Novel motif:116

name:	motif116_CCAARA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0048739	cardiac muscle fiber development	4.726030e-32
GO:0030241	skeletal muscle myosin thick filament assembly	2.342931e-25
GO:0030049	muscle filament sliding	1.858757e-23
GO:0070252	actin-mediated cell contraction	1.410107e-22
GO:0030048	actin filament-based movement	2.502953e-22
GO:0006941	striated muscle contraction	6.395242e-22
GO:0048738	cardiac muscle tissue development	2.157012e-20
GO:0014866	skeletal myofibril assembly	5.694535e-20
GO:0009611	response to wounding	6.317441e-19
GO:0006936	muscle contraction	1.551633e-18
GO:0006928	cellular component movement	1.732680e-18
GO:0051179	localization	5.863073e-17
GO:0010951	negative regulation of endopeptidase activity	6.008940e-17
GO:0006954	inflammatory response	8.356319e-17
GO:0030239	myofibril assembly	1.026234e-16
GO:0055013	cardiac muscle cell development	2.571776e-16
GO:0051234	establishment of localization	2.687832e-16
GO:0048769	sarcomerogenesis	3.301022e-16
GO:0030261	chromosome condensation	7.700767e-16
GO:0003012	muscle system process	8.163395e-16
GO:0006810	transport	1.983512e-15
GO:0010927	cellular component assembly involved in morphogenesis	2.052364e-15
GO:0048644	muscle organ morphogenesis	3.956752e-15
GO:0046890	regulation of lipid biosynthetic process	4.445083e-15
GO:0060415	muscle tissue morphogenesis	7.225723e-15
GO:0031032	actomyosin structure organization	8.861612e-15
GO:0006950	response to stress	1.474726e-14
GO:0045214	sarcomere organization	2.796368e-14
GO:0030029	actin filament-based process	3.008863e-14
GO:0055008	cardiac muscle tissue morphogenesis	5.385385e-14
GO:0006952	defense response	1.220494e-13
GO:0002576	platelet degranulation	1.895881e-13
GO:0051146	striated muscle cell differentiation	2.548678e-13
GO:0042221	response to chemical stimulus	2.558040e-13
GO:0048251	elastic fiber assembly	4.405357e-13
GO:0019216	regulation of lipid metabolic process	6.313328e-13
GO:0051298	centrosome duplication	9.599251e-13
GO:0046903	secretion	1.218738e-12
GO:0006887	exocytosis	1.424586e-12
GO:0007076	mitotic chromosome condensation	2.647351e-12
GO:0050896	response to stimulus	4.693756e-12
GO:0034097	response to cytokine stimulus	5.223300e-12
GO:0048747	muscle fiber development	7.100378e-12
GO:0055001	muscle cell development	7.122606e-12
GO:0002376	immune system process	7.307108e-12
GO:0001775	cell activation	7.507511e-12
GO:0030240	skeletal muscle thin filament assembly	9.361800e-12
GO:0085029	extracellular matrix assembly	1.015052e-11
GO:0055007	cardiac muscle cell differentiation	1.030610e-11
GO:0055003	cardiac myofibril assembly	1.082232e-11
GO:0016192	vesicle-mediated transport	1.119293e-11
GO:0000070	mitotic sister chromatid segregation	1.432521e-11
GO:0010035	response to inorganic substance	1.991827e-11
GO:0009888	tissue development	2.433235e-11
GO:0032940	secretion by cell	2.530011e-11
GO:0010033	response to organic substance	3.045966e-11
GO:0000819	sister chromatid segregation	4.641159e-11
GO:0000279	M phase	5.115089e-11
GO:0050900	leukocyte migration	5.919756e-11
GO:0030010	establishment of cell polarity	8.449493e-11
GO:0051293	establishment of spindle localization	8.715682e-11
GO:0030036	actin cytoskeleton organization	9.194664e-11
GO:0051649	establishment of localization in cell	1.021926e-10
GO:0009725	response to hormone stimulus	1.149797e-10
GO:0046885	regulation of hormone biosynthetic process	1.593076e-10
GO:0055002	striated muscle cell development	1.629682e-10
GO:0060537	muscle tissue development	1.689037e-10
GO:0051641	cellular localization	1.708392e-10
GO:0006953	acute-phase response	2.190137e-10
GO:0003007	heart morphogenesis	2.601263e-10
GO:0046709	IDP catabolic process	2.660254e-10
GO:0046032	ADP catabolic process	2.660254e-10
GO:0000087	M phase of mitotic cell cycle	3.924790e-10
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	4.857318e-10
GO:0006633	fatty acid biosynthetic process	4.901452e-10
GO:0007067	mitosis	4.916658e-10
GO:0003008	system process	5.824020e-10
GO:0032501	multicellular organismal process	6.792808e-10
GO:0006955	immune response	6.897935e-10
GO:0030100	regulation of endocytosis	7.075414e-10
GO:0006323	DNA packaging	7.096983e-10
GO:0030168	platelet activation	7.803559e-10
GO:0048513	organ development	8.694405e-10
GO:0010038	response to metal ion	9.898458e-10
GO:0048285	organelle fission	1.095725e-9
GO:0065008	regulation of biological quality	1.345116e-9
GO:0032637	interleukin-8 production	1.357720e-9
GO:0042060	wound healing	1.463627e-9
GO:0007098	centrosome cycle	1.494778e-9
GO:0044240	multicellular organismal lipid catabolic process	1.559561e-9
GO:0071103	DNA conformation change	2.028964e-9
GO:0014706	striated muscle tissue development	2.231728e-9
GO:0008645	hexose transport	2.974174e-9
GO:0009617	response to bacterium	3.170629e-9
GO:0015749	monosaccharide transport	4.108268e-9
GO:0034612	response to tumor necrosis factor	4.575644e-9
GO:0007507	heart development	4.672086e-9
GO:0010466	negative regulation of peptidase activity	4.905977e-9
GO:0040017	positive regulation of locomotion	5.079596e-9
GO:0090030	regulation of steroid hormone biosynthetic process	5.240095e-9
GO:0015758	glucose transport	5.389062e-9
GO:0030335	positive regulation of cell migration	6.070369e-9
GO:0046889	positive regulation of lipid biosynthetic process	6.146841e-9
GO:0051346	negative regulation of hydrolase activity	6.425751e-9
GO:0019218	regulation of steroid metabolic process	6.827642e-9
GO:0032879	regulation of localization	6.920274e-9
GO:0071345	cellular response to cytokine stimulus	7.242163e-9
GO:0050974	detection of mechanical stimulus involved in sensory perception	7.698746e-9
GO:0002028	regulation of sodium ion transport	9.027151e-9
GO:0071356	cellular response to tumor necrosis factor	9.619275e-9
GO:0043627	response to estrogen stimulus	1.042724e-8
GO:0007522	visceral muscle development	1.391728e-8
GO:0042446	hormone biosynthetic process	1.431568e-8
GO:2000147	positive regulation of cell motility	1.652492e-8
GO:0051272	positive regulation of cellular component movement	1.792030e-8
GO:0006869	lipid transport	1.877875e-8
GO:0016075	rRNA catabolic process	1.970640e-8
GO:0002526	acute inflammatory response	2.249791e-8
GO:0010876	lipid localization	2.288916e-8
GO:0031099	regeneration	2.318950e-8
GO:0009719	response to endogenous stimulus	2.749337e-8
GO:0006766	vitamin metabolic process	3.227701e-8
GO:0048520	positive regulation of behavior	3.499918e-8
GO:0010288	response to lead ion	3.547819e-8
GO:0022414	reproductive process	3.677415e-8
GO:0052548	regulation of endopeptidase activity	3.930243e-8
GO:0042692	muscle cell differentiation	4.100778e-8
GO:0006082	organic acid metabolic process	4.203794e-8
GO:0000003	reproduction	4.401287e-8
GO:0043434	response to peptide hormone stimulus	4.591373e-8
GO:0051704	multi-organism process	4.654264e-8
GO:0032103	positive regulation of response to external stimulus	5.055359e-8
GO:0010766	negative regulation of sodium ion transport	5.556665e-8
GO:0046886	positive regulation of hormone biosynthetic process	5.806693e-8
GO:0007010	cytoskeleton organization	5.998136e-8
GO:0051049	regulation of transport	6.314660e-8
GO:0007015	actin filament organization	6.379346e-8
