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MCL coexpression mm9:114

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:31329624..31329676,-p3@Rnf217
Mm9::chr11:35358024..35358067,+p4@Slit3
Mm9::chr11:43342261..43342298,+p1@Ccnjl
Mm9::chr11:43342307..43342322,+p2@Ccnjl
Mm9::chr11:43400570..43400574,+p1@4933415A04Rik
Mm9::chr11:66725485..66725505,+p1@Pirt
Mm9::chr11:66725506..66725546,+p2@Pirt
Mm9::chr11:66725554..66725573,+p3@Pirt
Mm9::chr11:94816723..94816733,+p@chr11:94816723..94816733
+
Mm9::chr11:96164821..96164865,+p1@Hoxb5
Mm9::chr11:96164868..96164875,+p5@Hoxb5
Mm9::chr11:96175972..96175978,+p@chr11:96175972..96175978
+
Mm9::chr11:96176093..96176104,+p@chr11:96176093..96176104
+
Mm9::chr11:96176110..96176149,+p@chr11:96176110..96176149
+
Mm9::chr14:104214967..104214980,-p@chr14:104214967..104214980
-
Mm9::chr14:104242355..104242372,-p@chr14:104242355..104242372
-
Mm9::chr14:104243404..104243415,-p12@Ednrb
Mm9::chr14:104243425..104243438,-p6@Ednrb
Mm9::chr14:104243463..104243484,-p4@Ednrb
Mm9::chr14:104243485..104243515,-p3@Ednrb
Mm9::chr14:104243517..104243522,-p14@Ednrb
Mm9::chr14:104243531..104243557,-p2@Ednrb
Mm9::chr14:17407549..17407575,-p3@Rarb
Mm9::chr15:102928215..102928218,-p@chr15:102928215..102928218
-
Mm9::chr15:102932532..102932548,-p@chr15:102932532..102932548
-
Mm9::chr15:102998460..102998477,-p2@Smug1
Mm9::chr16:38910223..38910228,+p@chr16:38910223..38910228
+
Mm9::chr17:15966789..15966803,-p@chr17:15966789..15966803
-
Mm9::chr17:15966846..15966866,-p@chr17:15966846..15966866
-
Mm9::chr17:68273854..68273859,-p@chr17:68273854..68273859
-
Mm9::chr17:75404863..75404905,+p1@Ltbp1
Mm9::chr18:25224581..25224593,+p7@Fhod3
Mm9::chr18:25224624..25224637,+p8@Fhod3
Mm9::chr18:43367378..43367391,+p4@LOC100047004
p4@Stk32a
Mm9::chr18:43425442..43425450,+p@chr18:43425442..43425450
+
Mm9::chr18:43488317..43488321,-p@chr18:43488317..43488321
-
Mm9::chr18:43598025..43598036,-p9@Dpysl3
Mm9::chr18:4980585..4980596,+p@chr18:4980585..4980596
+
Mm9::chr18:4980598..4980625,+p@chr18:4980598..4980625
+
Mm9::chr18:84257094..84257108,-p@chr18:84257094..84257108
-
Mm9::chr18:89035657..89035660,-p@chr18:89035657..89035660
-
Mm9::chr19:3414464..3414481,-p1@Gal
Mm9::chr1:92965124..92965151,+p@chr1:92965124..92965151
+
Mm9::chr2:119586145..119586157,-p2@Ltk
Mm9::chr2:119624214..119624225,+p7@Tyro3
Mm9::chr2:31305411..31305419,+p@chr2:31305411..31305419
+
Mm9::chr2:4480691..4480702,+p17@Frmd4a
Mm9::chr2:4480747..4480752,+p41@Frmd4a
Mm9::chr2:44946359..44946364,-p@chr2:44946359..44946364
-
Mm9::chr2:67492047..67492052,+p@chr2:67492047..67492052
+
Mm9::chr2:74565247..74565258,+p3@Hoxd4
Mm9::chr2:74565306..74565327,+p2@Hoxd4
Mm9::chr2:74583733..74583738,+p13@Hoxd3
Mm9::chr2:74583741..74583750,+p10@Hoxd3
Mm9::chr2:74583776..74583815,+p3@Hoxd3
Mm9::chr4:109965106..109965109,-p@chr4:109965106..109965109
-
Mm9::chr4:109965324..109965337,-p13@Elavl4
Mm9::chr4:149668115..149668119,+p@chr4:149668115..149668119
+
Mm9::chr4:98484378..98484397,-p1@Kank4
Mm9::chr5:118291893..118291934,+p1@Nos1
Mm9::chr5:118291939..118291948,+p5@Nos1
Mm9::chr5:135965066..135965107,-p@chr5:135965066..135965107
-
Mm9::chr5:45167917..45167920,-p@chr5:45167917..45167920
-
Mm9::chr5:46030607..46030647,-p1@Fam184b
Mm9::chr5:46030683..46030696,-p6@Fam184b
Mm9::chr5:67359798..67359814,+p3@Limch1
Mm9::chr5:67486110..67486118,-p@chr5:67486110..67486118
-
Mm9::chr5:67487233..67487235,-p@chr5:67487233..67487235
-
Mm9::chr5:67489910..67489925,+p@chr5:67489910..67489925
+
Mm9::chr5:67490284..67490302,-p1@Phox2b
Mm9::chr5:67490333..67490342,-p5@Phox2b
Mm9::chr5:67490346..67490357,-p4@Phox2b
Mm9::chr5:67490391..67490404,-p3@Phox2b
Mm9::chr5:67490412..67490421,-p6@Phox2b
Mm9::chr5:67597048..67597059,+p@chr5:67597048..67597059
+
