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{{CL
{{CL
|id=CL:0000786
|alt_id=
|name=plasma cell
|namespace=cell;;efo
|def="A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin." [GO_REF:0000031, GOC:add, ISBN:0721601464, ISBN:0781735149]
|xref=BTO:0000392;;FMA:70574
|is_a=CL:0000151;;CL:0000946
|synonym="plasmacyte" EXACT []
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin." [GO_REF:0000031, GOC:add, ISBN:0721601464, ISBN:0781735149]
|subset=
|derives_from=
|derives_from=
|develops_from=CL:0000980
|develops_from=CL:0000980
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000786
|is_a=CL:0000946
|is_obsolete=
|located_in=
|located_in=
|name=plasma cell
|namespace=cell;;efo
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="plasmacyte" EXACT []
|union_of=
|xref=BTO:0000392;;FMA:70574
}}
}}

Revision as of 10:21, 12 September 2014

Name:plasma cell
Namespace:cell;;efo
Definition:"A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin." [GO_REF:0000031, GOC:add, ISBN:0721601464, ISBN:0781735149]
Xrefs:
links:

BTO:0000392

FMA:70574
Synonyms: "plasmacyte" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000946(antibody secreting cell)
develops_from:CL:0000980(plasmablast)



Children


is a:FF:10840-111E3 (plasma cell leukemia cell line:ARH-77)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000786 (plasma cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.42e-195FFCP PHASE2:Hg19::chr6:164466441..164466449,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:164466441..164466449, +
5.42e-195FFCP PHASE1:Hg19::chr5:114291872..114291873,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr5:114291872..114291873, +
5.42e-195FFCP PHASE2:Hg19::chr3:168337915..168337930,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:168337915..168337930, -
5.42e-195FFCP PHASE2:Hg19::chr21:20752617..20752622,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20752617..20752622, -
5.42e-195FFCP PHASE1:Hg19::chr6:164466345..164466352,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:164466345..164466352, +
5.42e-195FFCP PHASE1:Hg19::chr3:6686484..6686491,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:6686484..6686491, +
5.42e-195FFCP PHASE1:Hg19::chr17:76471163..76471166,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr17:76471163..76471166, +
5.42e-195FFCP PHASE1:Hg19::chr3:168236611..168236612,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:168236611..168236612, -
5.42e-195FFCP PHASE1:Hg19::chr21:20752389..20752420,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20752389..20752420, -
5.42e-195FFCP PHASE2:Hg19::chr3:158747347..158747353,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:158747347..158747353, +
5.42e-195FFCP PHASE2:Hg19::chr1:101853882..101853891,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr1:101853882..101853891, -
5.42e-195FFCP PHASE1:Hg19::chr12:40953942..40953946,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr12:40953942..40953946, +
5.42e-195FFCP PHASE1:Hg19::chr3:79363599..79363606,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:79363599..79363606, +
5.42e-195FFCP PHASE2:Hg19::chr2:77746703..77746711,-#_325ec1d385ac84dbe8fe323bf05da8c1p9@LRRTM4
5.42e-195FFCP PHASE2:Hg19::chr6:166581590..166581596,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:166581590..166581596, +
