FFCP PHASE1:Hg19::chr15:67835216..67835227,+: Difference between revisions
From FANTOM5_SSTAR
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
{{FFCP | {{FFCP|DPIdataset=robustDPI|EntrezGene=5607|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=gencodeV16_protein_coding|HGNC=6845|TSSclassifier=S|UniProt=Q13163|association_with_transcript=169bp_to_ENST00000178640_5end|description=CAGE_peak_6_at_MAP2K5_5end|id=chr15:67835216..67835227,+|ontology_enrichment_celltype=|ontology_enrichment_celltype_v019=CL:0002564;6.56e-08;3|ontology_enrichment_celltype_v019_2=CL:0002564,8.29e-08,3|ontology_enrichment_development_v019=UBERON:0005754;4.66e-21;1!UBERON:0007297;3.18e-11;2!UBERON:0006215;6.56e-08;3|ontology_enrichment_disease=|ontology_enrichment_disease_v019=|ontology_enrichment_disease_v019_2=|ontology_enrichment_uberon=|ontology_enrichment_uberon_v019=UBERON:0000998;4.66e-21;1!UBERON:0006868;4.66e-21;1!UBERON:0002771;1.82e-11;2!UBERON:0002242;6.56e-08;3!UBERON:0002114;6.56e-08;2!UBERON:0006947;6.56e-08;3!UBERON:0004054;6.56e-08;3|ontology_enrichment_uberon_v019_2=UBERON:0000998,4.22e-21,1;UBERON:0006868,4.22e-21,1;UBERON:0002771,1.82e-11,2;UBERON:0000080,1.01e-09,9;UBERON:0002120,1.01e-09,9;UBERON:0004875,1.01e-09,9;UBERON:0005721,1.01e-09,9;UBERON:0005754,1.01e-09,9;UBERON:0007297,1.01e-09,9;UBERON:0004876,4.04e-08,11;UBERON:0002114,5.93e-08,2;UBERON:0006947,6.34e-08,3;UBERON:0004054,6.34e-08,3;UBERON:0002242,8.29e-08,3;UBERON:0003068,8.29e-08,3;UBERON:0002328,8.29e-08,3;UBERON:0004880,8.29e-08,3;UBERON:0003887,1.62e-07,12|phase1_expression=0.181678379270557,0.642301571672949,0,0,0,0,0,0,0,0,0,0.218441372130172,0.263766978228454,0,0,1.34465029290355,0,0,0,0,0.204000691244253,0,0,0,0.125542639594803,0.305653622991805,0,0,0,0.383829398097213,0,0,0,0,0,0,0,0,0.200544447470142,0.217010870715852,0.447830948479849,0,0,0.290796477559129,0.377875943688809,0.485168122375632,0,0.411167888021826,0,0,0.256160706529101,0,0,0,0,0.376484679085209,0.545812300115692,0,0.306083892370903,0,0.639337125799041,0,0,0,0,0,0,0,0,0.434377689410233,0,0,0,0.211255286311942,0.212604299965044,0,0,0,0.32145117339416,0.285012743741249,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.205601498999509,0.167186495390678,0,0,0,0.334231370655521,0,0,0,0,0,0,0,0,0,0.535081656179426,0,0.113309342697566,0.383220493601921,0,0.253019692019503,0,0,0,0,0.127986611154418,0,0.236777252044017,0,0,0,0,0,0,0,0,0,0,0,0.486634870302636,0.189069634328136,0,0,0,0,0,0,0.174129737299267,0,0,0,0,0,0,0,0,0.419499436209906,0,0,0,0,0,0,0,0.24406205754817,0,0.81014194788176,0.17859945656816,0,0,0,0,0,0,0,0,0.496971951695318,0.12663051166458,0,0,0,0.560677600142307,0,0,0,0,0.163461903113459,0,0.576175924479999,0,0,0,0.149448680551801,0.117434498643765,0,0.140450806702248,0.204154171254893,0,0.413303124703062,1.18800285728205,0,0,0,0,0.250237039743928,0,0,0.612975591598039,0.45071417671979,0,0,0,0,0,0.103052529238439,0,0.18611685633159,0,0,0,0.0920498986422993,0,0,0.201504196455281,0.169560592310488,0,0,0,0.121973706129595,0.132529768321485,0.116193942869518,0.207322110030741,0,0,0,0,0,0.464367