GO:0050810	regulation of steroid biosynthetic process	7.097608e-8
GO:0072358	cardiovascular system development	7.549253e-8
GO:0050927	positive regulation of positive chemotaxis	7.695970e-8
GO:0046456	icosanoid biosynthetic process	9.637086e-8
GO:0007599	hemostasis	9.889395e-8
GO:0050921	positive regulation of chemotaxis	1.057401e-7
GO:0008228	opsonization	1.120319e-7
GO:0048646	anatomical structure formation involved in morphogenesis	1.135266e-7
GO:0060627	regulation of vesicle-mediated transport	1.312237e-7
GO:0032269	negative regulation of cellular protein metabolic process	1.414561e-7
GO:0050926	regulation of positive chemotaxis	1.469743e-7
GO:0007596	blood coagulation	1.515209e-7
GO:0051707	response to other organism	1.939545e-7
GO:0007163	establishment or maintenance of cell polarity	1.946114e-7
GO:0042180	cellular ketone metabolic process	2.083572e-7
GO:0072376	protein activation cascade	2.099802e-7
GO:0071702	organic substance transport	2.100056e-7
GO:0006636	unsaturated fatty acid biosynthetic process	2.115447e-7
GO:0052547	regulation of peptidase activity	2.231929e-7
GO:0048608	reproductive structure development	2.659001e-7
GO:0019752	carboxylic acid metabolic process	2.958367e-7
GO:0030593	neutrophil chemotaxis	3.024047e-7
GO:0044243	multicellular organismal catabolic process	3.065357e-7
GO:0050906	detection of stimulus involved in sensory perception	3.104813e-7
GO:0006959	humoral immune response	3.146305e-7
GO:0045807	positive regulation of endocytosis	3.157335e-7
GO:0045766	positive regulation of angiogenesis	3.327797e-7
GO:0040012	regulation of locomotion	3.472137e-7
GO:0009181	purine ribonucleoside diphosphate catabolic process	3.556118e-7
GO:0045940	positive regulation of steroid metabolic process	3.669100e-7
GO:0051248	negative regulation of protein metabolic process	3.696939e-7
GO:0006631	fatty acid metabolic process	4.070004e-7
GO:0001819	positive regulation of cytokine production	4.126679e-7
GO:0050878	regulation of body fluid levels	4.607159e-7
GO:0000132	establishment of mitotic spindle orientation	4.741209e-7
GO:0010574	regulation of vascular endothelial growth factor production	4.935731e-7
GO:0003230	cardiac atrium development	5.043739e-7
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.628621e-7
GO:0035051	cardiac cell differentiation	5.651016e-7
GO:0048870	cell motility	6.308218e-7
GO:0040001	establishment of mitotic spindle localization	6.802678e-7
GO:0034694	response to prostaglandin stimulus	7.219215e-7
GO:0061162	establishment of monopolar cell polarity	7.309939e-7
GO:0042493	response to drug	8.092025e-7
GO:0003026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	8.587534e-7
GO:0001300	chronological cell aging	9.014253e-7
GO:0032101	regulation of response to external stimulus	9.075782e-7
GO:0050982	detection of mechanical stimulus	9.301662e-7
GO:0019724	B cell mediated immunity	9.304087e-7
GO:0032355	response to estradiol stimulus	9.330482e-7
GO:0003006	developmental process involved in reproduction	9.732737e-7
GO:0044236	multicellular organismal metabolic process	9.805532e-7
GO:0070555	response to interleukin-1	1.110101e-6
GO:0044085	cellular component biogenesis	1.188088e-6
GO:0042304	regulation of fatty acid biosynthetic process	1.193406e-6
GO:0051297	centrosome organization	1.198873e-6
GO:0048545	response to steroid hormone stimulus	1.271722e-6
GO:0006434	seryl-tRNA aminoacylation	1.322871e-6
GO:0001938	positive regulation of endothelial cell proliferation	1.344315e-6
GO:0016477	cell migration	1.345241e-6
GO:0001933	negative regulation of protein phosphorylation	1.367428e-6
GO:0043269	regulation of ion transport	1.431798e-6
GO:0048584	positive regulation of response to stimulus	1.436850e-6
GO:0090031	positive regulation of steroid hormone biosynthetic process	1.451015e-6
GO:2000145	regulation of cell motility	1.456862e-6
GO:0007584	response to nutrient	1.479433e-6
GO:0044281	small molecule metabolic process	1.505428e-6
GO:0031100	organ regeneration	1.525444e-6
GO:0032350	regulation of hormone metabolic process	1.528174e-6
GO:0042592	homeostatic process	1.534686e-6
GO:0032352	positive regulation of hormone metabolic process	1.567895e-6
GO:0002237	response to molecule of bacterial origin	1.592345e-6
GO:0046394	carboxylic acid biosynthetic process	1.634184e-6
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.810205e-6
GO:0009628	response to abiotic stimulus	1.810982e-6
GO:0009607	response to biotic stimulus	1.812281e-6
GO:0035089	establishment of apical/basal cell polarity	1.885397e-6
GO:0031400	negative regulation of protein modification process	1.907150e-6
GO:0002682	regulation of immune system process	1.985740e-6
GO:0051270	regulation of cellular component movement	2.015663e-6
GO:0010893	positive regulation of steroid biosynthetic process	2.018368e-6
GO:0014912	negative regulation of smooth muscle cell migration	2.034663e-6
GO:0019217	regulation of fatty acid metabolic process	2.051044e-6
GO:0022409	positive regulation of cell-cell adhesion	2.075796e-6
GO:0051131	chaperone-mediated protein complex assembly	2.083291e-6
GO:0007598	blood coagulation, extrinsic pathway	2.122377e-6
GO:0071529	cementum mineralization	2.290878e-6
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	2.382076e-6
GO:0061061	muscle structure development	2.391491e-6
GO:0007569	cell aging	2.487270e-6
GO:0014067	negative regulation of phosphatidylinositol 3-kinase cascade	2.540769e-6
GO:0071353	cellular response to interleukin-4	2.675812e-6
GO:0022408	negative regulation of cell-cell adhesion	2.725593e-6
GO:0032530	regulation of microvillus organization	2.741678e-6
GO:0046677	response to antibiotic	2.790883e-6
GO:0018894	dibenzo-p-dioxin metabolic process	2.879318e-6
GO:0007059	chromosome segregation	3.105629e-6
GO:0031947	negative regulation of glucocorticoid biosynthetic process	3.179095e-6
GO:0051239	regulation of multicellular organismal process	3.221028e-6
GO:0045066	regulatory T cell differentiation	3.246329e-6
GO:0009566	fertilization	3.369314e-6
GO:0030334	regulation of cell migration	3.397422e-6
GO:0016598	protein arginylation	3.499919e-6
GO:0006883	cellular sodium ion homeostasis	3.723097e-6
GO:0001738	morphogenesis of a polarized epithelium	3.842907e-6
GO:0006066	alcohol metabolic process	4.287965e-6
GO:0032787	monocarboxylic acid metabolic process	4.351686e-6
GO:0016125	sterol metabolic process	4.386165e-6
GO:0006725	cellular aromatic compound metabolic process	4.475272e-6
GO:0022600	digestive system process	4.532027e-6
GO:0002688	regulation of leukocyte chemotaxis	4.542754e-6
GO:0080134	regulation of response to stress	4.684464e-6
GO:0044106	cellular amine metabolic process	4.881420e-6
GO:0045321	leukocyte activation	4.898410e-6
GO:0071320	cellular response to cAMP	5.044579e-6
GO:0051930	regulation of sensory perception of pain	5.109824e-6
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	5.263392e-6
GO:0060137	maternal process involved in parturition	5.286034e-6
GO:0032431	activation of phospholipase A2 activity	5.836550e-6
GO:0071347	cellular response to interleukin-1	6.286215e-6
GO:0051303	establishment of chromosome localization	6.390409e-6
GO:0070887	cellular response to chemical stimulus	6.767692e-6
GO:0034446	substrate adhesion-dependent cell spreading	6.806651e-6
