UBERON:0000042
From FANTOM5_SSTAR
| Name: | serous membrane | ||
|---|---|---|---|
| Definition: | "a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]." [Wikipedia:Serosa, Wikipedia:Serous_membrane] | ||
| Xrefs: |
| ||
| Synonyms: |
"serosa" EXACT [] "tunica serosa" EXACT [FMA:9581] "wall of serous sac" EXACT [FMA:9581] | ||
| Comments: | TODO - add generic membrane parent? TODO - split into serosa and serous membrane? | ||
| Subset: |
uberon_slim vertebrate_core |
200px-Ens.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0004120(mesoderm-derived structure),UBERON:0004457(cavity lining) |
|---|---|
| develops_from: | UBERON:0000926(mesoderm) |
Children
| is a: | UBERON:0002095 (mesentery),UBERON:0002358 (peritoneum),UBERON:0004782 (gastrointestinal system serosa),UBERON:0007616 (layer of synovial tissue) |
|---|---|
| part of: | UBERON:0001136 (mesothelium) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10276-104E6
- 10304-104H7
- 10332-105B8
- 10441-106E9 (synovial sarcoma cell line:HS-SY-II)
- 11291-117A4 (Synoviocyte, donor1)
- 11329-117E6 (Preadipocyte - omental, donor2)
- 11368-117I9 (Synoviocyte, donor2)
- 11403-118D8 (Preadipocyte - omental, donor3)
- 11440-118H9 (Synoviocyte, donor3)
- 11468-119C1 (Preadipocyte - omental, donor1)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000042 (serous membrane), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 1.36e-86 | FFCP PHASE1:Mm9::chr19:45161527..45161539,+#_303f27f7cfa44691c3838396829dc151 | p@chr19:45161527..45161539, + |
| 1.36e-86 | FFCP PHASE2:Mm9::chr19:45161527..45161539,+#_303f27f7cfa44691c3838396829dc151 | p@chr19:45161527..45161539, + |
| 4.43e-82 | FFCP PHASE2:Hg19::chr18:20122740..20122747,+#_121731cc5e62db355e2842fb42f972fb | p@chr18:20122740..20122747, + |
| 4.43e-82 | FFCP PHASE1:Hg19::chr18:20122740..20122747,+#_121731cc5e62db355e2842fb42f972fb | p@chr18:20122740..20122747, + |
| 1.01e-74 | FFCP PHASE2:Mm9::chr19:45224323..45224368,+#_e744702754e0f03a1ce7d82b9b07a9a2 | p@chr19:45224323..45224368, + |
| 1.01e-74 | FFCP PHASE1:Mm9::chr19:45224323..45224368,+#_e744702754e0f03a1ce7d82b9b07a9a2 | p@chr19:45224323..45224368, + |
| 2.48e-72 | FFCP PHASE2:Mm9::chr13:108293519..108293533,-#_ce49d330969032f5f6ca71e8c3685405 | p@chr13:108293519..108293533, - |
| 2.48e-72 | FFCP PHASE1:Mm9::chr13:108293519..108293533,-#_ce49d330969032f5f6ca71e8c3685405 | p@chr13:108293519..108293533, - |
| 1.35e-65 | FFCP PHASE1:Mm9::chr19:42116119..42116133,+#_4e66c9581eb1236208ee7751ba251af5 | p@chr19:42116119..42116133, + |
| 1.35e-65 | FFCP PHASE2:Mm9::chr19:42116119..42116133,+#_4e66c9581eb1236208ee7751ba251af5 | p@chr19:42116119..42116133, + |