5.42e-195FFCP PHASE1:Hg19::chr21:20867728..20867731,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20867728..20867731, -
5.42e-195FFCP PHASE1:Hg19::chr4:3881462..3881469,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr4:3881462..3881469, -
5.42e-195FFCP PHASE2:Hg19::chr12:40953942..40953946,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr12:40953942..40953946, +
5.42e-195FFCP PHASE1:Hg19::chr6:164466441..164466449,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:164466441..164466449, +
5.42e-195FFCP PHASE1:Hg19::chr3:168337915..168337930,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:168337915..168337930, -
5.42e-195FFCP PHASE1:Hg19::chr21:20752617..20752622,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20752617..20752622, -
5.42e-195FFCP PHASE1:Hg19::chr10:56410468..56410499,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr10:56410468..56410499, -
5.42e-195FFCP PHASE2:Hg19::chr8:128270027..128270033,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr8:128270027..128270033, -
5.42e-195FFCP PHASE1:Hg19::chr6:166581583..166581586,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:166581583..166581586, +
5.42e-195FFCP PHASE2:Hg19::chr17:76471146..76471155,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr17:76471146..76471155, +
5.42e-195FFCP PHASE1:Hg19::chr3:158747347..158747353,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:158747347..158747353, +
5.42e-195FFCP PHASE1:Hg19::chr1:101853882..101853891,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr1:101853882..101853891, -
5.42e-195FFCP PHASE2:Hg19::chr3:178947187..178947192,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:178947187..178947192, +
5.42e-195FFCP PHASE2:Hg19::chr5:88646759..88646764,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr5:88646759..88646764, +
5.42e-195FFCP PHASE2:Hg19::chr1:17349613..17349631,-#_325ec1d385ac84dbe8fe323bf05da8c1p8@SDHB
5.42e-195FFCP PHASE2:Hg19::chr17:76475275..76475285,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr17:76475275..76475285, -
5.42e-195FFCP PHASE2:Hg19::chr14:106829914..106829921,-#_325ec1d385ac84dbe8fe323bf05da8c1p1@HM996258, p1@HM996415, p1@HM996438
5.42e-195FFCP PHASE2:Hg19::chr2:77581116..77581120,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr2:77581116..77581120, -
5.42e-195FFCP PHASE2:Hg19::chr7:86415255..86415288,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr7:86415255..86415288, +
5.42e-195FFCP PHASE2:Hg19::chr6:164466325..164466331,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:164466325..164466331, +
5.42e-195FFCP PHASE2:Hg19::chr2:77746775..77746779,-#_325ec1d385ac84dbe8fe323bf05da8c1p14@LRRTM4
5.42e-195FFCP PHASE2:Hg19::chr21:20747453..20747465,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20747453..20747465, -
5.42e-195FFCP PHASE1:Hg19::chr2:77746703..77746711,-#_325ec1d385ac84dbe8fe323bf05da8c1p9@LRRTM4
5.42e-195FFCP PHASE1:Hg19::chr6:166581590..166581596,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:166581590..166581596, +
5.42e-195FFCP PHASE2:Hg19::chr3:6686484..6686491,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:6686484..6686491, +
5.42e-195FFCP PHASE2:Hg19::chr17:76471163..76471166,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr17:76471163..76471166, +
5.42e-195FFCP PHASE2:Hg19::chr6:166581265..166581274,-#_325ec1d385ac84dbe8fe323bf05da8c1p5@T
5.42e-195FFCP PHASE1:Hg19::chr8:128270027..128270033,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr8:128270027..128270033, -