GO:0019953	sexual reproduction	6.931364e-6
GO:0032496	response to lipopolysaccharide	7.044512e-6
GO:0019538	protein metabolic process	7.167898e-6
GO:2000098	negative regulation of smooth muscle cell-matrix adhesion	7.616036e-6
GO:0071258	cellular response to gravity	7.616036e-6
GO:0035491	positive regulation of leukotriene production involved in inflammatory response	7.616036e-6
GO:0061044	negative regulation of vascular wound healing	7.616036e-6
GO:0048729	tissue morphogenesis	7.884114e-6
GO:0032353	negative regulation of hormone biosynthetic process	7.972770e-6
GO:0006414	translational elongation	8.294311e-6
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	8.301483e-6
GO:0061010	gall bladder development	8.343654e-6
GO:0048610	cellular process involved in reproduction	8.589088e-6
GO:0048002	antigen processing and presentation of peptide antigen	8.630759e-6
GO:0009308	amine metabolic process	8.657878e-6
GO:0046717	acid secretion	8.670153e-6
GO:0045123	cellular extravasation	8.747565e-6
GO:0001817	regulation of cytokine production	9.036529e-6
GO:0031667	response to nutrient levels	9.261716e-6
GO:0060676	ureteric bud formation	9.285959e-6
GO:0035684	helper T cell extravasation	9.501758e-6
GO:0010827	regulation of glucose transport	9.548065e-6
GO:0051295	establishment of meiotic spindle localization	9.677636e-6
GO:0050920	regulation of chemotaxis	9.926406e-6
GO:0003209	cardiac atrium morphogenesis	1.015666e-5
GO:0050776	regulation of immune response	1.088499e-5
GO:0010575	positive regulation vascular endothelial growth factor production	1.132561e-5
GO:0015760	glucose-6-phosphate transport	1.177895e-5
GO:0045834	positive regulation of lipid metabolic process	1.197320e-5
GO:0032425	positive regulation of mismatch repair	1.236416e-5
GO:0002684	positive regulation of immune system process	1.241114e-5
GO:0008284	positive regulation of cell proliferation	1.286447e-5
GO:0006956	complement activation	1.333108e-5
GO:0031023	microtubule organizing center organization	1.378024e-5
GO:0006629	lipid metabolic process	1.383342e-5
GO:0019725	cellular homeostasis	1.406718e-5
GO:0048146	positive regulation of fibroblast proliferation	1.465530e-5
GO:0030277	maintenance of gastrointestinal epithelium	1.501079e-5
GO:0051241	negative regulation of multicellular organismal process	1.523404e-5
GO:0015705	iodide transport	1.576607e-5
GO:0008202	steroid metabolic process	1.593993e-5
GO:0051130	positive regulation of cellular component organization	1.728894e-5
GO:0002685	regulation of leukocyte migration	1.734391e-5
GO:0033630	positive regulation of cell adhesion mediated by integrin	1.741789e-5
GO:2000679	positive regulation of transcription regulatory region DNA binding	1.876346e-5
GO:0007132	meiotic metaphase I	1.912751e-5
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	1.920640e-5
GO:0033566	gamma-tubulin complex localization	1.938114e-5
GO:0002250	adaptive immune response	1.940258e-5
GO:0051186	cofactor metabolic process	1.940548e-5
GO:0006907	pinocytosis	1.949325e-5
GO:0003009	skeletal muscle contraction	1.977581e-5
GO:0009156	ribonucleoside monophosphate biosynthetic process	1.987097e-5
GO:0050801	ion homeostasis	2.015417e-5
GO:0044255	cellular lipid metabolic process	2.064881e-5
GO:0002274	myeloid leukocyte activation	2.118977e-5
GO:0006732	coenzyme metabolic process	2.132495e-5
GO:0034661	ncRNA catabolic process	2.206806e-5
GO:0048247	lymphocyte chemotaxis	2.207439e-5
GO:0015980	energy derivation by oxidation of organic compounds	2.290471e-5
GO:0050714	positive regulation of protein secretion	2.295291e-5
GO:0007155	cell adhesion	2.396478e-5
GO:0051054	positive regulation of DNA metabolic process	2.405375e-5
GO:0009437	carnitine metabolic process	2.442452e-5
GO:0022407	regulation of cell-cell adhesion	2.519562e-5
GO:0001554	luteolysis	2.596597e-5
GO:0042758	long-chain fatty acid catabolic process	2.618905e-5
GO:0042413	carnitine catabolic process	2.618905e-5
GO:0006775	fat-soluble vitamin metabolic process	2.649227e-5
GO:0050708	regulation of protein secretion	2.746562e-5
GO:0044057	regulation of system process	2.877469e-5
GO:0030859	polarized epithelial cell differentiation	2.947402e-5
GO:0042177	negative regulation of protein catabolic process	2.960630e-5
GO:0055078	sodium ion homeostasis	3.006257e-5
GO:0061011	hepatic duct development	3.008953e-5
GO:0044283	small molecule biosynthetic process	3.051870e-5
GO:0019370	leukotriene biosynthetic process	3.069691e-5
GO:0010623	developmental programmed cell death	3.223871e-5
GO:0050806	positive regulation of synaptic transmission	3.255428e-5
GO:0035058	nonmotile primary cilium assembly	3.267222e-5
GO:0009191	ribonucleoside diphosphate catabolic process	3.451479e-5
GO:0022402	cell cycle process	3.453576e-5
GO:0010595	positive regulation of endothelial cell migration	3.489491e-5
GO:0035881	amacrine cell differentiation	3.549962e-5
GO:0016064	immunoglobulin mediated immune response	3.567206e-5
GO:0009895	negative regulation of catabolic process	3.750217e-5
GO:0033993	response to lipid	3.792981e-5
GO:0051240	positive regulation of multicellular organismal process	3.894426e-5
GO:0010621	negative regulation of transcription by transcription factor localization	3.894716e-5
GO:0048609	multicellular organismal reproductive process	4.081238e-5
GO:0048878	chemical homeostasis	4.095621e-5
GO:0051591	response to cAMP	4.108424e-5
GO:0048742	regulation of skeletal muscle fiber development	4.458017e-5
GO:0070145	mitochondrial asparaginyl-tRNA aminoacylation	4.467680e-5
GO:0007166	cell surface receptor linked signaling pathway	4.515406e-5
GO:0006996	organelle organization	4.539697e-5
GO:0010565	regulation of cellular ketone metabolic process	4.669351e-5
GO:0021543	pallium development	4.715236e-5
GO:0034696	response to prostaglandin F stimulus	4.847882e-5
GO:0070543	response to linoleic acid	4.847882e-5
GO:0035105	sterol regulatory element binding protein import into nucleus	4.874828e-5
GO:0060070	canonical Wnt receptor signaling pathway	4.920993e-5
GO:0048583	regulation of response to stimulus	4.968180e-5
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	4.986496e-5
GO:0031960	response to corticosteroid stimulus	5.212494e-5
GO:0035883	enteroendocrine cell differentiation	5.266240e-5
GO:0032429	regulation of phospholipase A2 activity	5.362897e-5
GO:0007320	insemination	5.415758e-5
GO:0050793	regulation of developmental process	5.479492e-5
GO:0048627	myoblast development	5.485245e-5
GO:0015920	lipopolysaccharide transport	5.485245e-5
GO:0051384	response to glucocorticoid stimulus	5.486483e-5
GO:0008203	cholesterol metabolic process	5.590101e-5
GO:0048589	developmental growth	5.680486e-5
GO:0016310	phosphorylation	5.700892e-5
GO:0006958	complement activation, classical pathway	5.729117e-5
GO:0006091	generation of precursor metabolites and energy	5.767236e-5
GO:0032534	regulation of microvillus assembly	5.774713e-5
GO:0030317	sperm motility	5.803242e-5
GO:0007608	sensory perception of smell	6.153929e-5
GO:0042254	ribosome biogenesis	6.157078e-5
GO:0034111	negative regulation of homotypic cell-cell adhesion	6.299461e-5
GO:0046426	negative regulation of JAK-STAT cascade	6.352919e-5
GO:0015698	inorganic anion transport	6.487011e-5
