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MCL coexpression mm9:3011

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Phase1 CAGE Peaks

 Short description
Mm9::chr15:81791248..81791276,-p2@Pmm1
Mm9::chr15:81791281..81791302,-p1@Pmm1
Mm9::chr7:35015332..35015343,-p3@Gpi1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004615phosphomannomutase activity0.00635494561255974
GO:0019307mannose biosynthetic process0.00635494561255974
GO:0017176phosphatidylinositol N-acetylglucosaminyltransferase activity0.00847279656663992
GO:0016868intramolecular transferase activity, phosphotransferases0.0118662327192853
GO:0006013mannose metabolic process0.0118662327192853
GO:0009059macromolecule biosynthetic process0.0118662327192853
GO:0046489phosphoinositide biosynthetic process0.0127001419728853
GO:0006506GPI anchor biosynthetic process0.0127001419728853
GO:0006505GPI anchor metabolic process0.0127001419728853
GO:0019319hexose biosynthetic process0.0127001419728853
GO:0046165alcohol biosynthetic process0.0127001419728853
GO:0046364monosaccharide biosynthetic process0.0127001419728853
GO:0016866intramolecular transferase activity0.0127001419728853
GO:0008375acetylglucosaminyltransferase activity0.0127001419728853
GO:0046474glycerophospholipid biosynthetic process0.0127001419728853
GO:0009058biosynthetic process0.0140788124567925
GO:0006497protein amino acid lipidation0.0155164378682723
GO:0030384phosphoinositide metabolic process0.0155164378682723
GO:0042158lipoprotein biosynthetic process0.0157007492328778
GO:0042157lipoprotein metabolic process0.0167282449499493
GO:0008654phospholipid biosynthetic process0.0167282449499493
GO:0006650glycerophospholipid metabolic process0.0167282449499493
GO:0046467membrane lipid biosynthetic process0.0198555935392707
GO:0016051carbohydrate biosynthetic process0.0208742371195118
GO:0008194UDP-glycosyltransferase activity0.0218107067656773
GO:0006644phospholipid metabolic process0.0282642874915134
GO:0019318hexose metabolic process0.0294755794378617
GO:0005996monosaccharide metabolic process0.0294755794378617
GO:0016758transferase activity, transferring hexosyl groups0.0294755794378617
GO:0006643membrane lipid metabolic process0.0310316901515955
GO:0016853isomerase activity0.0310316901515955
GO:0016757transferase activity, transferring glycosyl groups0.0451561517912396
GO:0008610lipid biosynthetic process0.0451561517912396
GO:0044262cellular carbohydrate metabolic process0.0458003654367581
GO:0006066alcohol metabolic process0.0458003654367581



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
nervous system8.35e-2975
central nervous system3.06e-2873
ectoderm-derived structure2.32e-2795
ectoderm2.32e-2795
presumptive ectoderm2.32e-2795
neurectoderm1.93e-2164
neural plate1.93e-2164
presumptive neural plate1.93e-2164
regional part of nervous system1.21e-2054
neural tube3.15e-1952
neural rod3.15e-1952
future spinal cord3.15e-1952
neural keel3.15e-1952
ecto-epithelium8.58e-1973
brain7.51e-1747
future brain7.51e-1747
gray matter7.99e-1734
structure with developmental contribution from neural crest2.16e-1692
regional part of brain2.42e-1646
brain grey matter1.45e-1429
regional part of telencephalon1.45e-1429
telencephalon1.45e-1429
pre-chordal neural plate2.00e-1449
anterior neural tube3.63e-1340
regional part of forebrain1.19e-1239
forebrain1.19e-1239
future forebrain1.19e-1239
cerebral cortex1.93e-1121
cerebral hemisphere1.93e-1121
pallium1.93e-1121
regional part of cerebral cortex3.31e-1017
occipital lobe1.28e-0710
visual cortex1.28e-0710
neocortex1.28e-0710
posterior neural tube5.15e-0712
chordal neural plate5.15e-0712


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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