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Coexpression cluster:C2210

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Full id: C2210_medial_occipital_duodenum_spinal_hippocampus_cerebral_optic



Phase1 CAGE Peaks

Hg19::chr12:50291331..50291372,-p6@FAIM2
Hg19::chr19:6495958..6495977,-p@chr19:6495958..6495977
-
Hg19::chr4:89618393..89618411,-p5@NAP1L5
Hg19::chrX:102470619..102470632,+p2@BEX4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube6.30e-3057
neural rod6.30e-3057
future spinal cord6.30e-3057
neural keel6.30e-3057
central nervous system8.34e-2882
regional part of nervous system3.12e-2694
nervous system3.12e-2694
adult organism3.81e-26115
regional part of forebrain2.65e-2541
forebrain2.65e-2541
future forebrain2.65e-2541
anterior neural tube4.05e-2442
regional part of brain5.56e-2459
brain1.61e-2369
future brain1.61e-2369
gray matter8.67e-2334
brain grey matter8.67e-2334
telencephalon1.33e-2234
neurectoderm3.81e-2290
neural plate4.73e-2286
presumptive neural plate4.73e-2286
regional part of telencephalon5.39e-2233
cerebral hemisphere2.92e-2132
regional part of cerebral cortex5.08e-1722
cerebral cortex1.48e-1625
pallium1.48e-1625
pre-chordal neural plate1.73e-1661
neocortex1.41e-1520
ectoderm1.65e-14173
presumptive ectoderm1.65e-14173
head1.96e-14123
anterior region of body2.48e-14129
craniocervical region2.48e-14129
ectoderm-derived structure3.44e-14169
nucleus of brain1.03e-079
neural nucleus1.03e-079
basal ganglion1.14e-079
nuclear complex of neuraxis1.14e-079
aggregate regional part of brain1.14e-079
collection of basal ganglia1.14e-079
cerebral subcortex1.14e-079
posterior neural tube4.53e-0715
chordal neural plate4.53e-0715
temporal lobe7.19e-077


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.