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Coexpression cluster:C1101

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Full id: C1101_testis_cerebellum_parietal_medial_occipital_middle_pituitary



Phase1 CAGE Peaks

Hg19::chr10:102279586..102279637,-p2@SEC31B
Hg19::chr10:94050794..94050818,-p2@CPEB3
Hg19::chr10:94050820..94050868,-p1@CPEB3
Hg19::chr15:76352095..76352145,-p2@NRG4
Hg19::chr18:76829258..76829280,+p3@ATP9B
Hg19::chr3:197476560..197476577,-p5@KIAA0226
Hg19::chr3:197476580..197476657,-p2@KIAA0226


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0015917aminophospholipid transport0.0261368651156931
GO:0004012phospholipid-translocating ATPase activity0.0478773993503692
GO:0015247aminophospholipid transporter activity0.0478773993503692
GO:0015914phospholipid transport0.0478773993503692



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
leukocyte6.58e-07140
lymphocyte9.91e-0753
common lymphoid progenitor9.91e-0753
Uber Anatomy
Ontology termp-valuen
adult organism2.72e-53115
neural tube4.10e-2857
neural rod4.10e-2857
future spinal cord4.10e-2857
neural keel4.10e-2857
central nervous system6.16e-2582
regional part of brain7.70e-2459
brain2.23e-2369
future brain2.23e-2369
regional part of nervous system1.13e-2294
nervous system1.13e-2294
anterior neural tube3.83e-2242
regional part of forebrain9.91e-2241
forebrain9.91e-2241
future forebrain9.91e-2241
neurectoderm5.78e-1890
gray matter1.07e-1734
brain grey matter1.07e-1734
telencephalon1.13e-1734
neural plate1.90e-1786
presumptive neural plate1.90e-1786
regional part of telencephalon4.82e-1733
cerebral hemisphere1.45e-1632
regional part of cerebral cortex1.95e-1522
neocortex2.83e-1420
cerebral cortex1.53e-1225
pallium1.53e-1225
anterior region of body4.42e-12129
craniocervical region4.42e-12129
pre-chordal neural plate5.90e-1161
head1.20e-10123
ectoderm1.68e-10173
presumptive ectoderm1.68e-10173
ectoderm-derived structure5.24e-10169
posterior neural tube3.53e-0715
chordal neural plate3.53e-0715


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.