GO:0009161	ribonucleoside monophosphate metabolic process	6.564702e-5
GO:0090068	positive regulation of cell cycle process	6.886660e-5
GO:0071158	positive regulation of cell cycle arrest	6.979427e-5
GO:0018904	organic ether metabolic process	7.019572e-5
GO:0014061	regulation of norepinephrine secretion	7.028518e-5
GO:0044241	lipid digestion	7.085070e-5
GO:0007162	negative regulation of cell adhesion	7.159469e-5
GO:0032673	regulation of interleukin-4 production	7.162090e-5
GO:0033036	macromolecule localization	7.380074e-5
GO:0016337	cell-cell adhesion	7.483135e-5
GO:0046031	ADP metabolic process	7.770009e-5
GO:0032963	collagen metabolic process	7.787906e-5
GO:0006144	purine base metabolic process	7.787906e-5
GO:0007606	sensory perception of chemical stimulus	7.835026e-5
GO:0016072	rRNA metabolic process	7.852404e-5
GO:0002690	positive regulation of leukocyte chemotaxis	7.857545e-5
GO:0071379	cellular response to prostaglandin stimulus	7.929590e-5
GO:0060157	urinary bladder development	8.017328e-5
GO:0048856	anatomical structure development	8.047243e-5
GO:0044259	multicellular organismal macromolecule metabolic process	8.331500e-5
GO:0051725	protein de-ADP-ribosylation	8.387580e-5
GO:0051409	response to nitrosative stress	8.398305e-5
GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback	8.454044e-5
GO:0045833	negative regulation of lipid metabolic process	8.548716e-5
GO:0050866	negative regulation of cell activation	8.687131e-5
GO:0002455	humoral immune response mediated by circulating immunoglobulin	8.701992e-5
GO:0009448	gamma-aminobutyric acid metabolic process	8.752222e-5
GO:0006820	anion transport	8.910488e-5
GO:0006109	regulation of carbohydrate metabolic process	8.911166e-5
GO:0032502	developmental process	9.200270e-5
GO:0050795	regulation of behavior	9.293408e-5
GO:0050865	regulation of cell activation	9.406338e-5
GO:0006700	C21-steroid hormone biosynthetic process	9.433068e-5
GO:0019882	antigen processing and presentation	9.537799e-5
GO:0051454	intracellular pH elevation	9.605597e-5
GO:0060571	morphogenesis of an epithelial fold	9.649592e-5
GO:0032430	positive regulation of phospholipase A2 activity	9.667791e-5
GO:0048585	negative regulation of response to stimulus	9.753968e-5
GO:0006690	icosanoid metabolic process	9.782811e-5
GO:0060730	regulation of intestinal epithelial structure maintenance	9.788440e-5
GO:0051128	regulation of cellular component organization	9.860353e-5
GO:0007586	digestion	1.025496e-4
GO:0009060	aerobic respiration	1.057260e-4
GO:0060992	response to fungicide	1.069661e-4
GO:0050482	arachidonic acid secretion	1.086765e-4
GO:0043623	cellular protein complex assembly	1.098939e-4
GO:0071715	icosanoid transport	1.127092e-4
GO:0002687	positive regulation of leukocyte migration	1.144221e-4
GO:0030186	melatonin metabolic process	1.162602e-4
GO:0030195	negative regulation of blood coagulation	1.164682e-4
GO:0022607	cellular component assembly	1.184716e-4
GO:0006508	proteolysis	1.186394e-4
GO:0007568	aging	1.205186e-4
GO:0055114	oxidation-reduction process	1.216672e-4
GO:0071840	cellular component organization or biogenesis	1.245631e-4
GO:0046320	regulation of fatty acid oxidation	1.246732e-4
GO:0018879	biphenyl metabolic process	1.330579e-4
GO:0018963	phthalate metabolic process	1.387415e-4
GO:0071214	cellular response to abiotic stimulus	1.398993e-4
GO:0051790	short-chain fatty acid biosynthetic process	1.417246e-4
GO:0033559	unsaturated fatty acid metabolic process	1.453700e-4
GO:0006873	cellular ion homeostasis	1.479930e-4
GO:2000097	regulation of smooth muscle cell-matrix adhesion	1.480196e-4
GO:0034014	response to triglyceride	1.504441e-4
GO:0010669	epithelial structure maintenance	1.525639e-4
GO:0006691	leukotriene metabolic process	1.531275e-4
GO:0010701	positive regulation of norepinephrine secretion	1.565918e-4
GO:0006767	water-soluble vitamin metabolic process	1.594719e-4
GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	1.594931e-4
GO:0043069	negative regulation of programmed cell death	1.599669e-4
GO:0002720	positive regulation of cytokine production involved in immune response	1.610155e-4
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	1.629243e-4
GO:0009605	response to external stimulus	1.632239e-4
GO:0043066	negative regulation of apoptosis	1.668298e-4
GO:0006721	terpenoid metabolic process	1.670589e-4
GO:0007049	cell cycle	1.694081e-4
GO:0009991	response to extracellular stimulus	1.720006e-4
GO:0043129	surfactant homeostasis	1.814217e-4
GO:0050819	negative regulation of coagulation	1.844479e-4
GO:0010675	regulation of cellular carbohydrate metabolic process	1.851509e-4
GO:0009260	ribonucleotide biosynthetic process	1.852974e-4
GO:0051597	response to methylmercury	1.865176e-4
GO:0030850	prostate gland development	1.874815e-4
GO:0061077	chaperone-mediated protein folding	1.901655e-4
GO:0021987	cerebral cortex development	1.913973e-4
GO:0044403	symbiosis, encompassing mutualism through parasitism	1.930307e-4
GO:0007154	cell communication	1.952508e-4
GO:0045663	positive regulation of myoblast differentiation	1.962558e-4
GO:0002718	regulation of cytokine production involved in immune response	1.989300e-4
GO:0071310	cellular response to organic substance	2.021403e-4
GO:0055082	cellular chemical homeostasis	2.035930e-4
GO:0023056	positive regulation of signaling	2.051294e-4
GO:0006897	endocytosis	2.126271e-4
GO:0090181	regulation of cholesterol metabolic process	2.184707e-4
GO:0008610	lipid biosynthetic process	2.228420e-4
GO:0042246	tissue regeneration	2.270863e-4
GO:0010647	positive regulation of cell communication	2.309268e-4
GO:0009449	gamma-aminobutyric acid biosynthetic process	2.315927e-4
GO:0060548	negative regulation of cell death	2.336723e-4
GO:0007512	adult heart development	2.341060e-4
GO:2000677	regulation of transcription regulatory region DNA binding	2.352719e-4
GO:0008643	carbohydrate transport	2.372012e-4
GO:0010646	regulation of cell communication	2.379256e-4
GO:0009887	organ morphogenesis	2.435888e-4
GO:0023052	signaling	2.438470e-4
GO:0010959	regulation of metal ion transport	2.503799e-4
GO:0001934	positive regulation of protein phosphorylation	2.517504e-4
GO:0042742	defense response to bacterium	2.524880e-4
GO:0009268	response to pH	2.551218e-4
GO:0009069	serine family amino acid metabolic process	2.627064e-4
GO:0009071	serine family amino acid catabolic process	2.627841e-4
GO:0021509	roof plate formation	2.633357e-4
GO:0000212	meiotic spindle organization	2.635404e-4
GO:0060461	right lung morphogenesis	2.647389e-4
GO:0060446	branching involved in open tracheal system development	2.647389e-4
GO:0090131	mesenchyme migration	2.647389e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0044259	multicellular organismal macromolecule metabolic process	4.900695e-13
GO:0032963	collagen metabolic process	6.421865e-13
GO:0045653	negative regulation of megakaryocyte differentiation	3.820412e-12
GO:0044236	multicellular organismal metabolic process	1.292873e-11
GO:0070208	protein heterotrimerization	2.074213e-11
GO:0050953	sensory perception of light stimulus	1.548633e-10
GO:0007601	visual perception	1.744704e-10
GO:0031667	response to nutrient levels	2.547847e-10
GO:0009991	response to extracellular stimulus	6.233621e-10
