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Coexpression cluster:C4167

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Full id: C4167_parietal_temporal_occipital_duodenum_putamen_pituitary_neuroectodermal



Phase1 CAGE Peaks

Hg19::chr2:197791441..197791525,-p1@PGAP1
Hg19::chrX:73439688..73439692,-p@chrX:73439688..73439692
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Hg19::chrX:73513353..73513414,-p1@FTX


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0015798myo-inositol transport0.00294360061226893
GO:0015791polyol transport0.00367950076533615
GO:0006505GPI anchor metabolic process0.0152086031633895
GO:0031227intrinsic to endoplasmic reticulum membrane0.0224449546685506
GO:0030384phosphoinositide metabolic process0.0235488048981514
GO:0006650glycerophospholipid metabolic process0.0247753051532635
GO:0031300intrinsic to organelle membrane0.0319590923617769
GO:0006644phospholipid metabolic process0.0395546332273637
GO:0004518nuclease activity0.0400329683268574
GO:0006643membrane lipid metabolic process0.0400329683268574



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.17e-35115
central nervous system2.68e-3282
regional part of nervous system3.84e-3294
nervous system3.84e-3294
neural tube1.07e-2957
neural rod1.07e-2957
future spinal cord1.07e-2957
neural keel1.07e-2957
brain2.46e-2769
future brain2.46e-2769
regional part of brain6.22e-2759
anterior neural tube4.20e-2542
regional part of forebrain5.80e-2541
forebrain5.80e-2541
future forebrain5.80e-2541
telencephalon4.49e-2134
gray matter5.43e-2134
brain grey matter5.43e-2134
neurectoderm1.04e-2090
regional part of telencephalon1.89e-2033
cerebral hemisphere5.65e-2032
neural plate4.27e-1986
presumptive neural plate4.27e-1986
ectoderm6.72e-19173
presumptive ectoderm6.72e-19173
ectoderm-derived structure1.68e-17169
anterior region of body3.49e-17129
craniocervical region3.49e-17129
head2.90e-16123
cerebral cortex1.04e-1525
pallium1.04e-1525
regional part of cerebral cortex2.84e-1522
pre-chordal neural plate1.61e-1461
neocortex5.41e-1420
basal ganglion6.24e-079
nuclear complex of neuraxis6.24e-079
aggregate regional part of brain6.24e-079
collection of basal ganglia6.24e-079
cerebral subcortex6.24e-079
nucleus of brain9.60e-079
neural nucleus9.60e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.