5.42e-195FFCP PHASE2:Hg19::chr1:17349654..17349690,-#_325ec1d385ac84dbe8fe323bf05da8c1p6@SDHB
5.42e-195FFCP PHASE1:Hg19::chr3:178947187..178947192,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:178947187..178947192, +
5.42e-195FFCP PHASE2:Hg19::chr5:114291872..114291873,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr5:114291872..114291873, +
5.42e-195FFCP PHASE2:Hg19::chr3:79363599..79363606,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:79363599..79363606, +
5.42e-195FFCP PHASE1:Hg19::chr5:88646759..88646764,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr5:88646759..88646764, +
5.42e-195FFCP PHASE1:Hg19::chr1:17349613..17349631,-#_325ec1d385ac84dbe8fe323bf05da8c1p8@SDHB
5.42e-195FFCP PHASE2:Hg19::chr6:164466345..164466352,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:164466345..164466352, +
5.42e-195FFCP PHASE2:Hg19::chr3:168236611..168236612,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr3:168236611..168236612, -
5.42e-195FFCP PHASE1:Hg19::chr12:40991131..40991149,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr12:40991131..40991149, +
5.42e-195FFCP PHASE1:Hg19::chr7:86415255..86415288,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr7:86415255..86415288, +
5.42e-195FFCP PHASE2:Hg19::chr21:20752389..20752420,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20752389..20752420, -
5.42e-195FFCP PHASE2:Hg19::chr4:3881462..3881469,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr4:3881462..3881469, -
5.42e-195FFCP PHASE1:Hg19::chr6:164466325..164466331,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:164466325..164466331, +
5.42e-195FFCP PHASE1:Hg19::chr2:77746775..77746779,-#_325ec1d385ac84dbe8fe323bf05da8c1p14@LRRTM4
5.42e-195FFCP PHASE1:Hg19::chr17:76471146..76471155,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr17:76471146..76471155, +
5.42e-195FFCP PHASE1:Hg19::chr21:20747453..20747465,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20747453..20747465, -
5.42e-195FFCP PHASE2:Hg19::chr21:20867728..20867731,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr21:20867728..20867731, -
5.42e-195FFCP PHASE2:Hg19::chr12:40991131..40991149,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr12:40991131..40991149, +
5.42e-195FFCP PHASE1:Hg19::chr6:166581265..166581274,-#_325ec1d385ac84dbe8fe323bf05da8c1p5@T
5.42e-195FFCP PHASE2:Hg19::chr10:56410468..56410499,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr10:56410468..56410499, -
5.42e-195FFCP PHASE1:Hg19::chr17:76475275..76475285,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr17:76475275..76475285, -
5.42e-195FFCP PHASE1:Hg19::chr14:106829914..106829921,-#_325ec1d385ac84dbe8fe323bf05da8c1p1@HM996258, p1@HM996415, p1@HM996438
5.42e-195FFCP PHASE1:Hg19::chr2:77581116..77581120,-#_325ec1d385ac84dbe8fe323bf05da8c1p@chr2:77581116..77581120, -
5.42e-195FFCP PHASE2:Hg19::chr6:166581583..166581586,+#_325ec1d385ac84dbe8fe323bf05da8c1p@chr6:166581583..166581586, +
5.42e-195FFCP PHASE1:Hg19::chr1:17349654..17349690,-#_325ec1d385ac84dbe8fe323bf05da8c1p6@SDHB
9.37e-99FFCP PHASE1:Hg19::chr12:126922654..126922657,+#_ba7867af22b4fd1eeec292f126b55361p@chr12:126922654..126922657, +
9.37e-99FFCP PHASE1:Hg19::chr6:130881420..130881455,-#_ba7867af22b4fd1eeec292f126b55361p@chr6:130881420..130881455, -
9.37e-99FFCP PHASE2:Hg19::chr2:101054417..101054453,+#_ba7867af22b4fd1eeec292f126b55361p@chr2:101054417..101054453, +
