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DOID:2531

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Name:hematologic cancer
Namespace:disease_ontology
Definition:"An immune system cancer located_in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes." [url:http://en.wikipedia.org/wiki/Blood_cancer, url:http://www.cancer.gov/dictionary/?CdrID=45708]
Xrefs:
links:

MSH:D019337
NCI:C27134
SNOMEDCT_2010_1_31:414388001
SNOMEDCT_2010_1_31:414644002

UMLS_CUI:C0376544
Synonyms: "blood cancer" EXACT [CSP2005:2004-0139]
"Hematologic malignancy" EXACT [SNOMEDCT_2005_07_31:269475001]
"Hematologic malignancy (disorder)" EXACT [SNOMEDCT_2005_07_31:127221002]
"Hematologic neoplasm (disorder)" EXACT [SNOMEDCT_2005_07_31:129154003]
"Hematological tumors" EXACT [NCI2004_11_17:C27134]
"hematopoietic and lymphoid system tumor" EXACT []
"hematopoietic cancer" EXACT []
"hematopoietic neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414388001]
"hematopoietic tumors" EXACT [NCI2004_11_17:C27134]
"malignant hematopoietic neoplasm (morphologic abnormality)" EXACT [SNOMEDCT_2005_07_31:414644002]
Alt_id: DOID:1034
DOID:2532

Ontology association<br>Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:DOID:0060083(immune system cancer)



Children


is a:DOID:0060058 (lymphoma),DOID:1240 (leukemia),DOID:4960 (bone marrow cancer)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples

Human (Homo sapiens)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10422-106C8 (Burkitt's lymphoma cell line:DAUDI)
  • 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10435-106E3 (Hodgkin's lymphoma cell line:HD-Mar2)

... further results Mouse (Mus musculus)