928031979,0,0,0,0.241011029883482,0,0.217879444092406,0,0,0,0,0,0,0,0,1.26755034821831,0,0,0,0.122988438543114,0,0,0,0,0.0925884451585296,0,0,0,0,0,0.144366447761074,0,0,0,0,0,0.234004265139238,0.148631162288728,0,0,0,0.0895585227028483,0.290633938513962,0,0,0.088048434013226,0,0,0.37872730027914,0.063497894292169,0,0,0,0.205654985406647,0,0.285826432630578,0.112131084345361,0,0,0.129271715757778,0,0,0,0,0,0,0.266422179016099,0.142977993658148,0,0,0,0,0,0,0,0.099972991182057,0,0,2.10833939483032,0,0,0,0,0.410952645100767,0.179060963239896,0,0,0.215627574859517,0.256686072559497,0,0,0,0.167516265334349,0,0.749007023947182,0,0,0.24538298343828,1.00034104211935,0,0.415941723061614,0.713715955188647,0.315404830067869,0.35142424497814,0.300946099727719,0,0,0,0,0.260650843404249,0,0.343143423810856,0,0.647142602455851,0.106727557803444,0,0,0,0.248107807818777,0,0,0.128139149255701,0,0.160853921143607,0,0.308419387605311,0,0,0,0.116210378459959,0,0,0.0920809889358963,0.114814448164607,0,0.393373244878272,0,0,0,0,0.105551628892876,1.13733384070897,0,0,0,0,0,0,0,0,0,0,0,0,0.325378394664303,0,0,0,0,0.650060246036521,0,0.096670718292122,0.154048617114644,0,0.275673144969061,0.107420244868274,0,0.426133137080504,0.178064071293475,0,0.384380134730212,0,0.4046311234222,0.464845549297286,0.31481234683064,0,0,0,0,0.18532421910392,0,0,0.316379424718726,0,0,0,0,0,0,0.54907405947211,0,0,0,0,0.48763373908959,0,0,0.136499911407986,0.282810863907425,0,0.551365343546124,0,0.438450885253763,0,0,0,0,0,0,0,0,0,0.633322905892992,0,0.379473173765715,0,0,0,0,0.188287601553558,0,0,0.886860307073351,0,0,0,0,0,0,0,0,0.79312517629427,0.213648142254946,0,0,0,0.144269212976445,0,0,0,0,0.846694330895531,0.649243880549111,0.280797178113459,0,0.156679895773023,0,0,0.1605880751037,0.201799707191048,0,0,0,0,0.166849141711909,0.390776190804081,0,0,0,0,0,0,0.293016358543788,0.242721043499027,0.111443384277478,0,0,0,0,0,0.703347082052564,0,0,0.211125408127993,0,0.552567831062295,0,0,0.123084805461069,0,0.0898683511473268,0,0.511572370226872,0.197286811273867,0,0,0.969332746095218,0.0927680981618513,0,0.260427761085233,0,0,0,0.254253650292766,0,0,0.291604613383254,0.347249989866585,0,0.120596438625408,1.52581736317083,0.663475559587348,0,0,0,0,0.0769502585037971,0.113942055847001,0.23056390438806,0.179515288819544,0.325942115766024,0.31900115973192,0.274792780205587,0,0,0,0.166211681900156,0.225595660617181,0,0.167821586975843,0,0,0.421996129056054,0,0,0,0,0,0,0,0,0.104421949505455,0,0.802577647298789,0.234264445725339,0.364909578431332,0,0,0,0,0.61214552326098,0.189559738885464,0,0.207376382794494,0,0.330991955875499,0,0,0,0,0.173559738335131,0.0979923974143777,0,0.698906672968121,0,0.19351266257817,0.584714536689484,0.164230914106418,0.193978032976839,0,0,0,0.19871461170299,0.0633107959558787,0,0.240476460754601,0.640358984218058,0,0,0.114536596165916,0.171594997861965,0,0.248505071130865,0,0,0,0,0.577901179803038,0,0.273810757783986,0,0,0,0,0.229160424011684,0,0.199679000498991,0,0,0.0671834724867263,0,0,0,0.247247575143499,0,0,0,0.795229689809303,0.408610218334727,0.160753148465019