Mm9::chr6:118105351..118105370,-p@chr6:118105351..118105370
-
Mm9::chr6:118116455..118116458,-p@chr6:118116455..118116458
-
Mm9::chr6:118147336..118147353,-p1@Ret
Mm9::chr6:118147365..118147366,-p5@Ret
Mm9::chr6:118147374..118147392,-p2@Ret
Mm9::chr6:118147404..118147415,-p3@Ret
Mm9::chr6:118147750..118147761,-p7@Ret
Mm9::chr6:118147768..118147779,-p6@Ret
Mm9::chr6:118147812..118147826,-p4@Ret
Mm9::chr7:138703922..138703933,+p2@Bub3
Mm9::chr7:138703939..138703942,+p3@Bub3
Mm9::chr7:38376166..38376169,-p@chr7:38376166..38376169
-
Mm9::chr7:54051521..54051526,+p4@Gtf2h1
Mm9::chr7:94427398..94427402,+p@chr7:94427398..94427402
+
Mm9::chr7:98820891..98820900,+p34@Dlg2
Mm9::chr7:98821147..98821167,+p26@Dlg2
Mm9::chr8:11912972..11913001,+p@chr8:11912972..11913001
+
Mm9::chr8:59799533..59799566,-p@chr8:59799533..59799566
-
Mm9::chr9:109735573..109735587,+p5@Nme6
Mm9::chr9:48719025..48719051,-p@chr9:48719025..48719051
-
Mm9::chr9:48719172..48719183,-p1@Htr3a
Mm9::chr9:48719225..48719245,-p3@Htr3a
Mm9::chr9:54829289..54829303,+p2@Chrna5
Mm9::chr9:54874331..54874346,-p2@Chrna3
Mm9::chr9:54874348..54874406,-p1@Chrna3
Mm9::chr9:54891807..54891824,-p@chr9:54891807..54891824
-
Mm9::chr9:54896368..54896400,-p2@Chrnb4
Mm9::chr9:54896555..54896599,-p1@Chrnb4
Mm9::chr9:65619254..65619257,-p@chr9:65619254..65619257
-
Mm9::chrX:56821245..56821271,-p2@Fgf13


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0035094response to nicotine5.90605161753699e-05
GO:0007271synaptic transmission, cholinergic0.000203216950164617
GO:0004889nicotinic acetylcholine-activated cation-selective channel activity0.000203216950164617
GO:0014070response to organic cyclic substance0.000227052508675745
GO:0043279response to alkaloid0.000227052508675745
GO:0005230extracellular ligand-gated ion channel activity0.000254806426551577
GO:0060084synaptic transmission involved in micturition0.000452052441777918
GO:0015276ligand-gated ion channel activity0.000452052441777918
GO:0022834ligand-gated channel activity0.000452052441777918
GO:0030594neurotransmitter receptor activity0.000466777603105592
GO:0042165neurotransmitter binding0.000466777603105592
GO:0010033response to organic substance0.000501887345624438
GO:0035095behavioral response to nicotine0.000798053674773339
GO:0060073micturition0.000798053674773339
GO:0045211postsynaptic membrane0.000798053674773339
GO:0044456synapse part0.0010976946821783
GO:0005231excitatory extracellular ligand-gated ion channel activity0.0010976946821783
GO:0005892nicotinic acetylcholine-gated receptor-channel complex0.00284133150154998
GO:0004714transmembrane receptor protein tyrosine kinase activity0.00316725798069038
GO:0007274neuromuscular synaptic transmission0.00441938523556918
GO:0019199transmembrane receptor protein kinase activity0.00465758495744733
GO:0003014renal system process0.00468260819794851
GO:0003012muscle system process0.00595660893513175
GO:0006936muscle contraction0.00595660893513175
GO:0006940regulation of smooth muscle contraction0.006140218008909
GO:0043565sequence-specific DNA binding0.00933951148039214
GO:0001755neural crest cell migration0.0105141501010203
GO:0022836gated channel activity0.0119428038023244
GO:0006939smooth muscle contraction0.0125377475929431
GO:0001657ureteric bud development0.0172385332321902
GO:0014032neural crest cell development0.0172385332321902
GO:0014033neural crest cell differentiation0.0172385332321902
GO:0006937regulation of muscle contraction0.0177771087471225
GO:0003700transcription factor activity0.0182128430608801
GO:0009653anatomical structure morphogenesis0.0182128430608801
GO:0017065single-strand selective uracil DNA N-glycosylase activity0.0182128430608801
GO:0001600endothelin-B receptor activity0.0182128430608801
GO:0042737drug catabolic process0.0182128430608801