GO:0007600	sensory perception	7.762988e-10
GO:0010269	response to selenium ion	1.359881e-8
GO:0007584	response to nutrient	1.411755e-8
GO:0003008	system process	2.070954e-8
GO:0000072	M phase specific microtubule process	2.231289e-8
GO:0030574	collagen catabolic process	2.270191e-8
GO:0070206	protein trimerization	2.816154e-8
GO:0006936	muscle contraction	3.233159e-8
GO:0009607	response to biotic stimulus	3.238890e-8
GO:0019221	cytokine-mediated signaling pathway	4.554606e-8
GO:0000302	response to reactive oxygen species	1.583828e-7
GO:0032792	negative regulation of CREB transcription factor activity	2.013188e-7
GO:0031960	response to corticosteroid stimulus	2.128246e-7
GO:0045085	negative regulation of interleukin-2 biosynthetic process	2.617630e-7
GO:0030573	bile acid catabolic process	2.713836e-7
GO:0002252	immune effector process	3.344054e-7
GO:0071345	cellular response to cytokine stimulus	3.495984e-7
GO:0007021	tubulin complex assembly	4.131591e-7
GO:0090074	negative regulation of protein homodimerization activity	4.211782e-7
GO:0009303	rRNA transcription	5.118498e-7
GO:0071396	cellular response to lipid	5.330094e-7
GO:0060828	regulation of canonical Wnt receptor signaling pathway	5.779575e-7
GO:0034374	low-density lipoprotein particle remodeling	8.978616e-7
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.024001e-6
GO:0060561	apoptosis involved in morphogenesis	1.061905e-6
GO:0010035	response to inorganic substance	1.118294e-6
GO:0071300	cellular response to retinoic acid	1.268932e-6
GO:0003012	muscle system process	1.367977e-6
GO:0071299	cellular response to vitamin A	1.558463e-6
GO:0044242	cellular lipid catabolic process	1.654387e-6
GO:0051707	response to other organism	1.684570e-6
GO:0045540	regulation of cholesterol biosynthetic process	1.971976e-6
GO:0035094	response to nicotine	2.079770e-6
GO:0050877	neurological system process	2.196279e-6
GO:0071379	cellular response to prostaglandin stimulus	2.279825e-6
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	2.828429e-6
GO:0032966	negative regulation of collagen biosynthetic process	4.201388e-6
GO:0045721	negative regulation of gluconeogenesis	4.213707e-6
GO:0032964	collagen biosynthetic process	4.553031e-6
GO:0009743	response to carbohydrate stimulus	4.739628e-6
GO:0032501	multicellular organismal process	4.777482e-6
GO:0030199	collagen fibril organization	4.934243e-6
GO:0072333	signal transduction by p53 class mediator resulting in induction of anoikis	5.127757e-6
GO:0044243	multicellular organismal catabolic process	5.244794e-6
GO:0055002	striated muscle cell development	5.754138e-6
GO:2000209	regulation of anoikis	5.939543e-6
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	6.080874e-6
GO:0033189	response to vitamin A	6.110530e-6
GO:0009185	ribonucleoside diphosphate metabolic process	7.075758e-6
GO:0090181	regulation of cholesterol metabolic process	7.278884e-6
GO:0043434	response to peptide hormone stimulus	7.488645e-6
GO:0009612	response to mechanical stimulus	8.140235e-6
GO:0007346	regulation of mitotic cell cycle	9.681888e-6
GO:0071295	cellular response to vitamin	1.047253e-5
GO:0033273	response to vitamin	1.202503e-5
GO:0030177	positive regulation of Wnt receptor signaling pathway	1.266828e-5
GO:0009395	phospholipid catabolic process	1.282969e-5
GO:0019285	glycine betaine biosynthetic process from choline	1.370413e-5
GO:0002443	leukocyte mediated immunity	1.445782e-5
GO:0048747	muscle fiber development	1.457863e-5
GO:0032355	response to estradiol stimulus	1.462720e-5
GO:0001649	osteoblast differentiation	1.516374e-5
GO:0006952	defense response	1.571308e-5
GO:0070474	positive regulation of uterine smooth muscle contraction	1.585896e-5
GO:0007320	insemination	1.680591e-5
GO:0019374	galactolipid metabolic process	1.715028e-5
GO:0072087	renal vesicle development	2.090217e-5
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	2.120418e-5
GO:0010193	response to ozone	2.159499e-5
GO:0042542	response to hydrogen peroxide	2.418987e-5
GO:0001558	regulation of cell growth	2.577891e-5
GO:2000210	positive regulation of anoikis	2.666394e-5
GO:0009145	purine nucleoside triphosphate biosynthetic process	2.746559e-5
GO:0045589	regulation of regulatory T cell differentiation	2.841730e-5
GO:0019371	cyclooxygenase pathway	3.043178e-5
GO:0002456	T cell mediated immunity	3.101084e-5
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	3.197835e-5
GO:0009134	nucleoside diphosphate catabolic process	3.265558e-5
GO:0002679	respiratory burst involved in defense response	3.320154e-5
GO:0072668	tubulin complex biogenesis	3.381637e-5
GO:0051704	multi-organism process	3.445982e-5
GO:0032965	regulation of collagen biosynthetic process	3.518468e-5
GO:0000003	reproduction	3.565902e-5
GO:0009201	ribonucleoside triphosphate biosynthetic process	3.593038e-5
GO:0006754	ATP biosynthetic process	3.744706e-5
GO:0090403	oxidative stress-induced premature senescence	3.759974e-5
GO:0032526	response to retinoic acid	3.909427e-5
GO:0008306	associative learning	4.003575e-5
GO:0007620	copulation	4.100198e-5
GO:0006979	response to oxidative stress	4.117467e-5
GO:0046890	regulation of lipid biosynthetic process	4.225436e-5
GO:0022007	convergent extension involved in neural plate elongation	4.460402e-5
GO:0055001	muscle cell development	4.556611e-5
GO:0031670	cellular response to nutrient	4.765343e-5
GO:0051384	response to glucocorticoid stimulus	4.766811e-5
GO:0045918	negative regulation of cytolysis	4.854911e-5
GO:0060029	convergent extension involved in organogenesis	5.184548e-5
GO:0044246	regulation of multicellular organismal metabolic process	5.304923e-5
GO:0007164	establishment of tissue polarity	5.309266e-5
GO:0048668	collateral sprouting	5.366826e-5
GO:0051146	striated muscle cell differentiation	5.981952e-5
GO:0002792	negative regulation of peptide secretion	6.022277e-5
GO:0001934	positive regulation of protein phosphorylation	6.029276e-5
GO:0010718	positive regulation of epithelial to mesenchymal transition	6.045212e-5
GO:0034097	response to cytokine stimulus	6.130315e-5
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	6.359296e-5
GO:0060346	bone trabecula formation	6.401461e-5
GO:0010717	regulation of epithelial to mesenchymal transition	6.442866e-5
GO:0002449	lymphocyte mediated immunity	7.155385e-5
GO:0060026	convergent extension	7.569375e-5
GO:0043589	skin morphogenesis	7.599591e-5
GO:0009142	nucleoside triphosphate biosynthetic process	8.331479e-5
GO:0016998	cell wall macromolecule catabolic process	8.713604e-5
GO:0010350	cellular response to magnesium starvation	8.874947e-5
GO:0048311	mitochondrion distribution	9.396174e-5
GO:0045590	negative regulation of regulatory T cell differentiation	9.507551e-5
GO:0010574	regulation of vascular endothelial growth factor production	1.054272e-4
GO:0090361	regulation of platelet-derived growth factor production	1.081992e-4
GO:0045652	regulation of megakaryocyte differentiation	1.096776e-4
GO:0001798	positive regulation of type IIa hypersensitivity	1.110762e-4
GO:0010866	regulation of triglyceride biosynthetic process	1.153410e-4
GO:0050832	defense response to fungus	1.172799e-4
GO:0050810	regulation of steroid biosynthetic process	1.250549e-4
GO:0050896	response to stimulus	1.271076e-4
