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Coexpression cluster:C2957

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Full id: C2957_medial_occipital_Neurons_amygdala_brain_duodenum_temporal



Phase1 CAGE Peaks

Hg19::chrX:153667431..153667445,+p@chrX:153667431..153667445
+
Hg19::chrX:153669457..153669479,+p9@GDI1
Hg19::chrX:153669960..153670004,+p6@GDI1
Hg19::chrX:153670019..153670061,+p11@GDI1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.00e-2757
neural rod1.00e-2757
future spinal cord1.00e-2757
neural keel1.00e-2757
central nervous system6.60e-2682
regional part of brain7.22e-2359
regional part of nervous system1.75e-2294
nervous system1.75e-2294
brain1.81e-2169
future brain1.81e-2169
anterior neural tube4.38e-2142
regional part of forebrain4.52e-2141
forebrain4.52e-2141
future forebrain4.52e-2141
neurectoderm7.73e-1990
gray matter2.86e-1834
brain grey matter2.86e-1834
telencephalon3.75e-1834
neural plate4.17e-1886
presumptive neural plate4.17e-1886
regional part of telencephalon1.23e-1733
cerebral hemisphere4.09e-1732
cerebral cortex1.90e-1325
pallium1.90e-1325
pre-chordal neural plate1.93e-1361
ectoderm2.15e-13173
presumptive ectoderm2.15e-13173
regional part of cerebral cortex4.34e-1322
adult organism6.82e-13115
ectoderm-derived structure1.02e-12169
neocortex6.42e-1220
head4.12e-11123
anterior region of body1.78e-10129
craniocervical region1.78e-10129
tube3.28e-10194
anatomical conduit1.83e-08241
posterior neural tube8.59e-0815
chordal neural plate8.59e-0815
multi-cellular organism8.70e-08659
organism subdivision2.43e-07365


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.