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MCL coexpression mm9:497: Difference between revisions

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{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0004245;neprilysin activity;0.032765781590713;18675!GO:0004467;long-chain-fatty-acid-CoA ligase activity;0.032765781590713;225579!GO:0015645;fatty-acid ligase activity;0.032765781590713;225579!GO:0001676;long-chain fatty acid metabolic process;0.032765781590713;225579!GO:0016877;ligase activity, forming carbon-sulfur bonds;0.0430423622096199;225579!
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002048!1.79e-16!14;UBERON:0000117!1.79e-16!14;UBERON:0000171!1.79e-16!14;UBERON:0000170!1.79e-16!14;UBERON:0005597!1.79e-16!14;UBERON:0000118!1.79e-16!14;UBERON:0005153!1.16e-12!17;UBERON:0005178!1.16e-12!17;UBERON:0005181!1.16e-12!17;UBERON:0002224!1.16e-12!17;UBERON:0000915!1.16e-12!17;UBERON:0008947!1.16e-12!17;UBERON:0003258!1.16e-12!17;UBERON:0005157!5.02e-10!20;UBERON:0000310!1.99e-07!6;UBERON:0001443!1.99e-07!6;UBERON:0000464!8.43e-07!57
|tfbs_overrepresentation_for_novel_motifs=0.206403,0.236794,0.186933,0.671595,0.721878,0.250289,0.324772,0.460624,0.485477,0.0308722,0.288187,0.314655,0.210446,1.59914,0.120865,0,0.505674,0.105493,2.12377,2.7873,0.160516,0.0504052,0.334384,0.109412,1.06882,0.35869,0.0471703,0.267095,0.139679,2.188,2.02463,0.598971,0.104128,0.634402,0.770595,0.0584849,0.0985485,0.311629,0.290566,0.0703677,0.107883,0.259911,0.438559,0.387037,0.0283033,1.21508,0.433813,0.279902,0.0308934,0.141659,0.48979,0.381972,0.832043,0.732469,0.749094,0.341233,0.147717,0.303999,0.166653,0.339495,0.580338,0.390204,0.0681609,0.479581,0.350748,0.516415,0.880067,1.22155,0.576002,1.07689,0.173229,0.0605055,0.0113485,0.781142,0.158223,0.144279,3.00057,0.423705,0.564426,0.163487,0.479273,0.521544,0.388944,0.774743,0.671442,0.00202775,0.016756,0.297913,0.438181,1.38183,0.947651,0.676142,0.610915,1.76956,0.0836626,0.0741053,0.790304,0.613539,0.43404,1.51499,2.88337,0.59871,0.715894,0.490329,0.489372,0.259558,0.543989,0.276621,0.16693,0.161774,0.201092,0.717588,2.17768,0.292444,0.954503,0.106786,0.0221978,0.678491,0.506861,0.096357,0.786314,0.46068,0.946372,0.422901,1.00724,0.567849,0.331666,0.60459,0.8786,1.78581,0.699779,0.658263,0.850049,0.9301,2.23619,0.00977832,0.212784,0.261043,0.927716,1.74768,1.35029,0.884624,0.370659,0.608735,0.483498,0.260275,0.436593,1.7082,0.214583,0.111457,0.303478,0.00817433,0.733963,0.266555,1.65879,0.81211,0.382849,0.803531,2.47485,0.212571,0.93695,0.670634,0.568261,0.199399,1.20775,0.345769,2.21829,0.313326,0.000601576
