0293983378253333
GO:0035197	siRNA binding	0.03306950599807
GO:0042711	maternal behavior	0.0352702744957714
GO:0033057	reproductive behavior in a multicellular organism	0.0486286822378505
GO:0043170	macromolecule metabolic process	0.0486286822378505
GO:0045178	basal part of cell	0.0495716550066158

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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