  • 10399-106A3 (acute myeloid leukemia (FAB M5) cell line:THP-1 (fresh))
  • 10400-106A4 (acute myeloid leukemia (FAB M5) cell line:THP-1 (revived))
  • 10405-106A9 (acute myeloid leukemia (FAB M5) cell line:THP-1 (thawed))
  • 10409-106B4 (chronic myelogenous leukemia cell line:KU812)
  • 10416-106C2 (chronic lymphocytic leukemia (T-CLL) cell line:SKW-3)
  • 10421-106C7 (adult T-cell leukemia cell line:ATN-1)
  • 10422-106C8 (Burkitt's lymphoma cell line:DAUDI)
  • 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
  • 10429-106D6 (acute lymphoblastic leukemia (T-ALL) cell line:HPB-ALL)
  • 10435-106E3 (Hodgkin's lymphoma cell line:HD-Mar2)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:2531 (hematologic cancer), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
7.91e-91FFCP PHASE2:Hg19::chr6:135513595..135513617,+#_a20eb265833d1e6cc9022a91dc375fc6p4@MYB
7.91e-91FFCP PHASE1:Hg19::chr6:135513595..135513617,+#_a20eb265833d1e6cc9022a91dc375fc6p4@MYB
1.58e-86FFCP PHASE2:Mm9::chr10:76688464..76688474,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688464..76688474, +
1.58e-86FFCP PHASE1:Mm9::chr11:102331415..102331424,-#_32c0398a2d5eea688b99633ad877d6fap9@Itga2b
1.58e-86FFCP PHASE1:Mm9::chr10:76688454..76688462,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688454..76688462, +
1.58e-86FFCP PHASE1:Mm9::chr10:76688464..76688474,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688464..76688474, +
1.58e-86FFCP PHASE2:Mm9::chr10:76688454..76688462,+#_32c0398a2d5eea688b99633ad877d6fap@chr10:76688454..76688462, +
1.58e-86FFCP PHASE2:Mm9::chr11:102331415..102331424,-#_32c0398a2d5eea688b99633ad877d6fap9@Itga2b
3.61e-86FFCP PHASE1:Hg19::chr12:58329793..58329806,-#_38b14e5ff00ce6017583d44d6a49e81ep2@ENST00000547492
3.61e-86FFCP PHASE2:Hg19::chr12:58329793..58329806,-#_38b14e5ff00ce6017583d44d6a49e81ep2@ENST00000547492
1.2e-85FFCP PHASE1:Hg19::chr12:58329776..58329791,-#_f218044066aa1b4044348e9e878e50d3p3@ENST00000547492
1.2e-85FFCP PHASE2:Hg19::chr12:58329776..58329791,-#_f218044066aa1b4044348e9e878e50d3p3@ENST00000547492
4.4e-85FFCP PHASE2:Hg19::chr6:135533394..135533403,+#_56353b6a30b232628212414a487bca05p@chr6:135533394..135533403, +
4.4e-85FFCP PHASE1:Hg19::chr6:135533394..135533403,+#_56353b6a30b232628212414a487bca05p@chr6:135533394..135533403, +
2.22e-77FFCP PHASE2:Hg19::chr6:135502472..135502489,+#_571b16c6de62d105bc30cfd931653e94p3@MYB
2.22e-77FFCP PHASE1:Hg19::chr6:135502472..135502489,+#_571b16c6de62d105bc30cfd931653e94p3@MYB
9.4e-76FFCP PHASE2:Hg19::chr6:68598272..68598298,-#_1c20b7e1e044bf18182d7d7cbe5b1b69p@chr6:68598272..68598298, -
9.4e-76FFCP PHASE1:Hg19::chr6:68598272..68598298,-#_1c20b7e1e044bf18182d7d7cbe5b1b69p@chr6:68598272..68598298, -
2.03e-75FFCP PHASE1:Hg19::chr16:29674970..29675007,+#_071eab6eb6b5b23c25ed8cdd46c1f0d2p4@SPN
2.03e-75FFCP PHASE2:Hg19::chr16:29674970..29675007,+#_071eab6eb6b5b23c25ed8cdd46c1f0d2p4@SPN
7.69e-75FFCP PHASE1:Hg19::chr12:58329762..58329773,-#_db0c148d1c4b9f19a85e60f2021a87adp5@ENST00000547492
7.69e-75FFCP PHASE2:Hg19::chr12:58329762..58329773,-#_db0c148d1c4b9f19a85e60f2021a87adp5@ENST00000547492
1.51e-73FFCP PHASE2:Hg19::chr1:202129105..202129140,-#_cc3d9a859d7f5c9041f4240c599a1dd8p2@PTPN7
1.51e-73FFCP PHASE1:Hg19::chr1:202129105..202129140,-#_cc3d9a859d7f5c9041f4240c599a1dd8p2@PTPN7
1.25e-71FFCP PHASE2:Hg19::chr6:68592986..68593000,-#_a282651b8f9239b01fffc30b8adc6674p@chr6:68592986..68593000, -
1.25e-71FFCP PHASE1:Hg19::chr6:68592986..68593000,-#_a282651b8f9239b01fffc30b8adc6674p@chr6:68592986..68593000, -
1.49e-71FFCP PHASE2:Hg19::chr6:68598314..68598325,-#_23d335eb9923a0dec315c31d67aaa239p@chr6:68598314..68598325, -
1.49e-71FFCP PHASE1:Hg19::chr6:68598314..68598325,-#_23d335eb9923a0dec315c31d67aaa239p@chr6:68598314..68598325, -
7.94e-68FFCP PHASE2:Hg19::chr6:68593536..68593560,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68593536..68593560, -
7.94e-68FFCP PHASE2:Hg19::chr6:68596384..68596400,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68596384..68596400, -