|tfbs_overrepresentation_jaspar=MA0003.1;0.13442,MA0004.1;0.239244,MA0006.1;0.118059,MA0007.1;0.227553,MA0009.1;0.623671,MA0014.1;0.304428,MA0017.1;0.420732,MA0019.1;1.15568,MA0024.1;0.582844,MA0025.1;0.845702,MA0027.1;2.24512,MA0028.1;0.12472,MA0029.1;0.562703,MA0030.1;0.568779,MA0031.1;0.535959,MA0038.1;0.358622,MA0040.1;0.635404,MA0041.1;0.18185,MA0042.1;0.172351,MA0043.1;0.71494,MA0046.1;0.657417,MA0048.1;0.0239691,MA0050.1;0.270164,MA0051.1;0.366328,MA0052.1;0.642973,MA0055.1;1.0953,MA0056.1;0,MA0057.1;0.226212,MA0058.1;0.167504,MA0059.1;0.176308,MA0060.1;0.071412,MA0061.1;0.0877629,MA0063.1;0,MA0066.1;0.349199,MA0067.1;0.953264,MA0068.1;0.0945752,MA0069.1;0.643292,MA0070.1;0.634186,MA0071.1;0.742345,MA0072.1;0.626238,MA0073.1;0.834748,MA0074.1;0.318792,MA0076.1;0.148159,MA0077.1;0.605975,MA0078.1;0.395048,MA0081.1;0.56362,MA0083.1;0.714187,MA0084.1;1.27474,MA0087.1;0.673355,MA0088.1;1.07775,MA0089.1;0,MA0090.1;0.212772,MA0091.1;1.28859,MA0092.1;0.213012,MA0093.1;0.130107,MA0095.1;0,MA0098.1;0,MA0100.1;1.50646,MA0101.1;0.538493,MA0103.1;0.14251,MA0105.1;0.0373599,MA0106.1;0.401864,MA0107.1;0.138378,MA0108.2;0.476838,MA0109.1;0,MA0111.1;0.223614,MA0113.1;0.377232,MA0114.1;0.0864402,MA0115.1;0.717599,MA0116.1;0.117928,MA0117.1;0.686999,MA0119.1;1.03177,MA0122.1;0.705806,MA0124.1;0.901619,MA0125.1;0.830088,MA0130.1;0,MA0131.1;0.452196,MA0132.1;0,MA0133.1;0,MA0135.1;1.77281,MA0136.1;0.335579,MA0139.1;0.0558308,MA0140.1;0.30902,MA0141.1;1.47359,MA0142.1;0.522654,MA0143.1;0.391481,MA0144.1;0.0881858,MA0145.1;0.0124347,MA0146.1;0.000953111,MA0147.1;0.0952713,MA0148.1;0.252062,MA0149.1;0.18682,MA0062.2;0.0394542,MA0035.2;0.312946,MA0039.2;0.967453,MA0138.2;3.99986,MA0002.2;0.0572064,MA0137.2;0.153989,MA0104.2;0.0641853,MA0047.2;0.357963,MA0112.2;0.0599393,MA0065.2;0.0125174,MA0150.1;0.227466,MA0151.1;0,MA0152.1;0.358055,MA0153.1;0.765498,MA0154.1;0.0232776,MA0155.1;1.27441,MA0156.1;0.147567,MA0157.1;0.493416,MA0158.1;0,MA0159.1;0.332142,MA0160.1;1.30669,MA0161.1;0,MA0162.1;0.170606,MA0163.1;0.0289848,MA0164.1;0.335886,MA0080.2;0.13897,MA0018.2;0.344133,MA0099.2;0.439458,MA0079.2;1.39766,MA0102.2;1.32652,MA0258.1;0.271229,MA0259.1;0.0890842,MA0442.1;0
}}

