MCL coexpression mm9:1978

Phase1 CAGE Peaks

	Short description
Mm9::chr11:61191808..61191849,-	p2@Slc47a1
Mm9::chr13:93616609..93616624,+	p@chr13:93616609..93616624 +
Mm9::chr9:46048823..46048828,+	p4@Apoa4
Mm9::chr9:46048865..46048876,+	p3@Apoa4

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0006855	multidrug transport	0.00588879748364596
GO:0030300	regulation of cholesterol absorption	0.00588879748364596
GO:0030299	cholesterol absorption	0.00588879748364596
GO:0044241	lipid digestion	0.00588879748364596
GO:0042627	chylomicron	0.00659509178698858
GO:0050892	intestinal absorption	0.00706578256317182
GO:0015893	drug transport	0.00732647433950719
GO:0022600	digestive system process	0.00732647433950719
GO:0015238	drug transporter activity	0.00732647433950719
GO:0042493	response to drug	0.0141234337457087
GO:0015297	antiporter activity	0.0156884018441022
GO:0007586	digestion	0.0156884018441022
GO:0005319	lipid transporter activity	0.0166511017120968
GO:0042157	lipoprotein metabolic process	0.0191533287968437
GO:0006869	lipid transport	0.0231971854661205
GO:0006810	transport	0.0408473186988738
GO:0051234	establishment of localization	0.0408473186988738
GO:0015291	secondary active transmembrane transporter activity	0.0458476782780808
GO:0051179	localization	0.04657740421181

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}