| 4.13e-51 | FFCP PHASE1:Hg19::chr15:39087815..39087824,-#_0c43ca5b227c13312fa7bbdaf52f2c45 | p@chr15:39087815..39087824, - |
| 4.13e-51 | FFCP PHASE2:Hg19::chr15:39087815..39087824,-#_0c43ca5b227c13312fa7bbdaf52f2c45 | p@chr15:39087815..39087824, - |
| 5.59e-50 | FFCP PHASE1:Hg19::chr7:73484112..73484119,+#_7530e55ac7881c3e13a34e0c0a739216 | p43@ELN |
| 5.59e-50 | FFCP PHASE2:Hg19::chr7:73484112..73484119,+#_7530e55ac7881c3e13a34e0c0a739216 | p43@ELN |
| 1.09e-46 | FFCP PHASE2:Mm9::chr19:45224993..45225027,-#_a313da0598156203fb783a1f070e4d3f | p@chr19:45224993..45225027, - |
| 1.09e-46 | FFCP PHASE1:Mm9::chr19:45224993..45225027,-#_a313da0598156203fb783a1f070e4d3f | p@chr19:45224993..45225027, - |
| 1.86e-46 | FFCP PHASE2:Mm9::chr2:124537273..124537278,-#_9c9e5c3a442c2e8f8e44b5f3c9ba8994 | p@chr2:124537273..124537278, - |
| 1.86e-46 | FFCP PHASE1:Mm9::chr2:124537273..124537278,-#_9c9e5c3a442c2e8f8e44b5f3c9ba8994 | p@chr2:124537273..124537278, - |
| 2.72e-42 | FFCP PHASE1:Hg19::chr19:18718172..18718197,+#_1df9f78f998b54979cdb83dbf6276149 | p@chr19:18718172..18718197, + |
| 2.72e-42 | FFCP PHASE2:Hg19::chr19:18718172..18718197,+#_1df9f78f998b54979cdb83dbf6276149 | p@chr19:18718172..18718197, + |
| 8.75e-42 | FFCP PHASE2:Hg19::chr19:18898355..18898369,+#_ca91e78746f2af5a7e0d449c5a9cadf0 | p@chr19:18898355..18898369, + |
| 8.75e-42 | FFCP PHASE1:Hg19::chr19:18900805..18900820,-#_ca91e78746f2af5a7e0d449c5a9cadf0 | p@chr19:18900805..18900820, - |
| 8.75e-42 | FFCP PHASE2:Hg19::chr19:18900805..18900820,-#_ca91e78746f2af5a7e0d449c5a9cadf0 | p@chr19:18900805..18900820, - |
| 8.75e-42 | FFCP PHASE1:Hg19::chr19:18898355..18898369,+#_ca91e78746f2af5a7e0d449c5a9cadf0 | p@chr19:18898355..18898369, + |
| 2.56e-41 | FFCP PHASE1:Hg19::chr19:18898324..18898353,+#_d13e4d0acf1c51b80d47678c25ed0b09 | p@chr19:18898324..18898353, + |
| 2.56e-41 | FFCP PHASE2:Hg19::chr19:18898324..18898353,+#_d13e4d0acf1c51b80d47678c25ed0b09 | p@chr19:18898324..18898353, + |
| 9.04e-41 | FFCP PHASE1:Hg19::chr7:37947092..37947121,+#_8e4310ad25b30fb8a84dbf62a78dfbea | p2@CU691333 |
| 9.04e-41 | FFCP PHASE2:Hg19::chr7:37947092..37947121,+#_8e4310ad25b30fb8a84dbf62a78dfbea | p2@CU691333 |
| 1.54e-40 | FFCP PHASE1:Hg19::chr7:37947182..37947207,-#_735b13fe61f3e6fa039411b519f47ceb | p@chr7:37947182..37947207, - |
| 1.54e-40 | FFCP PHASE2:Hg19::chr7:37947182..37947207,-#_735b13fe61f3e6fa039411b519f47ceb | p@chr7:37947182..37947207, - |
| 2.32e-40 | FFCP PHASE1:Hg19::chr12:8814772..8814786,-#_809e87696e6f29a09d5c5a81caa9460f | p13@MFAP5 |
| 2.32e-40 | FFCP PHASE2:Hg19::chr12:8814772..8814786,-#_809e87696e6f29a09d5c5a81caa9460f | p13@MFAP5 |
| 1.42e-39 | FFCP PHASE1:Hg19::chr19:18900031..18900054,+#_78c640f9af5ce221b03ad23880d73590 | p@chr19:18900031..18900054, + |