GO:0045065	cytotoxic T cell differentiation	1.299849e-4
GO:0045747	positive regulation of Notch signaling pathway	1.355555e-4
GO:0060416	response to growth hormone stimulus	1.386221e-4
GO:0051260	protein homooligomerization	1.400342e-4
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.407231e-4
GO:0006957	complement activation, alternative pathway	1.415383e-4
GO:0022414	reproductive process	1.533564e-4
GO:0002149	hypochlorous acid biosynthetic process	1.549562e-4
GO:0006642	triglyceride mobilization	1.549796e-4
GO:0007606	sensory perception of chemical stimulus	1.594560e-4
GO:0009191	ribonucleoside diphosphate catabolic process	1.594773e-4
GO:0001736	establishment of planar polarity	1.641040e-4
GO:0042692	muscle cell differentiation	1.649453e-4
GO:0007512	adult heart development	1.657589e-4
GO:0055114	oxidation-reduction process	1.700275e-4
GO:0071287	cellular response to manganese ion	1.830683e-4
GO:0001969	regulation of activation of membrane attack complex	1.853804e-4
GO:0048563	post-embryonic organ morphogenesis	1.871159e-4
GO:0090336	positive regulation of brown fat cell differentiation	1.883065e-4
GO:0090362	positive regulation of platelet-derived growth factor production	1.883065e-4
GO:0090271	positive regulation of fibroblast growth factor production	1.883065e-4
GO:0050760	negative regulation of thymidylate synthase biosynthetic process	1.883065e-4
GO:0030111	regulation of Wnt receptor signaling pathway	1.883669e-4
GO:0007568	aging	1.908515e-4
GO:0045860	positive regulation of protein kinase activity	1.915239e-4
GO:0010744	positive regulation of macrophage derived foam cell differentiation	1.952058e-4
GO:0061061	muscle structure development	1.972911e-4
GO:0042221	response to chemical stimulus	1.973208e-4
GO:0048545	response to steroid hormone stimulus	2.041463e-4
GO:0015986	ATP synthesis coupled proton transport	2.042661e-4
GO:0090270	regulation of fibroblast growth factor production	2.184854e-4
GO:0043316	cytotoxic T cell degranulation	2.263085e-4
GO:0045076	regulation of interleukin-2 biosynthetic process	2.264977e-4
GO:0070141	response to UV-A	2.291460e-4
GO:0033182	regulation of histone ubiquitination	2.428192e-4
GO:0000379	tRNA-type intron splice site recognition and cleavage	2.428192e-4
GO:0045066	regulatory T cell differentiation	2.446188e-4
GO:0031064	negative regulation of histone deacetylation	2.476171e-4
GO:0002883	regulation of hypersensitivity	2.515436e-4
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	2.537439e-4
GO:0002309	T cell proliferation involved in immune response	2.558223e-4
GO:0048013	ephrin receptor signaling pathway	2.574593e-4
GO:0007406	negative regulation of neuroblast proliferation	2.724671e-4
GO:0006334	nucleosome assembly	2.791636e-4
GO:0007586	digestion	2.796571e-4
GO:0034694	response to prostaglandin stimulus	3.066970e-4
GO:0030431	sleep	3.092291e-4
GO:0042713	sperm ejaculation	3.106339e-4
GO:0009620	response to fungus	3.133648e-4
GO:0072332	signal transduction by p53 class mediator resulting in induction of apoptosis	3.197935e-4
GO:0009725	response to hormone stimulus	3.205495e-4
GO:0008340	determination of adult lifespan	3.294504e-4
GO:0032859	activation of Ral GTPase activity	3.374583e-4
GO:0046888	negative regulation of hormone secretion	3.391917e-4
GO:0031424	keratinization	3.633429e-4
GO:0002513	tolerance induction to self antigen	3.667550e-4
GO:0043519	regulation of myosin II filament organization	3.701003e-4
GO:0006699	bile acid biosynthetic process	3.701003e-4
GO:0042104	positive regulation of activated T cell proliferation	3.735745e-4
GO:0070252	actin-mediated cell contraction	3.764355e-4
GO:0033275	actin-myosin filament sliding	3.799782e-4
GO:0050863	regulation of T cell activation	3.878448e-4
GO:0022607	cellular component assembly	3.965966e-4
GO:0090179	planar cell polarity pathway involved in neural tube closure	4.018986e-4
GO:0010033	response to organic substance	4.031784e-4
GO:0031032	actomyosin structure organization	4.052498e-4
GO:0031668	cellular response to extracellular stimulus	4.123527e-4
GO:0030035	microspike assembly	4.124726e-4
GO:0010936	negative regulation of macrophage cytokine production	4.143203e-4
GO:0090192	regulation of glomerulus development	4.229484e-4
GO:0045730	respiratory burst	4.281851e-4
GO:0009750	response to fructose stimulus	4.384419e-4
GO:0050974	detection of mechanical stimulus involved in sensory perception	4.538170e-4
GO:0034505	tooth mineralization	4.607422e-4
GO:0007608	sensory perception of smell	4.638007e-4
GO:0043933	macromolecular complex subunit organization	4.813931e-4
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.863662e-4
GO:0055003	cardiac myofibril assembly	4.935369e-4
GO:0019216	regulation of lipid metabolic process	5.126376e-4
GO:0010638	positive regulation of organelle organization	5.144745e-4
GO:0050829	defense response to Gram-negative bacterium	5.174133e-4
GO:0043276	anoikis	5.238384e-4
GO:0033674	positive regulation of kinase activity	5.330124e-4
GO:0070306	lens fiber cell differentiation	5.356468e-4
GO:0030049	muscle filament sliding	5.396750e-4
GO:0050868	negative regulation of T cell activation	5.457713e-4
GO:0010466	negative regulation of peptidase activity	5.461491e-4
GO:0021535	cell migration in hindbrain	5.535749e-4
GO:0050982	detection of mechanical stimulus	5.583302e-4
GO:0071496	cellular response to external stimulus	5.712785e-4
GO:0009605	response to external stimulus	5.715597e-4
GO:0018993	somatic sex determination	5.820755e-4
GO:0001516	prostaglandin biosynthetic process	5.883449e-4
GO:0090278	negative regulation of peptide hormone secretion	5.901345e-4
GO:0032780	negative regulation of ATPase activity	5.939884e-4
GO:0002115	store-operated calcium entry	5.939884e-4
GO:0050954	sensory perception of mechanical stimulus	5.955312e-4
GO:0046676	negative regulation of insulin secretion	6.020904e-4
GO:0001839	neural plate morphogenesis	6.079373e-4
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	6.283244e-4
GO:0043627	response to estrogen stimulus	6.296085e-4
GO:0060632	regulation of microtubule-based movement	6.344908e-4
GO:0010575	positive regulation vascular endothelial growth factor production	6.461255e-4
GO:0044085	cellular component biogenesis	6.728847e-4
GO:0061005	cell differentiation involved in kidney development	6.740623e-4
GO:0003093	regulation of glomerular filtration	6.832442e-4
GO:0009408	response to heat	6.865615e-4
GO:0001970	positive regulation of activation of membrane attack complex	7.041257e-4
GO:0051259	protein oligomerization	7.103769e-4
GO:0034446	substrate adhesion-dependent cell spreading	7.328193e-4
GO:0061302	smooth muscle cell-matrix adhesion	7.336440e-4
GO:0000237	leptotene	7.336440e-4
GO:0015884	folic acid transport	7.346694e-4
GO:0006289	nucleotide-excision repair	7.403910e-4
GO:0072283	metanephric renal vesicle morphogenesis	7.514288e-4
GO:0046882	negative regulation of follicle-stimulating hormone secretion	7.516942e-4
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	7.637624e-4
GO:0045937	positive regulation of phosphate metabolic process	7.709163e-4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	7.730340e-4
GO:0007283	spermatogenesis	7.777966e-4
GO:0006461	protein complex assembly	7.969763e-4
