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Coexpression cluster:C3164

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Full id: C3164_pharyngeal_temporal_occipital_Hepatocyte_rectum_optic_brain



Phase1 CAGE Peaks

Hg19::chr11:58939589..58939610,+p3@DTX4
Hg19::chr11:58939616..58939668,+p1@DTX4
Hg19::chr11:58939673..58939697,+p2@DTX4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism3.67e-22115
neural tube1.51e-1857
neural rod1.51e-1857
future spinal cord1.51e-1857
neural keel1.51e-1857
central nervous system3.46e-1682
neural plate1.28e-1586
presumptive neural plate1.28e-1586
regional part of brain5.11e-1559
anterior neural tube4.14e-1442
neurectoderm4.54e-1490
regional part of forebrain4.78e-1441
forebrain4.78e-1441
future forebrain4.78e-1441
subdivision of digestive tract2.67e-13129
endodermal part of digestive tract2.67e-13129
regional part of nervous system3.24e-1394
nervous system3.24e-1394
organ part5.12e-13219
endoderm-derived structure8.10e-13169
endoderm8.10e-13169
presumptive endoderm8.10e-13169
telencephalon9.47e-1334
gray matter1.86e-1234
brain grey matter1.86e-1234
regional part of telencephalon2.83e-1233
brain4.97e-1269
future brain4.97e-1269
ectoderm-derived structure6.66e-12169
cerebral hemisphere8.28e-1232
digestive system8.39e-12155
digestive tract8.39e-12155
primitive gut8.39e-12155
pre-chordal neural plate1.69e-1161
ectoderm4.65e-11173
presumptive ectoderm4.65e-11173
regional part of cerebral cortex1.20e-1022
cerebral cortex3.07e-1025
pallium3.07e-1025
organ5.54e-10511
neocortex5.65e-1020
head6.67e-10123
anterior region of body1.94e-09129
craniocervical region1.94e-09129
multi-tissue structure2.00e-09347
mixed endoderm/mesoderm-derived structure5.81e-09130
gastrointestinal system3.41e-0835
embryo4.21e-07612


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.