Novel motif:9

name:	motif9_ANGGCT

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0071260	cellular response to mechanical stimulus	1.951895e-12
GO:0002238	response to molecule of fungal origin	9.592658e-12
GO:0006982	response to lipid hydroperoxide	1.146402e-11
GO:0033233	regulation of protein sumoylation	1.087222e-10
GO:0035814	negative regulation of renal sodium excretion	3.137232e-10
GO:0046626	regulation of insulin receptor signaling pathway	2.403387e-9
GO:0071732	cellular response to nitric oxide	3.195608e-9
GO:0045940	positive regulation of steroid metabolic process	3.832776e-9
GO:0008078	mesodermal cell migration	3.860046e-9
GO:0046627	negative regulation of insulin receptor signaling pathway	3.860222e-9
GO:0033599	regulation of mammary gland epithelial cell proliferation	1.540440e-8
GO:0019884	antigen processing and presentation of exogenous antigen	1.683091e-8
GO:0042074	cell migration involved in gastrulation	2.862108e-8
GO:0050995	negative regulation of lipid catabolic process	3.121014e-8
GO:0035307	positive regulation of protein dephosphorylation	3.202685e-8
GO:0046473	phosphatidic acid metabolic process	4.682349e-8
GO:0031424	keratinization	4.682738e-8
GO:0007509	mesoderm migration involved in gastrulation	4.899533e-8
GO:0045628	regulation of T-helper 2 cell differentiation	5.848793e-8
GO:0033235	positive regulation of protein sumoylation	6.301616e-8
GO:0010832	negative regulation of myotube differentiation	6.934358e-8
GO:0009612	response to mechanical stimulus	7.770410e-8
GO:0006544	glycine metabolic process	9.624584e-8
GO:0014898	cardiac muscle hypertrophy in response to stress	1.074597e-7
GO:0071496	cellular response to external stimulus	1.207446e-7
GO:0071214	cellular response to abiotic stimulus	1.231659e-7
GO:0035306	positive regulation of dephosphorylation	1.247739e-7
GO:0014874	response to stimulus involved in regulation of muscle adaptation	1.304818e-7
GO:0048771	tissue remodeling	1.515505e-7
GO:0042744	hydrogen peroxide catabolic process	1.563216e-7
GO:0002439	chronic inflammatory response to antigenic stimulus	1.597696e-7
GO:0002437	inflammatory response to antigenic stimulus	2.742831e-7
GO:0021526	medial motor column neuron differentiation	3.243118e-7
GO:0009895	negative regulation of catabolic process	3.991848e-7
GO:0060708	spongiotrophoblast differentiation	4.260612e-7
GO:0034333	adherens junction assembly	4.310042e-7
GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	4.369791e-7
GO:0002703	regulation of leukocyte mediated immunity	4.461929e-7
GO:0001885	endothelial cell development	4.953422e-7
GO:0051154	negative regulation of striated muscle cell differentiation	6.028052e-7
GO:0034616	response to laminar fluid shear stress	6.402527e-7
GO:0002513	tolerance induction to self antigen	6.411870e-7
GO:0045576	mast cell activation	7.021085e-7
GO:0006884	cell volume homeostasis	7.915334e-7
GO:0014888	striated muscle adaptation	8.356913e-7
GO:0070327	thyroid hormone transport	8.379059e-7
GO:0060349	bone morphogenesis	8.783262e-7
GO:0002274	myeloid leukocyte activation	9.989604e-7
GO:0035304	regulation of protein dephosphorylation	9.999691e-7
GO:0009069	serine family amino acid metabolic process	1.014835e-6
GO:0061028	establishment of endothelial barrier	1.057802e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.125250e-6
GO:0072109	glomerular mesangium development	1.158313e-6
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	1.219030e-6
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.499006e-6
GO:0060620	regulation of cholesterol import	1.640952e-6
GO:0051591	response to cAMP	1.643629e-6
GO:0071731	response to nitric oxide	1.680757e-6
GO:0032720	negative regulation of tumor necrosis factor production	1.841573e-6
GO:0045623	negative regulation of T-helper cell differentiation	1.843821e-6
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	1.995953e-6
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	2.017769e-6
GO:0045833	negative regulation of lipid metabolic process	2.238527e-6
GO:0003158	endothelium development	2.409502e-6
GO:0002708	positive regulation of lymphocyte mediated immunity	2.493608e-6
GO:0002711	positive regulation of T cell mediated immunity	2.663504e-6
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	2.702021e-6
GO:0050902	leukocyte adhesive activation	2.702021e-6
GO:0050779	RNA destabilization	2.722927e-6
GO:0070670	response to interleukin-4	2.728708e-6
GO:0045581	negative regulation of T cell differentiation	2.752363e-6
GO:0007096	regulation of exit from mitosis	2.864352e-6
GO:0003009	skeletal muscle contraction	2.895947e-6
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	2.973329e-6
GO:0045065	cytotoxic T cell differentiation	2.999807e-6
GO:0070849	response to epidermal growth factor stimulus	3.001617e-6
GO:0006545	glycine biosynthetic process	3.129096e-6
GO:0045638	negative regulation of myeloid cell differentiation	3.182338e-6
GO:0010987	negative regulation of high-density lipoprotein particle clearance	3.232004e-6
GO:0010897	negative regulation of triglyceride catabolic process	3.232004e-6
GO:0010893	positive regulation of steroid biosynthetic process	3.269852e-6