7.94e-68FFCP PHASE1:Hg19::chr6:68593536..68593560,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68593536..68593560, -
7.94e-68FFCP PHASE1:Hg19::chr6:68596384..68596400,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68596384..68596400, -
7.94e-68FFCP PHASE2:Hg19::chr6:68591611..68591627,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68591611..68591627, -
7.94e-68FFCP PHASE1:Hg19::chr6:68591611..68591627,-#_56d155c7f85e0ef73d39dec803e7e845p@chr6:68591611..68591627, -
3.59e-67FFCP PHASE1:Hg19::chr16:29675010..29675041,+#_153785aaa3545f8fa39fe9637628409ep5@SPN
3.59e-67FFCP PHASE2:Hg19::chr16:29675010..29675041,+#_153785aaa3545f8fa39fe9637628409ep5@SPN
1.24e-65FFCP PHASE2:Hg19::chr6:135516978..135516993,+#_de3cbb14e2bb319f3dac3ed3556a7862p7@MYB
1.24e-65FFCP PHASE1:Hg19::chr6:135516978..135516993,+#_de3cbb14e2bb319f3dac3ed3556a7862p7@MYB
1.33e-65FFCP PHASE2:Mm9::chr2:156853485..156853494,-#_fee63bdc12ab2100f254cee5375e40cdp13@9830001H06Rik
1.33e-65FFCP PHASE1:Mm9::chr19:8798483..8798487,+#_fee63bdc12ab2100f254cee5375e40cdp1@ENSMUST00000082787
1.33e-65FFCP PHASE2:Mm9::chrX:160480258..160480272,-#_fee63bdc12ab2100f254cee5375e40cdp@chrX:160480258..160480272, -
1.33e-65FFCP PHASE1:Mm9::chr2:156853485..156853494,-#_fee63bdc12ab2100f254cee5375e40cdp13@9830001H06Rik
1.33e-65FFCP PHASE2:Mm9::chr19:8798483..8798487,+#_fee63bdc12ab2100f254cee5375e40cdp1@ENSMUST00000082787
1.33e-65FFCP PHASE1:Mm9::chrX:160480258..160480272,-#_fee63bdc12ab2100f254cee5375e40cdp@chrX:160480258..160480272, -
1.56e-64FFCP PHASE2:Hg19::chr6:68598245..68598268,-#_c24d5dc18edd1a1582d07cad66ffc958p@chr6:68598245..68598268, -
1.56e-64FFCP PHASE1:Hg19::chr6:68598245..68598268,-#_c24d5dc18edd1a1582d07cad66ffc958p@chr6:68598245..68598268, -
3.76e-64FFCP PHASE2:Hg19::chr6:68598507..68598519,-#_bb905090403d5bf872bb0fb28ea3eecep@chr6:68598507..68598519, -
3.76e-64FFCP PHASE1:Hg19::chr6:68598507..68598519,-#_bb905090403d5bf872bb0fb28ea3eecep@chr6:68598507..68598519, -
4.16e-64FFCP PHASE2:Hg19::chr6:68598587..68598598,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68598587..68598598, -
4.16e-64FFCP PHASE2:Hg19::chr6:68595369..68595417,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68595369..68595417, -
4.16e-64FFCP PHASE1:Hg19::chr6:68598587..68598598,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68598587..68598598, -
4.16e-64FFCP PHASE1:Hg19::chr6:68595369..68595417,-#_fb2ad0a96ba2594fe0e224b9197e9d11p@chr6:68595369..68595417, -
2.54e-62FFCP PHASE2:Hg19::chr11:17297848..17297868,+#_203606c2f0ddd23c1582a1762009e2f5p9@NUCB2
2.54e-62FFCP PHASE1:Hg19::chr11:17297848..17297868,+#_203606c2f0ddd23c1582a1762009e2f5p9@NUCB2
1.55e-60FFCP PHASE2:Hg19::chr6:135526382..135526388,+#_036d20cc396ac332cc7bb1d0c6c6a4b6p@chr6:135526382..135526388, +
1.55e-60FFCP PHASE1:Hg19::chr6:135526382..135526388,+#_036d20cc396ac332cc7bb1d0c6c6a4b6p@chr6:135526382..135526388, +
2.15e-60FFCP PHASE1:Hg19::chr6:68598534..68598555,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68598534..68598555, -
2.15e-60FFCP PHASE2:Hg19::chr6:68596826..68596859,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596826..68596859, -
2.15e-60FFCP PHASE2:Hg19::chr6:68592948..68592958,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68592948..68592958, -
2.15e-60FFCP PHASE1:Hg19::chr6:68596826..68596859,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596826..68596859, -
2.15e-60FFCP PHASE1:Hg19::chr6:68592948..68592958,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68592948..68592958, -
2.15e-60FFCP PHASE2:Hg19::chr6:68597599..68597612,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68597599..68597612, -
2.15e-60FFCP PHASE2:Hg19::chr6:68596698..68596715,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596698..68596715, -
2.15e-60FFCP PHASE1:Hg19::chr6:68597599..68597612,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68597599..68597612, -
2.15e-60FFCP PHASE1:Hg19::chr6:68596698..68596715,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68596698..68596715, -
