MCL coexpression mm9:1939

Phase1 CAGE Peaks

	Short description
Mm9::chr11:102331048..102331066,-	p1@Itga2b
Mm9::chr16:30310859..30310875,-	p1@Gp5
Mm9::chr16:30310880..30310899,-	p2@Gp5
Mm9::chr4:43571033..43571054,-	p@chr4:43571033..43571054 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0050840	extracellular matrix binding	0.0179577864342013
GO:0022610	biological adhesion	0.0179577864342013
GO:0007155	cell adhesion	0.0179577864342013
GO:0005925	focal adhesion	0.0255897520182843
GO:0005924	cell-substrate adherens junction	0.0255897520182843
GO:0008305	integrin complex	0.0255897520182843
GO:0030055	cell-matrix junction	0.0255897520182843
GO:0007596	blood coagulation	0.0255897520182843
GO:0007599	hemostasis	0.0255897520182843
GO:0050817	coagulation	0.0255897520182843
GO:0005912	adherens junction	0.0255897520182843
GO:0007160	cell-matrix adhesion	0.0255897520182843
GO:0031589	cell-substrate adhesion	0.0255897520182843
GO:0050878	regulation of body fluid levels	0.0255897520182843
GO:0016323	basolateral plasma membrane	0.0255897520182843
GO:0043235	receptor complex	0.0255897520182843
GO:0042060	wound healing	0.0264209411005586
GO:0007229	integrin-mediated signaling pathway	0.0287339879187794
GO:0009897	external side of plasma membrane	0.0406326640110848

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
megakaryocyte-erythroid progenitor cell	3.24e-07	9

Uber Anatomy

Ontology term	p-value	n
subdivision of trunk	2.37e-08	66
lung	2.98e-07	14
respiratory tube	2.98e-07	14
respiration organ	2.98e-07	14
pair of lungs	2.98e-07	14
lung primordium	2.98e-07	14
lung bud	2.98e-07	14

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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