MCL coexpression mm9:1040

Phase1 CAGE Peaks

	Short description
Mm9::chr10:78054632..78054679,-	p1@Syde1
Mm9::chr11:100831178..100831208,+	p@chr11:100831178..100831208 +
Mm9::chr15:97661891..97661950,-	p1@Hdac7
Mm9::chr17:88997003..88997044,+	p1@Ston1
Mm9::chr18:60773155..60773181,-	p@chr18:60773155..60773181 -
Mm9::chr18:60773184..60773212,-	p@chr18:60773184..60773212 -
Mm9::chr1:191552143..191552205,+	p1@Ptpn14

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042134	rRNA primary transcript binding	0.023442419603706
GO:0003716	RNA polymerase I transcription termination factor activity	0.023442419603706
GO:0003715	transcription termination factor activity	0.023442419603706
GO:0006361	transcription initiation from RNA polymerase I promoter	0.023442419603706
GO:0006353	transcription termination	0.0252249413004837
GO:0065003	macromolecular complex assembly	0.0252249413004837
GO:0016599	caveolar membrane	0.0252249413004837
GO:0005901	caveola	0.0252249413004837
GO:0006360	transcription from RNA polymerase I promoter	0.0252249413004837
GO:0022607	cellular component assembly	0.0252249413004837
GO:0043624	cellular protein complex disassembly	0.0252249413004837
GO:0043241	protein complex disassembly	0.0252249413004837
GO:0032984	macromolecular complex disassembly	0.0252249413004837
GO:0022411	cellular component disassembly	0.0325027641996785
GO:0019843	rRNA binding	0.0325027641996785
GO:0030119	AP-type membrane coat adaptor complex	0.0325027641996785
GO:0030131	clathrin adaptor complex	0.0325027641996785
GO:0006352	transcription initiation	0.0325027641996785
GO:0030100	regulation of endocytosis	0.0397539599731975
GO:0030118	clathrin coat	0.0397539599731975

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
cardiovascular system	1.91e-08	23
circulatory system	1.91e-08	23
splanchnic layer of lateral plate mesoderm	6.65e-08	33
lung	1.34e-07	14
respiratory tube	1.34e-07	14
respiration organ	1.34e-07	14
pair of lungs	1.34e-07	14
lung primordium	1.34e-07	14
lung bud	1.34e-07	14
epithelial fold	2.81e-07	20

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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