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7.974183e-4
GO:0043029	T cell homeostasis	8.239059e-4
GO:0009152	purine ribonucleotide biosynthetic process	8.260686e-4
GO:0008333	endosome to lysosome transport	8.275421e-4
GO:0065003	macromolecular complex assembly	8.525637e-4
GO:0031282	regulation of guanylate cyclase activity	8.528684e-4
GO:0042327	positive regulation of phosphorylation	8.533326e-4
GO:0006682	galactosylceramide biosynthetic process	8.701108e-4
GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions	8.701108e-4
GO:0009615	response to virus	8.740706e-4
GO:0031669	cellular response to nutrient levels	9.032665e-4
GO:0032383	regulation of intracellular cholesterol transport	9.136968e-4
GO:0002885	positive regulation of hypersensitivity	9.149383e-4
GO:0072161	mesenchymal cell differentiation involved in kidney development	9.172420e-4
GO:0045603	positive regulation of endothelial cell differentiation	9.186607e-4
GO:0048739	cardiac muscle fiber development	9.433816e-4
GO:0072221	metanephric distal convoluted tubule development	9.528560e-4
GO:0051346	negative regulation of hydrolase activity	9.816635e-4
GO:0072202	cell differentiation involved in metanephros development	9.960133e-4
GO:0060047	heart contraction	1.000654e-3
GO:2000758	positive regulation of peptidyl-lysine acetylation	1.005276e-3
GO:0000733	DNA strand renaturation	1.013104e-3
GO:0072143	mesangial cell development	1.013104e-3
GO:0045930	negative regulation of mitotic cell cycle	1.024519e-3
GO:0006283	transcription-coupled nucleotide-excision repair	1.026255e-3
GO:0019376	galactolipid catabolic process	1.035078e-3
GO:0048541	Peyer's patch development	1.037037e-3
GO:0090343	positive regulation of cell aging	1.064311e-3
GO:0070271	protein complex biogenesis	1.095839e-3
GO:0070741	response to interleukin-6	1.105800e-3
GO:0015980	energy derivation by oxidation of organic compounds	1.106261e-3
GO:0010623	developmental programmed cell death	1.111148e-3
GO:0010830	regulation of myotube differentiation	1.112005e-3
GO:0006164	purine nucleotide biosynthetic process	1.130969e-3
GO:0060039	pericardium development	1.162247e-3
GO:0071822	protein complex subunit organization	1.184017e-3
GO:0030317	sperm motility	1.186874e-3
GO:0045933	positive regulation of muscle contraction	1.196150e-3
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.217714e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	1.226682e-3
GO:0048389	intermediate mesoderm development	1.226682e-3
GO:0070498	interleukin-1-mediated signaling pathway	1.236135e-3
GO:0072329	monocarboxylic acid catabolic process	1.248160e-3
GO:0008217	regulation of blood pressure	1.269624e-3
GO:0009101	glycoprotein biosynthetic process	1.273473e-3
GO:0032971	regulation of muscle filament sliding	1.290860e-3
GO:0090030	regulation of steroid hormone biosynthetic process	1.342520e-3
GO:0072422	signal transduction involved in DNA damage checkpoint	1.362651e-3
GO:0042159	lipoprotein catabolic process	1.366239e-3
GO:0001508	regulation of action potential	1.376070e-3
GO:0030252	growth hormone secretion	1.377887e-3
GO:0060324	face development	1.393212e-3
GO:0051705	behavioral interaction between organisms	1.404563e-3
GO:0019049	evasion of host defenses by virus	1.417976e-3
GO:0007522	visceral muscle development	1.429757e-3
GO:0006360	transcription from RNA polymerase I promoter	1.430555e-3
GO:0001840	neural plate development	1.432949e-3
GO:0060325	face morphogenesis	1.448459e-3
GO:0070307	lens fiber cell development	1.450593e-3
GO:0031058	positive regulation of histone modification	1.452053e-3
GO:0030239	myofibril assembly	1.480498e-3
GO:0001967	suckling behavior	1.481166e-3
GO:0072300	positive regulation of metanephric glomerulus development	1.496730e-3
GO:0006631	fatty acid metabolic process	1.600141e-3
GO:0042149	cellular response to glucose starvation	1.605635e-3
GO:0050906	detection of stimulus involved in sensory perception	1.605658e-3
GO:0007618	mating	1.653193e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	1.657369e-3
GO:0030157	pancreatic juice secretion	1.684515e-3
GO:0019369	arachidonic acid metabolic process	1.727613e-3
GO:0006707	cholesterol catabolic process	1.730476e-3
GO:0060685	regulation of prostatic bud formation	1.730476e-3
GO:0006333	chromatin assembly or disassembly	1.736874e-3
GO:0021935	cerebellar granule cell precursor tangential migration	1.748315e-3
GO:0006772	thiamine metabolic process	1.748315e-3
GO:0070207	protein homotrimerization	1.750462e-3
GO:0061360	optic chiasma development	1.804397e-3
GO:2000597	positive regulation of optic nerve formation	1.804397e-3
GO:0035799	ureter maturation	1.804397e-3
GO:0033129	positive regulation of histone phosphorylation	1.804397e-3
GO:0021633	optic nerve structural organization	1.804397e-3
GO:0021650	vestibulocochlear nerve formation	1.804397e-3
GO:0006111	regulation of gluconeogenesis	1.807771e-3
GO:0001957	intramembranous ossification	1.807771e-3
GO:0030854	positive regulation of granulocyte differentiation	1.825606e-3
GO:0035066	positive regulation of histone acetylation	1.844297e-3
GO:0010868	negative regulation of triglyceride biosynthetic process	1.849597e-3
GO:0008015	blood circulation	1.876568e-3
GO:0031063	regulation of histone deacetylation	1.882198e-3
GO:0071731	response to nitric oxide	1.903199e-3
GO:0045668	negative regulation of osteoblast differentiation	1.912633e-3
GO:0022617	extracellular matrix disassembly	1.926043e-3
GO:0042110	T cell activation	1.940410e-3
GO:0042592	homeostatic process	1.943812e-3
GO:0030539	male genitalia development	1.946725e-3
GO:2000178	negative regulation of neural precursor cell proliferation	1.956119e-3
GO:0007154	cell communication	1.959578e-3
GO:0032026	response to magnesium ion	2.014600e-3
GO:0006987	activation of signaling protein activity involved in unfolded protein response	2.037413e-3
GO:0006091	generation of precursor metabolites and energy	2.038322e-3
GO:0021782	glial cell development	2.048009e-3
GO:0034605	cellular response to heat	2.055875e-3
GO:0046031	ADP metabolic process	2.079488e-3
GO:0051046	regulation of secretion	2.102194e-3
GO:0045666	positive regulation of neuron differentiation	2.114247e-3
GO:0045214	sarcomere organization	2.154776e-3
GO:0046034	ATP metabolic process	2.159634e-3
GO:0072077	renal vesicle morphogenesis	2.178319e-3
GO:0051347	positive regulation of transferase activity	2.183273e-3
GO:0006354	transcription elongation, DNA-dependent	2.195044e-3
GO:0009913	epidermal cell differentiation	2.199329e-3
GO:0045077	negative regulation of interferon-gamma biosynthetic process	2.228690e-3
GO:0006540	glutamate decarboxylation to succinate	2.228690e-3
GO:0071827	plasma lipoprotein particle organization	2.235741e-3
GO:0030048	actin filament-based movement	2.256895e-3
GO:0065008	regulation of biological quality	2.283926e-3
GO:0072259	metanephric interstitial cell development	2.312095e-3
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development	2.312095e-3
GO:2000369	regulation of clathrin-mediated endocytosis	2.312095e-3
GO:0072208	metanephric smooth muscle tissue development	2.312095e-3
GO:0072168	specification of anterior mesonephric tubule identity	2.312095e-3
GO:0072169	specification of posterior mesonephric tubule identity	2.312095e-3