Latest revision as of 15:24, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr14:119536766..119536773,+p@chr14:119536766..119536773
+
Mm9::chr18:58715612..58715663,+p1@Slc27a6
Mm9::chr18:58715665..58715701,+p3@Slc27a6
Mm9::chr18:58715716..58715727,+p4@Slc27a6
Mm9::chr18:58715730..58715735,+p7@Slc27a6
Mm9::chr18:58715744..58715754,+p6@Slc27a6
Mm9::chr18:58715854..58715870,+p5@Slc27a6
Mm9::chr18:58715878..58715900,+p2@Slc27a6
Mm9::chr18:58772481..58772486,+p@chr18:58772481..58772486
+
Mm9::chr1:135152659..135152676,+p@chr1:135152659..135152676
+
Mm9::chr1:135152690..135152732,+p@chr1:135152690..135152732
+
Mm9::chr1:51037934..51037949,-p@chr1:51037934..51037949
-
Mm9::chr2:172219448..172219464,+p1@Cass4
Mm9::chr8:105310531..105310551,-p@chr8:105310531..105310551
-
Mm9::chrX:153853025..153853036,-p4@Phex


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004245neprilysin activity0.032765781590713
GO:0004467long-chain-fatty-acid-CoA ligase activity0.032765781590713
GO:0015645fatty-acid ligase activity0.032765781590713
GO:0001676long-chain fatty acid metabolic process0.032765781590713
GO:0016877ligase activity, forming carbon-sulfur bonds0.0430423622096199



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
lung1.79e-1614
respiratory tube1.79e-1614
respiration organ1.79e-1614
pair of lungs1.79e-1614
lung primordium1.79e-1614
lung bud1.79e-1614
epithelial bud1.16e-1217
thoracic cavity element1.16e-1217
thoracic segment organ1.16e-1217
thoracic cavity1.16e-1217
thoracic segment of trunk1.16e-1217
respiratory primordium1.16e-1217
endoderm of foregut1.16e-1217
epithelial fold5.02e-1020
breast1.99e-076
chest1.99e-076
anatomical space8.43e-0757


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.13442
MA0004.10.239244
MA0006.10.118059
MA0007.10.227553
MA0009.10.623671
MA0014.10.304428
MA0017.10.420732
MA0019.11.15568
MA0024.10.582844
MA0025.10.845702
MA0027.12.24512
MA0028.10.12472
MA0029.10.562703
MA0030.10.568779
MA0031.10.535959
MA0038.10.358622
MA0040.10.635404
MA0041.10.18185
MA0042.10.172351
MA0043.10.71494
MA0046.10.657417
MA0048.10.0239691
MA0050.10.270164
MA0051.10.366328
MA0052.10.642973
MA0055.11.0953
MA0056.10
MA0057.10.226212
MA0058.10.167504
MA0059.10.176308
MA0060.10.071412
MA0061.10.0877629
MA0063.10
MA0066.10.349199
MA0067.10.953264
MA0068.10.0945752
MA0069.10.643292
MA0070.10.634186
MA0071.10.742345
MA0072.10.626238
MA0073.10.834748
MA0074.10.318792
MA0076.10.148159
MA0077.10.605975
MA0078.10.395048
MA0081.10.56362
MA0083.10.714187
MA0084.11.27474
MA0087.10.673355
MA0088.11.07775
MA0089.10
MA0090.10.212772
MA0091.11.28859
MA0092.10.213012
MA0093.10.130107
MA0095.10
MA0098.10
MA0100.11.50646
MA0101.10.538493
MA0103.10.14251
MA0105.10.0373599
MA0106.10.401864
MA0107.10.138378
MA0108.20.476838
MA0109.10
MA0111.10.223614
MA0113.10.377232
MA0114.10.0864402
MA0115.10.717599
MA0116.10.117928
MA0117.10.686999
MA0119.11.03177
MA0122.10.705806
MA0124.10.901619
MA0125.10.830088
MA0130.10
MA0131.10.452196
MA0132.10
MA0133.10
MA0135.11.77281
MA0136.10.335579
MA0139.10.0558308
MA0140.10.30902
MA0141.11.47359
MA0142.10.522654
MA0143.10.391481
MA0144.10.0881858
MA0145.10.0124347
MA0146.10.000953111
MA0147.10.0952713
MA0148.10.252062
MA0149.10.18682
MA0062.20.0394542
MA0035.20.312946
MA0039.20.967453
MA0138.23.99986
MA0002.20.0572064
MA0137.20.153989
MA0104.20.0641853
MA0047.20.357963
MA0112.20.0599393
MA0065.20.0125174
MA0150.10.227466
MA0151.10
MA0152.10.358055
MA0153.10.765498
MA0154.10.0232776
MA0155.11.27441
MA0156.10.147567
MA0157.10.493416
MA0158.10
MA0159.10.332142
MA0160.11.30669
MA0161.10
MA0162.10.170606
MA0163.10.0289848
MA0164.10.335886
MA0080.20.13897
MA0018.20.344133
MA0099.20.439458
MA0079.21.39766
MA0102.21.32652
MA0258.10.271229
MA0259.10.0890842
MA0442.10