9.37e-99FFCP PHASE2:Hg19::chr1:90962594..90962596,-#_ba7867af22b4fd1eeec292f126b55361p@chr1:90962594..90962596, -
9.37e-99FFCP PHASE1:Hg19::chr3:178261188..178261195,-#_ba7867af22b4fd1eeec292f126b55361p@chr3:178261188..178261195, -
9.37e-99FFCP PHASE1:Hg19::chrX:18701132..18701138,-#_ba7867af22b4fd1eeec292f126b55361p@chrX:18701132..18701138, -
9.37e-99FFCP PHASE2:Hg19::chr14:106589870..106589873,-#_ba7867af22b4fd1eeec292f126b55361p@chr14:106589870..106589873, -
9.37e-99FFCP PHASE1:Hg19::chr14:106586621..106586626,-#_ba7867af22b4fd1eeec292f126b55361p3@IGHV3-13
9.37e-99FFCP PHASE2:Hg19::chr18:67696064..67696069,-#_ba7867af22b4fd1eeec292f126b55361p@chr18:67696064..67696069, -
9.37e-99FFCP PHASE2:Hg19::chr12:126922654..126922657,+#_ba7867af22b4fd1eeec292f126b55361p@chr12:126922654..126922657, +
9.37e-99FFCP PHASE1:Hg19::chr3:189839512..189839520,-#_ba7867af22b4fd1eeec292f126b55361p21@LEPREL1
9.37e-99FFCP PHASE2:Hg19::chr14:54342069..54342074,-#_ba7867af22b4fd1eeec292f126b55361p@chr14:54342069..54342074, -
9.37e-99FFCP PHASE1:Hg19::chr2:157336503..157336506,-#_ba7867af22b4fd1eeec292f126b55361p@chr2:157336503..157336506, -
9.37e-99FFCP PHASE2:Hg19::chr21:20752643..20752654,-#_ba7867af22b4fd1eeec292f126b55361p@chr21:20752643..20752654, -
9.37e-99FFCP PHASE2:Hg19::chr18:28728570..28728577,-#_ba7867af22b4fd1eeec292f126b55361p@chr18:28728570..28728577, -
9.37e-99FFCP PHASE1:Hg19::chr2:101054417..101054453,+#_ba7867af22b4fd1eeec292f126b55361p@chr2:101054417..101054453, +
9.37e-99FFCP PHASE2:Hg19::chr6:166581392..166581398,+#_ba7867af22b4fd1eeec292f126b55361p@chr6:166581392..166581398, +
9.37e-99FFCP PHASE2:Hg19::chr14:102992396..102992401,+#_ba7867af22b4fd1eeec292f126b55361p@chr14:102992396..102992401, +
9.37e-99FFCP PHASE2:Hg19::chr6:166581221..166581226,-#_ba7867af22b4fd1eeec292f126b55361p8@T
9.37e-99FFCP PHASE2:Hg19::chr3:111298881..111298895,-#_ba7867af22b4fd1eeec292f126b55361p@chr3:111298881..111298895, -
9.37e-99FFCP PHASE2:Hg19::chr7:119999940..119999943,+#_ba7867af22b4fd1eeec292f126b55361p@chr7:119999940..119999943, +
9.37e-99FFCP PHASE1:Hg19::chr1:90962594..90962596,-#_ba7867af22b4fd1eeec292f126b55361p@chr1:90962594..90962596, -
9.37e-99FFCP PHASE2:Hg19::chr5:114289920..114289928,+#_ba7867af22b4fd1eeec292f126b55361p@chr5:114289920..114289928, +
9.37e-99FFCP PHASE2:Hg19::chr3:189840223..189840229,-#_ba7867af22b4fd1eeec292f126b55361p26@LEPREL1
9.37e-99FFCP PHASE2:Hg19::chr19:36698672..36698675,-#_ba7867af22b4fd1eeec292f126b55361p@chr19:36698672..36698675, -
9.37e-99FFCP PHASE2:Hg19::chr6:130878898..130878925,+#_ba7867af22b4fd1eeec292f126b55361p@chr6:130878898..130878925, +
9.37e-99FFCP PHASE1:Hg19::chr14:106589870..106589873,-#_ba7867af22b4fd1eeec292f126b55361p@chr14:106589870..106589873, -
9.37e-99FFCP PHASE1:Hg19::chr18:67696064..67696069,-#_ba7867af22b4fd1eeec292f126b55361p@chr18:67696064..67696069, -
9.37e-99FFCP PHASE2:Hg19::chr6:166581393..166581398,-#_ba7867af22b4fd1eeec292f126b55361p6@T
9.37e-99FFCP PHASE1:Hg19::chr14:54342069..54342074,-#_ba7867af22b4fd1eeec292f126b55361p@chr14:54342069..54342074, -
9.37e-99FFCP PHASE1:Hg19::chr21:20752643..20752654,-#_ba7867af22b4fd1eeec292f126b55361p@chr21:20752643..20752654, -
9.37e-99FFCP PHASE1:Hg19::chr12:776344..776351,-#_ba7867af22b4fd1eeec292f126b55361p@chr12:776344..776351, -

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