| 1.42e-39 | FFCP PHASE2:Hg19::chr19:18900031..18900054,+#_78c640f9af5ce221b03ad23880d73590 | p@chr19:18900031..18900054, + |
| 1.92e-39 | FFCP PHASE1:Mm9::chr10:24966689..24966692,-#_309da9850b933d3070740dff5bbd09b2 | p@chr10:24966689..24966692, - |
| 1.92e-39 | FFCP PHASE2:Mm9::chr10:24966689..24966692,-#_309da9850b933d3070740dff5bbd09b2 | p@chr10:24966689..24966692, - |
| 2.2e-39 | FFCP PHASE1:Hg19::chr19:18899114..18899135,-#_ee47bd37576183ccab7e65a681d33ded | p@chr19:18899114..18899135, - |
| 2.2e-39 | FFCP PHASE2:Hg19::chr19:18899114..18899135,-#_ee47bd37576183ccab7e65a681d33ded | p@chr19:18899114..18899135, - |
| 2.54e-39 | FFCP PHASE2:Hg19::chr19:18896512..18896527,-#_5c31f3cdf53dcd4baff50621dbc585bf | p@chr19:18896512..18896527, - |
| 2.54e-39 | FFCP PHASE1:Hg19::chr19:18896512..18896527,-#_5c31f3cdf53dcd4baff50621dbc585bf | p@chr19:18896512..18896527, - |
| 1.63e-38 | FFCP PHASE2:Hg19::chr15:81242954..81242966,+#_31d0d2a426aa11ea9432acc9c416cc5d | p@chr15:81242954..81242966, + |
| 1.63e-38 | FFCP PHASE1:Hg19::chr15:81242954..81242966,+#_31d0d2a426aa11ea9432acc9c416cc5d | p@chr15:81242954..81242966, + |
| 1.32e-37 | FFCP PHASE1:Hg19::chr19:18893611..18893635,-#_931da52399d885f9f85314b0ad7bc246 | p1@AK094919 |
| 1.32e-37 | FFCP PHASE2:Hg19::chr15:81225699..81225710,+#_931da52399d885f9f85314b0ad7bc246 | p26@KIAA1199 |
| 1.32e-37 | FFCP PHASE2:Hg19::chr19:18893611..18893635,-#_931da52399d885f9f85314b0ad7bc246 | p1@AK094919 |
| 1.32e-37 | FFCP PHASE1:Hg19::chr15:81225699..81225710,+#_931da52399d885f9f85314b0ad7bc246 | p26@KIAA1199 |
| 1.32e-37 | FFCP PHASE2:Hg19::chr4:112437251..112437278,+#_931da52399d885f9f85314b0ad7bc246 | p@chr4:112437251..112437278, + |
| 1.32e-37 | FFCP PHASE1:Hg19::chr4:112437251..112437278,+#_931da52399d885f9f85314b0ad7bc246 | p@chr4:112437251..112437278, + |
| 1.34e-37 | FFCP PHASE1:Hg19::chr19:18896642..18896656,-#_b2521a4670b8565702baccbf22a4f69a | p@chr19:18896642..18896656, - |
| 1.34e-37 | FFCP PHASE2:Hg19::chr19:18896642..18896656,-#_b2521a4670b8565702baccbf22a4f69a | p@chr19:18896642..18896656, - |
| 5.84e-37 | FFCP PHASE2:Hg19::chr19:18899991..18900007,-#_c6079f6504e681854c12ac5b4ec20fd8 | p@chr19:18899991..18900007, - |
| 5.84e-37 | FFCP PHASE1:Hg19::chr19:18899991..18900007,-#_c6079f6504e681854c12ac5b4ec20fd8 | p@chr19:18899991..18900007, - |
| 7.41e-37 | FFCP PHASE1:Hg19::chr19:18899076..18899101,-#_d236ee679dfe105eebd2684f5e3a300f | p@chr19:18899076..18899101, - |
| 7.41e-37 | FFCP PHASE2:Hg19::chr19:18899076..18899101,-#_d236ee679dfe105eebd2684f5e3a300f | p@chr19:18899076..18899101, - |
| 3.25e-36 | FFCP PHASE1:Hg19::chr19:18900836..18900848,-#_00848f5cff408e59262fc27281a84e35 | p@chr19:18900836..18900848, - |
