MCL coexpression mm9:1075

Phase1 CAGE Peaks

	Short description
Mm9::chr11:50767247..50767270,-	p1@Prop1
Mm9::chr12:110691043..110691059,+	p13@Dlk1
Mm9::chr12:110853772..110853783,-	p@chr12:110853772..110853783 -
Mm9::chr14:66024023..66024029,-	p@chr14:66024023..66024029 -
Mm9::chr1:157598849..157598868,-	p@chr1:157598849..157598868 -
Mm9::chr2:157340090..157340102,-	p@chr2:157340090..157340102 -
Mm9::chr6:30530875..30530886,+	p@chr6:30530875..30530886 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0048852	diencephalon morphogenesis	0.00915600407927713
GO:0048850	hypophysis morphogenesis	0.00915600407927713
GO:0060126	somatotropin secreting cell differentiation	0.00915600407927713
GO:0048853	forebrain morphogenesis	0.00915600407927713
GO:0060070	Wnt receptor signaling pathway through beta-catenin	0.00915600407927713
GO:0021979	hypothalamus cell differentiation	0.00915600407927713
GO:0021854	hypothalamus development	0.00915600407927713
GO:0048854	brain morphogenesis	0.010681419486589
GO:0001515	opioid peptide activity	0.0118675935948906
GO:0021984	adenohypophysis development	0.0128162988067131
GO:0021761	limbic system development	0.019414378727577
GO:0008022	protein C-terminus binding	0.0213523059911787
GO:0008013	beta-catenin binding	0.0213523059911787
GO:0021983	pituitary gland development	0.0274454432114493
GO:0021536	diencephalon development	0.028458821421906

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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