MCL coexpression mm9:1553

Phase1 CAGE Peaks

	Short description
Mm9::chr11:116704833..116704883,+	p1@1110005A03Rik
Mm9::chr14:21208135..21208149,-	p2@Dnajc9
Mm9::chr9:79641328..79641348,-	p2@Tmem30a
Mm9::chr9:79641352..79641378,-	p4@Tmem30a
Mm9::chrX:45866695..45866742,-	p2@Aifm1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004174	electron-transferring-flavoprotein dehydrogenase activity	0.0203785365697633
GO:0016649	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	0.0203785365697633
GO:0006309	DNA fragmentation during apoptosis	0.0344301086670188
GO:0006921	cell structure disassembly during apoptosis	0.0344301086670188
GO:0030262	apoptotic nuclear changes	0.0344301086670188
GO:0005758	mitochondrial intermembrane space	0.0344301086670188
GO:0006308	DNA catabolic process	0.0344301086670188
GO:0005741	mitochondrial outer membrane	0.0344301086670188
GO:0008637	apoptotic mitochondrial changes	0.0344301086670188
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	0.0344301086670188
GO:0031970	organelle envelope lumen	0.0344301086670188
GO:0031968	organelle outer membrane	0.0344301086670188
GO:0022411	cellular component disassembly	0.0344301086670188
GO:0006997	nuclear organization and biogenesis	0.037771268991134

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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