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Coexpression cluster:C1067

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Full id: C1067_ductus_salivary_smooth_submaxillary_medial_parotid_seminal



Phase1 CAGE Peaks

Hg19::chr1:239549856..239549887,+p1@CHRM3
Hg19::chr1:239549889..239549900,+p5@CHRM3
Hg19::chr1:239549933..239549960,+p2@CHRM3
Hg19::chr1:239549963..239549974,+p6@CHRM3
Hg19::chr1:239550009..239550033,+p4@CHRM3
Hg19::chr1:239550209..239550229,+p8@CHRM3
Hg19::chr1:239550243..239550304,+p3@CHRM3
Hg19::chr1:239872062..239872067,+p@chr1:239872062..239872067
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism1.14e-40115
central nervous system5.91e-3582
regional part of nervous system4.88e-3394
nervous system4.88e-3394
neural tube1.63e-2957
neural rod1.63e-2957
future spinal cord1.63e-2957
neural keel1.63e-2957
brain1.86e-2869
future brain1.86e-2869
anterior neural tube2.49e-2842
regional part of forebrain3.41e-2841
forebrain3.41e-2841
future forebrain3.41e-2841
neural plate2.18e-2686
presumptive neural plate2.18e-2686
telencephalon9.81e-2534
gray matter1.53e-2434
brain grey matter1.53e-2434
neurectoderm1.59e-2490
cerebral hemisphere2.48e-2432
regional part of telencephalon6.48e-2433
regional part of brain1.24e-2359
pre-chordal neural plate4.17e-2361
regional part of cerebral cortex5.89e-2022
cerebral cortex8.61e-2025
pallium8.61e-2025
ectoderm-derived structure9.62e-19169
neocortex2.00e-1820
head2.71e-18123
anterior region of body2.98e-18129
craniocervical region2.98e-18129
ectoderm7.15e-18173
presumptive ectoderm7.15e-18173
organ1.16e-11511
multi-tissue structure1.38e-08347
organism subdivision2.32e-08365
multi-cellular organism2.82e-08659
embryo3.63e-08612
temporal lobe6.19e-087
anatomical group1.94e-07626
anatomical system3.00e-07625
gastrointestinal system4.72e-0735
basal ganglion8.23e-079
nuclear complex of neuraxis8.23e-079
aggregate regional part of brain8.23e-079
collection of basal ganglia8.23e-079
cerebral subcortex8.23e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.