,0.137539436597234,0.83088067605837,0,0,0.121499113316049,0.335434687599266,0,0.0524545881349981,0,0,0.191915197319445,0,0.662091970365432,0,0,0,0.326587360109409,0,0,0,0.226624183040251,0,0,0,0.26446520348538,0,0,0,0.157204305099666,0,0.496166021811951,0,0.243585196761792,0,0,0,0,0.327872630709804,0.157054096250234,0,5.00307686098049,0.3755727921195,0,0,0.0620964029413835,0.415045904808692,0.124980407962107,0.151649117541648,0,0.235265819698172,0,0,0.149254802886874,0,0,0,0.251567901752575,0,0.228840068396924,0,0,0.147855149989634,0,0,0,0,0,0.521745061811734,0,0,0,0,0,0,0,0.400027764663154,0,0,0,0,0,0.260994291965212,0.453411851024545,0,0,0,0,0.219284049578707,0,0,0,0,0.345430341731199,0,0,0.194860308839388,0,0.163565394255844,0.655219697692825,0,0,0,0,0,0,0.368211900503681,0,0,0.127894371303652,0,0,0,0,0,0.371807292777007,0.558644917973244,0,0.315446980005013,0,0,0,0.192687675289379,0,0.478901577171454,0.205116364240755,0.504143392443436,0,0,0,0,0,0.366857197043358,0,0.381382095467167,0,0.397832444232549,0.225630985047772,0,0,0,0.327543835020193,0.147856086217045,0.270150338473579,0.781078098613847,0.413373593002368,0,0,0,0.496211178389294,0.527613733078862,0,0,0,0.606965604236632,0,0,0,0.171488009437418,0.0679697329768317,0.131545547125698,0.118193840883968,0,0,0.785577949580009,0,0,0.215927591218621,0,0.285906176706625,0.158013611732727,0,0,0,0.207216164163037,0.3414369541879,0,0,0.118332000730565,0.0852134047591577,1.27016115057279,0,0,0,0,0.098150233615243,0.121917924982269,0,0,0,0,0,0.397901550322736,0.118920090777569,0,0.109940516745429,0,0,0,0,0.245148321753905,0,0.981542335574726,0,0.4226557275834,0,0,0,0,0.178553938605658,0,0.160482733378337,0.730336388246517,0.458729283404541,0.143339583151451,0.157771562193185,0.203974470572744,1.30905207102113,0,0.743990036333503,0.462175628631418,0,0.252332849670158,0.109265571963696,0.506794004045748,0,0,0.0918948995348449,0.250707539292375,0.0757786982182394,0,0,0.103432995861895,0.639701945702943,0.714193294391221,0.322944549180031,0,0,0,0,0.217716747896961,0,0,0,0,0.0814032686109745,0,0,0.0898252021065869,0,0.366724332548599,0.406896178315738,0,0,0|short_description=p6@MAP2K5}} | ||
|DPIdataset=robustDPI | |||
|EntrezGene=5607 | |||
|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=gencodeV16_protein_coding | |||
|HGNC=6845 | |||
|TSSclassifier=S | |||
|UniProt=Q13163 | |||
|association_with_transcript=169bp_to_ENST00000178640_5end | |||
|description=CAGE_peak_6_at_MAP2K5_5end | |||
|id=chr15:67835216..67835227,+ | |||
|ontology_enrichment_celltype= | |||
|ontology_enrichment_celltype_v019=CL:0002564;6.56e-08;3 | |||
|ontology_enrichment_celltype_v019_2=CL:0002564,8.29e-08,3 | |||
|ontology_enrichment_development_v019=UBERON:0005754;4.66e-21;1!UBERON:0007297;3.18e-11;2!UBERON:0006215;6.56e-08;3 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_disease_v019= | |||
|ontology_enrichment_disease_v019_2= | |||
|ontology_enrichment_uberon= | |||
|ontology_enrichment_uberon_v019=UBERON:0000998;4.66e-21;1!UBERON:0006868;4.66e-21;1!UBERON:0002771;1.82e-11;2!UBERON:0002242;6.56e-08;3!UBERON:0002114;6.56e-08;2!UBERON:0006947;6.56e-08;3!UBERON:0004054;6.56e-08;3 | |||
