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Coexpression cluster:C4832

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Full id: C4832_thyroid_extraskeletal_neuroectodermal_peripheral_smallcell_Hepatic_Renal



Phase1 CAGE Peaks

Hg19::chr9:80263194..80263205,-p8@GNA14
Hg19::chr9:80263220..80263246,-p1@GNA14
Hg19::chr9:80263254..80263272,-p4@GNA14


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism6.82e-50115
anatomical cluster6.57e-26286
anatomical conduit1.98e-25241
neural tube2.64e-2457
neural rod2.64e-2457
future spinal cord2.64e-2457
neural keel2.64e-2457
tube1.71e-23194
regional part of brain2.08e-2159
central nervous system1.55e-2082
neurectoderm2.21e-2090
regional part of forebrain6.85e-2041
forebrain6.85e-2041
future forebrain6.85e-2041
neural plate2.26e-1986
presumptive neural plate2.26e-1986
anterior neural tube4.73e-1942
regional part of nervous system1.19e-1894
nervous system1.19e-1894
brain1.38e-1769
future brain1.38e-1769
gray matter3.33e-1734
brain grey matter3.33e-1734
telencephalon9.55e-1734
regional part of telencephalon2.33e-1633
cerebral hemisphere4.44e-1632
multi-cellular organism2.64e-15659
anterior region of body6.44e-14129
craniocervical region6.44e-14129
pre-chordal neural plate2.35e-1361
ectoderm2.80e-13173
presumptive ectoderm2.80e-13173
head3.78e-13123
ectoderm-derived structure1.92e-12169
regional part of cerebral cortex2.37e-1222
cerebral cortex1.61e-1125
pallium1.61e-1125
embryo2.00e-11612
splanchnic layer of lateral plate mesoderm5.04e-1184
multi-tissue structure5.88e-11347
neocortex7.17e-1120
epithelium8.61e-11309
cell layer1.12e-10312
anatomical system4.10e-10625
anatomical group5.48e-10626
embryonic structure5.03e-09605
developing anatomical structure5.03e-09605
germ layer1.06e-08604
embryonic tissue1.06e-08604
presumptive structure1.06e-08604
epiblast (generic)1.06e-08604
circulatory system5.70e-08113
organ part5.84e-08219
organism subdivision8.49e-08365
basal ganglion1.17e-079
nuclear complex of neuraxis1.17e-079
aggregate regional part of brain1.17e-079
collection of basal ganglia1.17e-079
cerebral subcortex1.17e-079
nucleus of brain2.13e-079
neural nucleus2.13e-079
cardiovascular system2.38e-07110
vessel2.79e-0769
epithelial tube3.00e-07118
primary circulatory organ5.03e-0727
compound organ5.42e-0769
organ9.18e-07511


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.