MCL coexpression mm9:107
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0030318 | melanocyte differentiation | 0.0245230399177696 |
| GO:0050931 | pigment cell differentiation | 0.0245230399177696 |
| GO:0007275 | multicellular organismal development | 0.0245230399177696 |
| GO:0001755 | neural crest cell migration | 0.0245230399177696 |
| GO:0007422 | peripheral nervous system development | 0.0245230399177696 |
| GO:0001701 | in utero embryonic development | 0.0245230399177696 |
| GO:0048066 | pigmentation during development | 0.0245230399177696 |
| GO:0014032 | neural crest cell development | 0.0245230399177696 |
| GO:0014033 | neural crest cell differentiation | 0.0245230399177696 |
| GO:0022610 | biological adhesion | 0.0245230399177696 |
| GO:0007155 | cell adhesion | 0.0245230399177696 |
| GO:0048731 | system development | 0.0245230399177696 |
| GO:0014031 | mesenchymal cell development | 0.0245230399177696 |
| GO:0048762 | mesenchymal cell differentiation | 0.0245230399177696 |
| GO:0048869 | cellular developmental process | 0.0245230399177696 |
| GO:0030154 | cell differentiation | 0.0245230399177696 |
| GO:0001829 | trophectodermal cell differentiation | 0.0245230399177696 |
| GO:0050431 | transforming growth factor beta binding | 0.0245230399177696 |
| GO:0001600 | endothelin-B receptor activity | 0.0245230399177696 |
| GO:0030971 | receptor tyrosine kinase binding | 0.0245230399177696 |
| GO:0007497 | posterior midgut development | 0.0245230399177696 |
| GO:0048646 | anatomical structure formation | 0.0343096837245323 |
| GO:0005667 | transcription factor complex | 0.0343096837245323 |
| GO:0032502 | developmental process | 0.0343096837245323 |
| GO:0001568 | blood vessel development | 0.0343096837245323 |
| GO:0001944 | vasculature development | 0.0343096837245323 |
| GO:0016361 | activin receptor activity, type I | 0.0343096837245323 |
| GO:0017002 | activin receptor activity | 0.0343096837245323 |
| GO:0004962 | endothelin receptor activity | 0.0343096837245323 |
| GO:0007494 | midgut development | 0.0343096837245323 |
| GO:0048856 | anatomical structure development | 0.0345956572711971 |
| GO:0009790 | embryonic development | 0.0345956572711971 |
| GO:0005201 | extracellular matrix structural constituent | 0.0345956572711971 |
| GO:0048468 | cell development | 0.0354617629518457 |
| GO:0043009 | chordate embryonic development | 0.0355391392346548 |
| GO:0009792 | embryonic development ending in birth or egg hatching | 0.0358877002660932 |
| GO:0005025 | transforming growth factor beta receptor activity, type I | 0.039562073686022 |
| GO:0048484 | enteric nervous system development | 0.039562073686022 |
| GO:0043149 | stress fiber formation | 0.039562073686022 |
| GO:0019199 | transmembrane receptor protein kinase activity | 0.0419181546907758 |
| GO:0048469 | cell maturation | 0.0419966051958706 |
| GO:0044451 | nucleoplasm part | 0.0461431632330263 |
| GO:0060037 | pharyngeal system development | 0.0463915369030656 |
| GO:0043277 | apoptotic cell clearance | 0.0463915369030656 |
| GO:0007167 | enzyme linked receptor protein signaling pathway | 0.0463915369030656 |
| GO:0051179 | localization | 0.0476151749188097 |
| GO:0016477 | cell migration | 0.0476151749188097 |
| GO:0005654 | nucleoplasm | 0.0476151749188097 |
| GO:0048041 | focal adhesion formation | 0.0494938416044267 |
| GO:0005606 | laminin-1 complex | 0.0494938416044267 |
| GO:0001825 | blastocyst formation | 0.0494938416044267 |
| GO:0021700 | developmental maturation | 0.0494938416044267 |
| GO:0044420 | extracellular matrix part | 0.0495976462553279 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
| Ontology term | p-value | n |
|---|
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
{{{tfbs_overrepresentation_jaspar}}} |