|ontology_enrichment_uberon_v019_2=UBERON:0000998,4.22e-21,1;UBERON:0006868,4.22e-21,1;UBERON:0002771,1.82e-11,2;UBERON:0000080,1.01e-09,9;UBERON:0002120,1.01e-09,9;UBERON:0004875,1.01e-09,9;UBERON:0005721,1.01e-09,9;UBERON:0005754,1.01e-09,9;UBERON:0007297,1.01e-09,9;UBERON:0004876,4.04e-08,11;UBERON:0002114,5.93e-08,2;UBERON:0006947,6.34e-08,3;UBERON:0004054,6.34e-08,3;UBERON:0002242,8.29e-08,3;UBERON:0003068,8.29e-08,3;UBERON:0002328,8.29e-08,3;UBERON:0004880,8.29e-08,3;UBERON:0003887,1.62e-07,12 | |||
|phase1_expression=0.181678379270557,0.642301571672949,0,0,0,0,0,0,0,0,0,0.218441372130172,0.263766978228454,0,0,1.34465029290355,0,0,0,0,0.204000691244253,0,0,0,0.125542639594803,0.305653622991805,0,0,0,0.383829398097213,0,0,0,0,0,0,0,0,0.200544447470142,0.217010870715852,0.447830948479849,0,0,0.290796477559129,0.377875943688809,0.485168122375632,0,0.411167888021826,0,0,0.256160706529101,0,0,0,0,0.376484679085209,0.545812300115692,0,0.306083892370903,0,0.639337125799041,0,0,0,0,0,0,0,0,0.434377689410233,0,0,0,0.211255286311942,0.212604299965044,0,0,0,0.32145117339416,0.285012743741249,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.205601498999509,0.167186495390678,0,0,0,0.334231370655521,0,0,0,0,0,0,0,0,0,0.535081656179426,0,0.113309342697566,0.383220493601921,0,0.253019692019503,0,0,0,0,0.127986611154418,0,0.236777252044017,0,0,0,0,0,0,0,0,0,0,0,0.486634870302636,0.189069634328136,0,0,0,0,0,0,0.174129737299267,0,0,0,0,0,0,0,0,0.419499436209906,0,0,0,0,0,0,0,0.24406205754817,0,0.81014194788176,0.17859945656816,0,0,0,0,0,0,0,0,0.496971951695318,0.12663051166458,0,0,0,0.560677600142307,0,0,0,0,0.163461903113459,0,0.576175924479999,0,0,0,0.149448680551801,0.117434498643765,0,0.140450806702248,0.204154171254893,0,0.413303124703062,1.18800285728205,0,0,0,0,0.250237039743928,0,0,0.612975591598039,0.45071417671979,0,0,0,0,0,0.103052529238439,0,0.18611685633159,0,0,0,0.0920498986422993,0,0,0.201504196455281,0.169560592310488,0,0,0,0.121973706129595,0.132529768321485,0.116193942869518,0.207322110030741,0,0,0,0,0,0.464367928031979,0,0,0,0.241011029883482,0,0.217879444092406,0,0,0,0,0,0,0,0,1.26755034821831,0,0,0,0.122988438543114,0,0,0,0,0.0925884451585296,0,0,0,0,0,0.144366447761074,0,0,0,0,0,0.234004265139238,0.148631162288728,0,0,0,0.0895585227028483,0.290633938513962,0,0,0.088048434013226,0,0,0.37872730027914,0.063497894292169,0,0,0,0.205654985406647,0,0.285826432630578,0.112131084345361,0,0,0.129271715757778,0,0,0,0,0,0,0.266422179016099,0.142977993658148,0,0,0,0,0,0,0,0.099972991182057,0,0,2.10833939483032,0,0,0,0,0.410952645100767,0.179060963239896,0,0,0.215627574859517,0.256686072559497,0,0,0,0.167516265334349,0,0.749007023947182,0,0,0.24538298343828,1.00034104211935,0,0.415941723061614,0.713715955188647,0.315404830067869,0.35142424497814,0.300946099727719,0,0,0,0,0.260650843404249,0,0.343143423810856,0,0.647142602455851,0.106727557803444,0,0,0,0.248107807818777,0,0,0.128139149255701,0,0.160853921143607,0,0.308419387605311,0,0,0,0.116210378459959,0,0,0.0920