2.15e-60FFCP PHASE2:Hg19::chr6:68598534..68598555,-#_aafe90a944e339f71f5103241b4c22cbp@chr6:68598534..68598555, -
2.4e-60FFCP PHASE2:Hg19::chr19:695494..695510,-#_188392a4d9e355bf221f43a4f759f009p3@PRSS57
2.4e-60FFCP PHASE1:Hg19::chr19:695494..695510,-#_188392a4d9e355bf221f43a4f759f009p3@PRSS57
5.98e-60FFCP PHASE2:Hg19::chr6:68599042..68599067,-#_7c0ae6a1d9ff45b7059dbee72c19ba09p1@uc003pes.1, p1@uc003pet.1
5.98e-60FFCP PHASE1:Hg19::chr6:68599042..68599067,-#_7c0ae6a1d9ff45b7059dbee72c19ba09p1@uc003pes.1, p1@uc003pet.1
1.21e-59FFCP PHASE2:Hg19::chr11:33913475..33913549,-#_99b606b685c616b429973e3d35510aa0p5@LMO2
1.21e-59FFCP PHASE1:Hg19::chr11:33913475..33913549,-#_99b606b685c616b429973e3d35510aa0p5@LMO2
1.58e-59FFCP PHASE2:Hg19::chr6:135501708..135501716,+#_b8123b60492bcc97e43edbc77361535dp@chr6:135501708..135501716, +
1.58e-59FFCP PHASE1:Hg19::chr6:135501708..135501716,+#_b8123b60492bcc97e43edbc77361535dp@chr6:135501708..135501716, +
1.6e-59FFCP PHASE2:Hg19::chrX:65146038..65146063,-#_0af9d4bed3f3740cb864e7e512e2630cp@chrX:65146038..65146063, -
1.6e-59FFCP PHASE1:Hg19::chrX:65146038..65146063,-#_0af9d4bed3f3740cb864e7e512e2630cp@chrX:65146038..65146063, -
2.35e-59FFCP PHASE1:Hg19::chr8:130560794..130560810,-#_b3cb338bb44c16b3fe5e4f0597215a4fp@chr8:130560794..130560810, -
2.35e-59FFCP PHASE2:Hg19::chr8:130560794..130560810,-#_b3cb338bb44c16b3fe5e4f0597215a4fp@chr8:130560794..130560810, -
2.1e-58FFCP PHASE2:Hg19::chr8:130560752..130560768,-#_7d3ecd07304adca936492b4038ae4c38p@chr8:130560752..130560768, -
2.1e-58FFCP PHASE1:Hg19::chr8:130560752..130560768,-#_7d3ecd07304adca936492b4038ae4c38p@chr8:130560752..130560768, -
3.28e-58FFCP PHASE2:Mm9::chr11:104171122..104171127,+#_8a8d0c934e883278e89abfeeb8aed2dfp@chr11:104171122..104171127, +
3.28e-58FFCP PHASE1:Mm9::chr11:104171122..104171127,+#_8a8d0c934e883278e89abfeeb8aed2dfp@chr11:104171122..104171127, +
9.68e-58FFCP PHASE2:Hg19::chr6:68598984..68598997,-#_5898f8b18fa99e8434d573803c425453p2@uc003pes.1, p2@uc003pet.1
9.68e-58FFCP PHASE1:Hg19::chr6:68598984..68598997,-#_5898f8b18fa99e8434d573803c425453p2@uc003pes.1, p2@uc003pet.1
9.63e-57FFCP PHASE2:Hg19::chr6:68593520..68593534,-#_6c18fdc2a4f16a466c67006d34e33254p@chr6:68593520..68593534, -
9.63e-57FFCP PHASE1:Hg19::chr6:68593520..68593534,-#_6c18fdc2a4f16a466c67006d34e33254p@chr6:68593520..68593534, -
1.09e-56FFCP PHASE2:Hg19::chr6:68596343..68596355,-#_7e5f1d8628ac340812353dd6506a8204p@chr6:68596343..68596355, -
1.09e-56FFCP PHASE2:Hg19::chr6:68596783..68596797,-#_7e5f1d8628ac340812353dd6506a8204p@chr6:68596783..68596797, -
1.09e-56FFCP PHASE1:Hg19::chr6:68596343..68596355,-#_7e5f1d8628ac340812353dd6506a8204p@chr6:68596343..68596355, -
1.09e-56FFCP PHASE1:Hg19::chr6:68596783..68596797,-#_7e5f1d8628ac340812353dd6506a8204p@chr6:68596783..68596797, -
4.1e-55FFCP PHASE2:Hg19::chr6:68593206..68593218,-#_a2aeff6d2fb0e8eb9e207b3e53b12d8ap@chr6:68593206..68593218, -
4.1e-55FFCP PHASE1:Hg19::chr6:68593206..68593218,-#_a2aeff6d2fb0e8eb9e207b3e53b12d8ap@chr6:68593206..68593218, -
1.62e-54FFCP PHASE1:Hg19::chr12:58329689..58329704,-#_0d13799af4f6aef077f5afe06f36ad5fp4@ENST00000547492
1.62e-54FFCP PHASE2:Hg19::chr12:58329689..58329704,-#_0d13799af4f6aef077f5afe06f36ad5fp4@ENST00000547492
2.35e-54FFCP PHASE1:Hg19::chr3:53231298..53231310,+#_2c3e2cfe5f2b489325141f108844c723p@chr3:53231298..53231310, +
2.35e-54FFCP PHASE2:Hg19::chr3:53231298..53231310,+#_2c3e2cfe5f2b489325141f108844c723p@chr3:53231298..53231310, +
3.68e-54FFCP PHASE1:Hg19::chr3:18020982..18021001,+#_ae9b3d6638504ee2a258f3e63d0114abp@chr3:18020982..18021001, +
3.68e-54FFCP PHASE2:Hg19::chr3:18020982..18021001,+#_ae9b3d6638504ee2a258f3e63d0114abp@chr3:18020982..18021001, +
1.18e-53FFCP PHASE2:Hg19::chr11:17297872..17297908,+#_82879a884ca84ad0d3381d27452ff722p7@NUCB2
1.18e-53FFCP PHASE1:Hg19::chr11:17297872..17297908,+#_82879a884ca84ad0d3381d27452ff722p7@NUCB2

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