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Coexpression cluster:C3941

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Full id: C3941_lung_synovial_testis_small_large_gall_maxillary



Phase1 CAGE Peaks

Hg19::chr1:223101757..223101776,+p3@DISP1
Hg19::chr1:223101804..223101818,+p5@DISP1
Hg19::chr1:223101832..223101847,+p4@DISP1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism7.81e-38115
regional part of nervous system1.20e-1594
nervous system1.20e-1594
central nervous system2.37e-1582
neural tube7.07e-1557
neural rod7.07e-1557
future spinal cord7.07e-1557
neural keel7.07e-1557
regional part of brain1.78e-1459
neurectoderm5.02e-1390
brain6.80e-1369
future brain6.80e-1369
neural plate4.12e-1286
presumptive neural plate4.12e-1286
regional part of forebrain3.37e-1141
forebrain3.37e-1141
future forebrain3.37e-1141
anterior neural tube1.17e-1042
telencephalon1.61e-1034
multi-tissue structure1.93e-10347
gray matter2.08e-1034
brain grey matter2.08e-1034
regional part of telencephalon3.79e-1033
cerebral hemisphere1.28e-0932
organ segment2.48e-0797
pre-chordal neural plate2.50e-0761
regional part of cerebral cortex2.62e-0722
larynx2.92e-079
embryo3.57e-07612
primordium4.69e-07168
multi-cellular organism5.96e-07659
upper respiratory tract7.11e-0719
organ9.43e-07511
anatomical cluster9.95e-07286


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.