809889358963,0.114814448164607,0,0.393373244878272,0,0,0,0,0.105551628892876,1.13733384070897,0,0,0,0,0,0,0,0,0,0,0,0,0.325378394664303,0,0,0,0,0.650060246036521,0,0.096670718292122,0.154048617114644,0,0.275673144969061,0.107420244868274,0,0.426133137080504,0.178064071293475,0,0.384380134730212,0,0.4046311234222,0.464845549297286,0.31481234683064,0,0,0,0,0.18532421910392,0,0,0.316379424718726,0,0,0,0,0,0,0.54907405947211,0,0,0,0,0.48763373908959,0,0,0.136499911407986,0.282810863907425,0,0.551365343546124,0,0.438450885253763,0,0,0,0,0,0,0,0,0,0.633322905892992,0,0.379473173765715,0,0,0,0,0.188287601553558,0,0,0.886860307073351,0,0,0,0,0,0,0,0,0.79312517629427,0.213648142254946,0,0,0,0.144269212976445,0,0,0,0,0.846694330895531,0.649243880549111,0.280797178113459,0,0.156679895773023,0,0,0.1605880751037,0.201799707191048,0,0,0,0,0.166849141711909,0.390776190804081,0,0,0,0,0,0,0.293016358543788,0.242721043499027,0.111443384277478,0,0,0,0,0,0.703347082052564,0,0,0.211125408127993,0,0.552567831062295,0,0,0.123084805461069,0,0.0898683511473268,0,0.511572370226872,0.197286811273867,0,0,0.969332746095218,0.0927680981618513,0,0.260427761085233,0,0,0,0.254253650292766,0,0,0.291604613383254,0.347249989866585,0,0.120596438625408,1.52581736317083,0.663475559587348,0,0,0,0,0.0769502585037971,0.113942055847001,0.23056390438806,0.179515288819544,0.325942115766024,0.31900115973192,0.274792780205587,0,0,0,0.166211681900156,0.225595660617181,0,0.167821586975843,0,0,0.421996129056054,0,0,0,0,0,0,0,0,0.104421949505455,0,0.802577647298789,0.234264445725339,0.364909578431332,0,0,0,0,0.61214552326098,0.189559738885464,0,0.207376382794494,0,0.330991955875499,0,0,0,0,0.173559738335131,0.0979923974143777,0,0.698906672968121,0,0.19351266257817,0.584714536689484,0.164230914106418,0.193978032976839,0,0,0,0.19871461170299,0.0633107959558787,0,0.240476460754601,0.640358984218058,0,0,0.114536596165916,0.171594997861965,0,0.248505071130865,0,0,0,0,0.577901179803038,0,0.273810757783986,0,0,0,0,0.229160424011684,0,0.199679000498991,0,0,0.0671834724867263,0,0,0,0.247247575143499,0,0,0,0.795229689809303,0.408610218334727,0.160753148465019,0.137539436597234,0.83088067605837,0,0,0.121499113316049,0.335434687599266,0,0.0524545881349981,0,0,0.191915197319445,0,0.662091970365432,0,0,0,0.326587360109409,0,0,0,0.226624183040251,0,0,0,0.26446520348538,0,0,0,0.157204305099666,0,0.496166021811951,0,0.243585196761792,0,0,0,0,0.327872630709804,0.157054096250234,0,5.00307686098049,0.3755727921195,0,0,0.0620964029413835,0.415045904808692,0.124980407962107,0.151649117541648,0,0.235265819698172,0,0,0.149254802886874,0,0,0,0.251567901752575,0,0.228840068396924,0,0,0.147855149989634,0,0,0,0,0,0.521745061811734,0,0,0,0,0,0,0,0.400027764663154,0,0,0,0,0,0.260994291965212,0.453411851024545,0,0,0,0,0.219284049578707,0,0,0,0,0.345430341731199,0,0,0.194860308839388,0,0.163565394255844,0.655219697692825,0,0,0,0,0,0,0.368211900503681,0,0,0.127894371303652,0,0,0,0,0,0.371807292777007,0.558644917973244,0,0.315446980005013,0,0,0,0.192687675289379,0,0.478901577171454,0.205116364240755,0.504143392443436,0,0,0,