MCL coexpression mm9:493

Phase1 CAGE Peaks

	Short description
Mm9::chr12:80081660..80081667,-	p@chr12:80081660..80081667 -
Mm9::chr13:41942916..41942930,-	p7@9530008L14Rik
Mm9::chr14:59819868..59819890,+	p5@Rcbtb1
Mm9::chr17:34741829..34741866,+	p6@Agpat1
Mm9::chr17:34741874..34741896,+	p8@Agpat1
Mm9::chr17:34742434..34742443,+	p16@Agpat1
Mm9::chr19:32135843..32135852,-	p8@Asah2
Mm9::chr19:32135856..32135871,-	p5@Asah2
Mm9::chr2:29659138..29659154,+	p@chr2:29659138..29659154 +
Mm9::chr2:29659170..29659180,+	p@chr2:29659170..29659180 +
Mm9::chr7:52970037..52970048,-	p@chr7:52970037..52970048 -
Mm9::chr7:52970050..52970066,-	p@chr7:52970050..52970066 -
Mm9::chr7:52970068..52970099,-	p4@Sphk2
Mm9::chr8:26864686..26864722,-	p2@Ddhd2
Mm9::chr8:26864824..26864896,-	p1@Ddhd2

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006629	lipid metabolic process	0.000103886642702824
GO:0006643	membrane lipid metabolic process	0.00102577637870691
GO:0044255	cellular lipid metabolic process	0.00102577637870691
GO:0006665	sphingolipid metabolic process	0.00433710004817991
GO:0046467	membrane lipid biosynthetic process	0.00771790938475867
GO:0017050	D-erythro-sphingosine kinase activity	0.00771790938475867
GO:0046511	sphinganine biosynthetic process	0.00771790938475867
GO:0006669	sphinganine-1-phosphate biosynthetic process	0.00771790938475867
GO:0006667	sphinganine metabolic process	0.0112242048383209
GO:0008481	sphinganine kinase activity	0.0112242048383209
GO:0006668	sphinganine-1-phosphate metabolic process	0.0112242048383209
GO:0006670	sphingosine metabolic process	0.0154307449992403
GO:0017040	ceramidase activity	0.0264396648314999
GO:0046520	sphingoid biosynthetic process	0.0264396648314999
GO:0008610	lipid biosynthetic process	0.0346849533115712
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	0.0346849533115712
GO:0004467	long-chain-fatty-acid-CoA ligase activity	0.0381467145022446
GO:0007205	protein kinase C activation	0.0381467145022446
GO:0004143	diacylglycerol kinase activity	0.0381467145022446
GO:0015645	fatty-acid ligase activity	0.0381467145022446
GO:0016411	acylglycerol O-acyltransferase activity	0.0381467145022446
GO:0001676	long-chain fatty acid metabolic process	0.0392073114929924
GO:0030148	sphingolipid biosynthetic process	0.0401748033217997
GO:0044238	primary metabolic process	0.048660483088478

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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