GO:0072184	renal vesicle progenitor cell differentiation	2.312095e-3
GO:0006323	DNA packaging	2.346306e-3
GO:0071636	positive regulation of transforming growth factor beta production	2.355470e-3
GO:0048609	multicellular organismal reproductive process	2.374553e-3
GO:0006958	complement activation, classical pathway	2.385427e-3
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	2.405086e-3
GO:0007566	embryo implantation	2.458492e-3
GO:0030154	cell differentiation	2.506103e-3
GO:0019226	transmission of nerve impulse	2.533054e-3
GO:0010458	exit from mitosis	2.573936e-3
GO:0030216	keratinocyte differentiation	2.652490e-3
GO:0050870	positive regulation of T cell activation	2.680701e-3
GO:0090193	positive regulation of glomerulus development	2.690621e-3
GO:0006578	betaine biosynthetic process	2.690621e-3
GO:0070309	lens fiber cell morphogenesis	2.766630e-3
GO:2000594	positive regulation of metanephric DCT cell differentiation	2.783870e-3
GO:2000384	negative regulation of ectoderm development	2.783870e-3
GO:0039003	pronephric field specification	2.783870e-3
GO:0072305	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis	2.783870e-3
GO:0007605	sensory perception of sound	2.788540e-3
GO:0030514	negative regulation of BMP signaling pathway	2.830836e-3
GO:0050957	equilibrioception	2.837188e-3
GO:0090311	regulation of protein deacetylation	2.863794e-3
GO:0010038	response to metal ion	2.864549e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	2.895347e-3
GO:0072017	distal tubule development	2.895672e-3
GO:0010092	specification of organ identity	2.911543e-3
GO:0042840	D-glucuronate catabolic process	2.926330e-3
GO:2001051	positive regulation of tendon cell differentiation	2.926330e-3
GO:0033314	mitotic cell cycle DNA replication checkpoint	2.926330e-3
GO:0051447	negative regulation of meiotic cell cycle	2.926330e-3
GO:0042703	menstruation	2.926330e-3
GO:0032789	unsaturated monocarboxylic acid metabolic process	2.926330e-3
GO:0021509	roof plate formation	2.926330e-3
GO:0019101	female somatic sex determination	2.926330e-3
GO:0032788	saturated monocarboxylic acid metabolic process	2.926330e-3
GO:0033088	negative regulation of immature T cell proliferation in thymus	2.932665e-3
GO:0034383	low-density lipoprotein particle clearance	2.939409e-3
GO:0046466	membrane lipid catabolic process	2.953787e-3
GO:0072522	purine-containing compound biosynthetic process	2.959743e-3
GO:0009260	ribonucleotide biosynthetic process	2.962896e-3
GO:0009132	nucleoside diphosphate metabolic process	2.963520e-3
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	2.970061e-3
GO:0071217	cellular response to external biotic stimulus	2.987140e-3
GO:0070684	seminal clot liquefaction	2.987140e-3
GO:0009617	response to bacterium	2.995257e-3
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	3.039011e-3
GO:0090185	negative regulation of kidney development	3.039011e-3
GO:0042249	establishment of planar polarity of embryonic epithelium	3.039011e-3
GO:0016197	endosome transport	3.058479e-3
GO:0033363	secretory granule organization	3.081697e-3
GO:0006643	membrane lipid metabolic process	3.096000e-3
GO:0007166	cell surface receptor linked signaling pathway	3.108242e-3
GO:0019725	cellular homeostasis	3.112358e-3
GO:0003013	circulatory system process	3.113369e-3
GO:0050670	regulation of lymphocyte proliferation	3.189895e-3
GO:0051225	spindle assembly	3.194550e-3
GO:0035235	ionotropic glutamate receptor signaling pathway	3.199829e-3
GO:0000189	MAPK import into nucleus	3.212357e-3
GO:0007096	regulation of exit from mitosis	3.212410e-3
GO:0071732	cellular response to nitric oxide	3.261396e-3
GO:0060019	radial glial cell differentiation	3.269136e-3
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	3.269136e-3
GO:0052547	regulation of peptidase activity	3.297164e-3
GO:0032944	regulation of mononuclear cell proliferation	3.303054e-3
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	3.373600e-3
GO:0002357	defense response to tumor cell	3.373600e-3
GO:0010701	positive regulation of norepinephrine secretion	3.373600e-3
GO:0022010	central nervous system myelination	3.377645e-3
GO:0009181	purine ribonucleoside diphosphate catabolic process	3.396220e-3
GO:0070663	regulation of leukocyte proliferation	3.411319e-3
GO:0042953	lipoprotein transport	3.472788e-3
GO:0002260	lymphocyte homeostasis	3.486089e-3
GO:0046847	filopodium assembly	3.530512e-3
GO:0046716	muscle cell homeostasis	3.564865e-3
GO:0061113	pancreas morphogenesis	3.578655e-3
GO:0010042	response to manganese ion	3.601697e-3
GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development	3.614298e-3
GO:0031129	inductive cell-cell signaling	3.614298e-3
GO:0060259	regulation of feeding behavior	3.698213e-3
GO:0006638	neutral lipid metabolic process	3.698949e-3
GO:0045766	positive regulation of angiogenesis	3.724500e-3
GO:0014049	positive regulation of glutamate secretion	3.733661e-3
GO:0055013	cardiac muscle cell development	3.789035e-3
GO:0070085	glycosylation	3.792347e-3
GO:0003015	heart process	3.793136e-3
GO:0001776	leukocyte homeostasis	3.793136e-3
GO:0009582	detection of abiotic stimulus	3.841348e-3
GO:0008366	axon ensheathment	3.885258e-3
GO:0014070	response to organic cyclic compound	3.887554e-3
GO:0072162	metanephric mesenchymal cell differentiation	3.923569e-3
GO:0010954	positive regulation of protein processing	3.973573e-3
GO:0009266	response to temperature stimulus	3.977823e-3
GO:0060992	response to fungicide	4.029935e-3
GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	4.075060e-3
GO:0006639	acylglycerol metabolic process	4.079535e-3
GO:0031295	T cell costimulation	4.091410e-3
GO:0042346	positive regulation of NF-kappaB import into nucleus	4.106202e-3
GO:0002250	adaptive immune response	4.127614e-3
GO:0015868	purine ribonucleotide transport	4.161314e-3
GO:0043462	regulation of ATPase activity	4.187163e-3
GO:0002861	regulation of inflammatory response to antigenic stimulus	4.203746e-3
GO:0014074	response to purine-containing compound	4.219310e-3
GO:0051971	positive regulation of transmission of nerve impulse	4.224320e-3
GO:0006172	ADP biosynthetic process	4.229830e-3
GO:0072003	kidney rudiment formation	4.229830e-3
GO:0002791	regulation of peptide secretion	4.267754e-3
GO:0043056	forward locomotion	4.268559e-3
GO:0046006	regulation of activated T cell proliferation	4.288623e-3
GO:0072040	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis	4.296058e-3
GO:0030091	protein repair	4.296058e-3
GO:0033382	maintenance of granzyme B location in T cell secretory granule	4.296058e-3
GO:0033373	maintenance of protease location in mast cell secretory granule	4.296058e-3
GO:0031497	chromatin assembly	4.297905e-3
GO:0060560	developmental growth involved in morphogenesis	4.304598e-3
GO:0072194	kidney smooth muscle tissue development	4.327138e-3
GO:0046340	diacylglycerol catabolic process	4.327138e-3
GO:0006956	complement activation	4.387002e-3
GO:0010935	regulation of macrophage cytokine production	4.388601e-3
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	4.407164e-3
GO:0006950	response to stress	4.509562e-3
GO:0007040	lysosome organization	4.512669e-3
GO:0071103	DNA conformation change	4.610476e-3
GO:0072376	protein activation cascade	4.634305e-3