0,0,0.366857197043358,0,0.381382095467167,0,0.397832444232549,0.225630985047772,0,0,0,0.327543835020193,0.147856086217045,0.270150338473579,0.781078098613847,0.413373593002368,0,0,0,0.496211178389294,0.527613733078862,0,0,0,0.606965604236632,0,0,0,0.171488009437418,0.0679697329768317,0.131545547125698,0.118193840883968,0,0,0.785577949580009,0,0,0.215927591218621,0,0.285906176706625,0.158013611732727,0,0,0,0.207216164163037,0.3414369541879,0,0,0.118332000730565,0.0852134047591577,1.27016115057279,0,0,0,0,0.098150233615243,0.121917924982269,0,0,0,0,0,0.397901550322736,0.118920090777569,0,0.109940516745429,0,0,0,0,0.245148321753905,0,0.981542335574726,0,0.4226557275834,0,0,0,0,0.178553938605658,0,0.160482733378337,0.730336388246517,0.458729283404541,0.143339583151451,0.157771562193185,0.203974470572744,1.30905207102113,0,0.743990036333503,0.462175628631418,0,0.252332849670158,0.109265571963696,0.506794004045748,0,0,0.0918948995348449,0.250707539292375,0.0757786982182394,0,0,0.103432995861895,0.639701945702943,0.714193294391221,0.322944549180031,0,0,0,0,0.217716747896961,0,0,0,0,0.0814032686109745,0,0,0.0898252021065869,0,0.366724332548599,0.406896178315738,0,0,0 | |||
|short_description=p6@MAP2K5 | |||
}} |
Revision as of 07:58, 11 September 2013
Short description: | p6@MAP2K5 |
---|---|
Species: | Human (Homo sapiens) |
DPI dataset: | NA |
TSS-like-by-RIKEN-classifier(Yes/No): | NA |
DHS support(Yes/No): | NA |
Description: | CAGE_peak_6_at_MAP2K5_5end |
Coexpression cluster: | NA |
Association with transcript: | 169bp_to_ENST00000178640_5end |
EntrezGene: | MAP2K5 |
HGNC: | 6845 |
UniProt: | Q13163 |
Genome view: | ZENBU |
View on UCSC genome browser
CAGE Expression
- Click each plot point to find sample in table
Ontology-based sample term enrichment analysis<b>Summary:</b>This analysis has been performed by utilizing wilcoxon rank sum test.When the number of associated cells/tissues are > n , randomly sampled n cells/tissues are used for P value calculation with rank sum test. this process are repeated several times, and the P values are averaged on the log space <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source dataset<br>data
Ontology term | p-value | n |
---|---|---|
nucleus pulposus cell of intervertebral disc | 8.29e-08 | 3 |
Ontology term | p-value | n |
---|---|---|
seminal vesicle | 4.22e-21 | 1 |
seminal fluid secreting gland | 4.22e-21 | 1 |
middle temporal gyrus | 1.82e-11 | 2 |
mesonephros | 1.01e-09 | 9 |
pronephros | 1.01e-09 | 9 |
nephrogenic cord | 1.01e-09 | 9 |
pronephric mesoderm | 1.01e-09 | 9 |
rostral part of nephrogenic cord | 1.01e-09 | 9 |
presumptive pronephric mesoderm | 1.01e-09 | 9 |
urogenital ridge | 4.04e-08 | 11 |
duodenum | 5.93e-08 | 2 |
male genital duct | 6.34e-08 | 3 |
internal male genitalia | 6.34e-08 | 3 |
nucleus pulposus | 8.29e-08 | 3 |
axial mesoderm | 8.29e-08 | 3 |
notochord | 8.29e-08 | 3 |
chordamesoderm | 8.29e-08 | 3 |
intraembryonic coelom | 1.62e-07 | 12 |
Property "DHS support" (as page type) with input value "{{{DHSsupport}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.