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MCL coexpression mm9:805

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:17514007..17514018,-p@chr12:17514007..17514018
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Mm9::chr12:17514022..17514031,-p@chr12:17514022..17514031
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Mm9::chr13:38129788..38129801,-p@chr13:38129788..38129801
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Mm9::chr15:59430663..59430691,+p@chr15:59430663..59430691
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Mm9::chr16:20717297..20717309,-p9@Clcn2
Mm9::chr2:31326367..31326373,-p@chr2:31326367..31326373
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Mm9::chr3:52001982..52001995,-p@chr3:52001982..52001995
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Mm9::chr4:108520502..108520530,+p@chr4:108520502..108520530
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Mm9::chr6:113026311..113026321,-p@chr6:113026311..113026321
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005247voltage-gated chloride channel activity0.0320372344834076
GO:0022844voltage-gated anion channel activity0.0320372344834076
GO:0043168anion binding0.0365688293700127
GO:0031404chloride ion binding0.0365688293700127
GO:0005254chloride channel activity0.0365688293700127
GO:0006821chloride transport0.0365688293700127
GO:0005253anion channel activity0.0365688293700127



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
mature alpha-beta T cell1.51e-269
alpha-beta T cell1.51e-269
immature T cell1.51e-269
mature T cell1.51e-269
immature alpha-beta T cell1.51e-269
lymphoid lineage restricted progenitor cell4.89e-2412
CD4-positive, alpha-beta T cell1.19e-238
lymphocyte4.80e-2213
common lymphoid progenitor4.80e-2213
hematopoietic cell1.17e-2132
hematopoietic oligopotent progenitor cell1.17e-2132
hematopoietic stem cell1.17e-2132
angioblastic mesenchymal cell1.17e-2132
hematopoietic multipotent progenitor cell1.17e-2132
T cell1.94e-2111
pro-T cell1.94e-2111
thymocyte7.23e-186
double negative thymocyte7.23e-186
naive T cell7.23e-186
double-positive, alpha-beta thymocyte7.23e-186
CD4-positive, alpha-beta thymocyte7.23e-186
naive thymus-derived CD4-positive, alpha-beta T cell7.23e-186
DN4 thymocyte7.23e-186
DN1 thymic pro-T cell7.23e-186
DN2 thymocyte7.23e-186
DN3 thymocyte7.23e-186
immature single positive thymocyte7.23e-186
early T lineage precursor7.23e-186
mature CD4 single-positive thymocyte7.23e-186
resting double-positive thymocyte7.23e-186
double-positive blast7.23e-186
CD69-positive double-positive thymocyte7.23e-186
CD69-positive, CD4-positive single-positive thymocyte7.23e-186
CD4-positive, CD8-intermediate double-positive thymocyte7.23e-186
CD24-positive, CD4 single-positive thymocyte7.23e-186
nucleate cell1.45e-1716
leukocyte2.02e-1617
nongranular leukocyte2.02e-1617
connective tissue cell3.49e-1646
mesenchymal cell3.49e-1646
motile cell6.04e-1554
stem cell2.99e-1197
hematopoietic lineage restricted progenitor cell1.43e-1025
somatic stem cell2.19e-0891
multi fate stem cell2.19e-0891

Uber Anatomy
Ontology termp-valuen
connective tissue3.49e-1646


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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