| 3.25e-36 | FFCP PHASE2:Hg19::chr19:18900836..18900848,-#_00848f5cff408e59262fc27281a84e35 | p@chr19:18900836..18900848, - |
| 1.87e-35 | FFCP PHASE1:Hg19::chr19:18899504..18899530,-#_50e91a2bbf69b820cfe80d8cfd495510 | p@chr19:18899504..18899530, - |
| 1.87e-35 | FFCP PHASE2:Hg19::chr19:18899504..18899530,-#_50e91a2bbf69b820cfe80d8cfd495510 | p@chr19:18899504..18899530, - |
| 5.37e-35 | FFCP PHASE1:Hg19::chr3:13670704..13670708,+#_3a5c1fc8a1f87022d891d5fa140fd8e6 | p@chr3:13670704..13670708, + |
| 5.37e-35 | FFCP PHASE2:Hg19::chr3:13670704..13670708,+#_3a5c1fc8a1f87022d891d5fa140fd8e6 | p@chr3:13670704..13670708, + |
| 5.88e-35 | FFCP PHASE2:Hg19::chr19:18709357..18709369,-#_37e1c61035513a01116006db16219b1c | p@chr19:18709357..18709369, - |
| 5.88e-35 | FFCP PHASE1:Hg19::chr19:18709357..18709369,-#_37e1c61035513a01116006db16219b1c | p@chr19:18709357..18709369, - |
| 6.77e-35 | FFCP PHASE2:Hg19::chr7:37947202..37947228,+#_a46526c74b296ae79e120f05d758acd4 | p1@CU691333 |
| 6.77e-35 | FFCP PHASE1:Hg19::chr7:37947202..37947228,+#_a46526c74b296ae79e120f05d758acd4 | p1@CU691333 |
| 1.12e-34 | FFCP PHASE2:Hg19::chr10:105428550..105428555,-#_d5b4adfe223457d1a848cbc5ce89baef | p25@SH3PXD2A |
| 1.12e-34 | FFCP PHASE1:Hg19::chr10:105428550..105428555,-#_d5b4adfe223457d1a848cbc5ce89baef | p25@SH3PXD2A |
| 1.41e-34 | FFCP PHASE1:Hg19::chr19:18893717..18893745,+#_238405261a80cecfd16a1767da0f8c33 | p@chr19:18893717..18893745, + |
| 1.41e-34 | FFCP PHASE2:Hg19::chr19:18893717..18893745,+#_238405261a80cecfd16a1767da0f8c33 | p@chr19:18893717..18893745, + |
| 1.64e-34 | FFCP PHASE1:Hg19::chr19:18899247..18899272,-#_01ddac0c064648f747f50eed9c7d7b75 | p@chr19:18899247..18899272, - |
| 1.64e-34 | FFCP PHASE2:Hg19::chr19:18899247..18899272,-#_01ddac0c064648f747f50eed9c7d7b75 | p@chr19:18899247..18899272, - |
| 1.9e-34 | FFCP PHASE2:Hg19::chr15:81242191..81242201,+#_f252265d1183fdabc3a8a83ce53bd37e | p19@KIAA1199 |
| 1.9e-34 | FFCP PHASE1:Hg19::chr15:81242191..81242201,+#_f252265d1183fdabc3a8a83ce53bd37e | p19@KIAA1199 |
| 2.01e-34 | FFCP PHASE2:Hg19::chr19:18896862..18896874,-#_ba1a3509a7df5d6a167d90e445c9aa0e | p@chr19:18896862..18896874, - |
| 2.01e-34 | FFCP PHASE1:Hg19::chr19:18896862..18896874,-#_ba1a3509a7df5d6a167d90e445c9aa0e | p@chr19:18896862..18896874, - |
| 2.68e-34 | FFCP PHASE2:Hg19::chr15:26342114..26342124,+#_4b5c96cd8ce518891111202c564a01ef | p@chr15:26342114..26342124, + |
| 2.68e-34 | FFCP PHASE1:Hg19::chr15:26342114..26342124,+#_4b5c96cd8ce518891111202c564a01ef | p@chr15:26342114..26342124, + |
| 2.85e-34 | FFCP PHASE1:Hg19::chr19:18897375..18897390,-#_b0298f18fcc04af60b7f11804d599284 | p4@COMP |