GO:0007497posterior midgut development0.0182128430608801
GO:0047276N-acetyllactosaminide 3-alpha-galactosyltransferase activity0.0182128430608801
GO:0042738exogenous drug catabolic process0.0182128430608801
GO:0014031mesenchymal cell development0.0190338594545024
GO:0048762mesenchymal cell differentiation0.0190338594545024
GO:0004713protein-tyrosine kinase activity0.0206593250905961
GO:0042391regulation of membrane potential0.0206593250905961
GO:0005216ion channel activity0.0206593250905961
GO:0048856anatomical structure development0.0206593250905961
GO:0050801ion homeostasis0.021741001755456
GO:0022838substrate specific channel activity0.021741001755456
GO:0001656metanephros development0.021741001755456
GO:0022803passive transmembrane transporter activity0.0240694773202363
GO:0015267channel activity0.0240694773202363
GO:0030054cell junction0.0240694773202363
GO:0048731system development0.0240694773202363
GO:0004844uracil DNA N-glycosylase activity0.0240694773202363
GO:0007171transmembrane receptor protein tyrosine kinase activation (dimerization)0.0240694773202363
GO:0051926negative regulation of calcium ion transport0.0240694773202363
GO:0004962endothelin receptor activity0.0240694773202363
GO:0003708retinoic acid receptor activity0.0240694773202363
GO:0014056regulation of acetylcholine secretion0.0240694773202363
GO:0007494midgut development0.0240694773202363
GO:0014055acetylcholine secretion0.0240694773202363
GO:0031981nuclear lumen0.0244049524193499
GO:0007268synaptic transmission0.0244085965294841
GO:0065007biological regulation0.0265736740763895
GO:0005667transcription factor complex0.0288895254695332
GO:0030534adult behavior0.0288938309675815
GO:0042221response to chemical stimulus0.0288938309675815
GO:0048878chemical homeostasis0.0288938309675815
GO:0006811ion transport0.0288938309675815
GO:0007275multicellular organismal development0.0296480129899384
GO:0004517nitric-oxide synthase activity0.0302262808074342
GO:0043267negative regulation of potassium ion transport0.0302262808074342
GO:0048484enteric nervous system development0.0302262808074342
GO:0050789regulation of biological process0.0313445092488392
GO:0019226transmission of nerve impulse0.0328830511673025
GO:0043233organelle lumen0.0328830511673025
GO:0031974membrane-enclosed lumen0.0328830511673025
GO:0043235receptor complex0.0345964800045106
GO:0007389pattern specification process0.0346587170262196
GO:0001822kidney development0.0346587170262196
GO:0002028regulation of sodium ion transport0.0359040941619587
GO:0043271negative regulation of ion transport0.0359040941619587
GO:0005261cation channel activity0.0364861394112969
GO:0001655urogenital system development0.0384936939922191
GO:0009887organ morphogenesis0.0404586346824031
GO:0043266regulation of potassium ion transport0.0404586346824031
GO:0051346negative regulation of hydrolase activity0.0404586346824031
GO:0000702oxidized base lesion DNA N-glycosylase activity0.0404586346824031
GO:0050773regulation of dendrite development0.0404586346824031
GO:0048814regulation of dendrite morphogenesis0.0404586346824031
GO:0017144drug metabolic process0.0404586346824031
GO:0007167enzyme linked receptor protein signaling pathway0.0427126089843394
GO:0032502developmental process0.0436375440710394
GO:0044451nucleoplasm part0.0437717283163608
GO:0048048embryonic eye morphogenesis0.0455429611551728
GO:0055012ventricular cardiac muscle cell differentiation0.0455429611551728
GO:0004396hexokinase activity0.0455429611551728
GO:0005615extracellular space0.0463548692610854
GO:0046873metal ion transmembrane transporter activity0.0470136409072034
GO:0005654nucleoplasm0.0483471950138859



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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