MCL coexpression mm9:684

Phase1 CAGE Peaks

	Short description
Mm9::chr10:116500820..116500858,-	p1@Cct2
Mm9::chr11:22890617..22890654,+	p1@Cct4
Mm9::chr11:3863990..3864024,+	p1@Pes1
Mm9::chr15:31531471..31531538,-	p1@Cct5
Mm9::chr15:77801160..77801173,-	p2@Eif3d
Mm9::chr15:77801180..77801254,-	p1@Eif3d
Mm9::chr15:78905639..78905675,+	p1@Eif3l
Mm9::chr3:88101037..88101066,+	p2@Cct3
Mm9::chr3:88101069..88101115,+	p1@Cct3
Mm9::chr4:138908232..138908261,-	p2@Gm5633 p2@Gm9178 p2@Mrto4

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005832	chaperonin-containing T-complex	8.05972835473819e-12
GO:0051082	unfolded protein binding	4.86318037139402e-08
GO:0044445	cytosolic part	2.32295397199559e-07
GO:0006457	protein folding	6.46891643753644e-07
GO:0005829	cytosol	2.36143671966275e-05
GO:0005524	ATP binding	0.00245854689842092
GO:0032559	adenyl ribonucleotide binding	0.00245854689842092
GO:0044267	cellular protein metabolic process	0.00245854689842092
GO:0044260	cellular macromolecule metabolic process	0.00245854689842092
GO:0030554	adenyl nucleotide binding	0.00245854689842092
GO:0019538	protein metabolic process	0.00245854689842092
GO:0032553	ribonucleotide binding	0.00349489910110125
GO:0032555	purine ribonucleotide binding	0.00349489910110125
GO:0043234	protein complex	0.00349489910110125
GO:0017076	purine nucleotide binding	0.0037554488061163
GO:0007000	nucleolus organization and biogenesis	0.00437479430421456
GO:0000166	nucleotide binding	0.00518423122245799
GO:0000089	mitotic metaphase	0.00518423122245799
GO:0022613	ribonucleoprotein complex biogenesis and assembly	0.00581672890966684
GO:0032991	macromolecular complex	0.0059380503134956
GO:0051323	metaphase	0.00666361437877628
GO:0006997	nuclear organization and biogenesis	0.0273469592557103
GO:0044444	cytoplasmic part	0.0273469592557103
GO:0043170	macromolecule metabolic process	0.028407679656586
GO:0006413	translational initiation	0.0392642313831404
GO:0000793	condensed chromosome	0.0392642313831404
GO:0044238	primary metabolic process	0.0481885656443548
GO:0044237	cellular metabolic process	0.0481885656443548

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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