| 2.85e-34 | FFCP PHASE2:Hg19::chr19:18897375..18897390,-#_b0298f18fcc04af60b7f11804d599284 | p4@COMP |
| 4.28e-34 | FFCP PHASE1:Mm9::chr14:47707200..47707205,+#_ffbd357a86e0e1d8ec675ac44ef96a01 | p@chr14:47707200..47707205, + |
| 4.28e-34 | FFCP PHASE2:Mm9::chr14:47707200..47707205,+#_ffbd357a86e0e1d8ec675ac44ef96a01 | p@chr14:47707200..47707205, + |
| 5.19e-34 | FFCP PHASE1:Mm9::chr4:59686875..59686885,+#_bc811a081a063e91f0a5bfda9f5b857c | p@chr4:59686875..59686885, + |
| 5.19e-34 | FFCP PHASE2:Mm9::chr4:59686875..59686885,+#_bc811a081a063e91f0a5bfda9f5b857c | p@chr4:59686875..59686885, + |
| 5.98e-34 | FFCP PHASE2:Hg19::chr21:28820892..28820899,-#_1005718978f668bc236ef98d97bf066a | p4@ENST00000420186, p4@uc002ymh.2 |
| 5.98e-34 | FFCP PHASE2:Hg19::chr9:127269488..127269495,-#_1005718978f668bc236ef98d97bf066a | p5@NR5A1 |
| 5.98e-34 | FFCP PHASE2:Hg19::chr9:79894790..79894797,+#_1005718978f668bc236ef98d97bf066a | p10@VPS13A |
| 5.98e-34 | FFCP PHASE1:Hg19::chr9:127269434..127269438,-#_1005718978f668bc236ef98d97bf066a | p8@NR5A1 |
| 5.98e-34 | FFCP PHASE1:Hg19::chr21:28820941..28820952,-#_1005718978f668bc236ef98d97bf066a | p2@ENST00000420186, p2@uc002ymh.2 |
| 5.98e-34 | FFCP PHASE1:Hg19::chr11:56859638..56859643,-#_1005718978f668bc236ef98d97bf066a | p@chr11:56859638..56859643, - |
| 5.98e-34 | FFCP PHASE2:Hg19::chr8:22436248..22436259,+#_1005718978f668bc236ef98d97bf066a | p11@PDLIM2 |
| 5.98e-34 | FFCP PHASE2:Hg19::chr11:56859638..56859643,-#_1005718978f668bc236ef98d97bf066a | p@chr11:56859638..56859643, - |
| 5.98e-34 | FFCP PHASE2:Hg19::chr10:98014908..98014919,-#_1005718978f668bc236ef98d97bf066a | p@chr10:98014908..98014919, - |
| 5.98e-34 | FFCP PHASE1:Hg19::chr9:127260615..127260651,-#_1005718978f668bc236ef98d97bf066a | p@chr9:127260615..127260651, - |
| 5.98e-34 | FFCP PHASE2:Hg19::chr17:78171885..78171900,+#_1005718978f668bc236ef98d97bf066a | p@chr17:78171885..78171900, + |
| 5.98e-34 | FFCP PHASE2:Hg19::chr21:28820911..28820933,-#_1005718978f668bc236ef98d97bf066a | p1@ENST00000420186, p1@uc002ymh.2 |
| 5.98e-34 | FFCP PHASE2:Hg19::chr16:84218794..84218800,+#_1005718978f668bc236ef98d97bf066a | p@chr16:84218794..84218800, + |
| 5.98e-34 | FFCP PHASE2:Hg19::chrX:69645652..69645664,+#_1005718978f668bc236ef98d97bf066a | p7@GDPD2 |
| 5.98e-34 | FFCP PHASE2:Hg19::chr15:95561320..95561328,-#_1005718978f668bc236ef98d97bf066a | p@chr15:95561320..95561328, - |
| 5.98e-34 | FFCP PHASE1:Hg19::chr6:119812455..119812476,-#_1005718978f668bc236ef98d97bf066a | p1@uc003pyn.1 |
| 5.98e-34 | FFCP PHASE1:Hg19::chr10:98014908..98014919,-#_1005718978f668bc236ef98d97bf066a | p@chr10:98014908..98014919, - |
| 5.98e-34 | FFCP PHASE1:Hg19::chr1:157811772..157811796,-#_1005718978f668bc236ef98d97bf066a | p7@CD5L |