GO:0014050	negative regulation of glutamate secretion	3.366461e-6
GO:0006654	phosphatidic acid biosynthetic process	3.414845e-6
GO:0033044	regulation of chromosome organization	4.406649e-6
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	4.801393e-6
GO:0070555	response to interleukin-1	5.477348e-6
GO:0006694	steroid biosynthetic process	5.502602e-6
GO:0043471	regulation of cellular carbohydrate catabolic process	5.786576e-6
GO:0060033	anatomical structure regression	6.260370e-6
GO:0030204	chondroitin sulfate metabolic process	6.315676e-6
GO:0045647	negative regulation of erythrocyte differentiation	6.427873e-6
GO:0046724	oxalic acid secretion	7.032894e-6
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	7.032894e-6
GO:0034116	positive regulation of heterotypic cell-cell adhesion	7.122146e-6
GO:0046639	negative regulation of alpha-beta T cell differentiation	7.280223e-6
GO:0070071	proton-transporting two-sector ATPase complex assembly	7.421569e-6
GO:0002449	lymphocyte mediated immunity	7.532550e-6
GO:0050727	regulation of inflammatory response	7.604334e-6
GO:0045908	negative regulation of vasodilation	7.751028e-6
GO:0031064	negative regulation of histone deacetylation	7.850329e-6
GO:0072110	glomerular mesangial cell proliferation	7.888420e-6
GO:0002443	leukocyte mediated immunity	8.321196e-6
GO:0048630	skeletal muscle tissue growth	8.921694e-6
GO:0032204	regulation of telomere maintenance	9.912566e-6
GO:0045630	positive regulation of T-helper 2 cell differentiation	1.079163e-5
GO:0015695	organic cation transport	1.096787e-5
GO:0002719	negative regulation of cytokine production involved in immune response	1.098202e-5
GO:0019048	virus-host interaction	1.105763e-5
GO:0001766	membrane raft polarization	1.140341e-5
GO:0043503	skeletal muscle fiber adaptation	1.142194e-5
GO:0060621	negative regulation of cholesterol import	1.169165e-5
GO:0046006	regulation of activated T cell proliferation	1.171571e-5
GO:0043500	muscle adaptation	1.218089e-5
GO:0045622	regulation of T-helper cell differentiation	1.244668e-5
GO:0070301	cellular response to hydrogen peroxide	1.394450e-5
GO:0006685	sphingomyelin catabolic process	1.401288e-5
GO:0043249	erythrocyte maturation	1.436241e-5
GO:0060712	spongiotrophoblast layer development	1.443127e-5
GO:0042108	positive regulation of cytokine biosynthetic process	1.547913e-5
GO:0045820	negative regulation of glycolysis	1.601555e-5
GO:0009650	UV protection	1.629307e-5
GO:0033129	positive regulation of histone phosphorylation	1.637523e-5
GO:0071347	cellular response to interleukin-1	1.651271e-5
GO:0030206	chondroitin sulfate biosynthetic process	1.726104e-5
GO:0042482	positive regulation of odontogenesis	1.767629e-5
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	1.778826e-5
GO:0002706	regulation of lymphocyte mediated immunity	1.780575e-5
GO:0005981	regulation of glycogen catabolic process	1.800335e-5
GO:0030593	neutrophil chemotaxis	1.816096e-5
GO:0032729	positive regulation of interferon-gamma production	1.865767e-5
GO:0051043	regulation of membrane protein ectodomain proteolysis	1.913503e-5
GO:0032526	response to retinoic acid	2.021905e-5
GO:0003300	cardiac muscle hypertrophy	2.086096e-5
GO:0016311	dephosphorylation	2.124572e-5
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	2.298084e-5
GO:0009817	defense response to fungus, incompatible interaction	2.298084e-5
GO:0032753	positive regulation of interleukin-4 production	2.415402e-5
GO:0046543	development of secondary female sexual characteristics	2.427448e-5
GO:0051532	regulation of NFAT protein import into nucleus	2.453264e-5
GO:0032981	mitochondrial respiratory chain complex I assembly	2.486853e-5
GO:0042104	positive regulation of activated T cell proliferation	2.579318e-5
GO:0010829	negative regulation of glucose transport	2.581050e-5
GO:0010830	regulation of myotube differentiation	2.588162e-5
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	2.639733e-5
GO:0051168	nuclear export	2.756707e-5
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	2.822040e-5
GO:0045076	regulation of interleukin-2 biosynthetic process	2.929580e-5
GO:0051896	regulation of protein kinase B signaling cascade	2.992384e-5
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	3.012804e-5
GO:0032649	regulation of interferon-gamma production	3.146956e-5
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3.275958e-5
GO:0072126	positive regulation of glomerular mesangial cell proliferation	3.395979e-5
GO:0071506	cellular response to mycophenolic acid	3.395979e-5
GO:0006417	regulation of translation	3.421898e-5
GO:0010872	regulation of cholesterol esterification	3.665033e-5
GO:0031330	negative regulation of cellular catabolic process	3.679309e-5
GO:0033189	response to vitamin A	3.902214e-5
GO:0016126	sterol biosynthetic process	3.919021e-5
GO:0033108	mitochondrial respiratory chain complex assembly	4.031838e-5
GO:0031440	regulation of mRNA 3'-end processing	4.068224e-5
GO:0045590	negative regulation of regulatory T cell differentiation	4.093079e-5
GO:0030388	fructose 1,6-bisphosphate metabolic process	4.093151e-5
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	4.098945e-5
GO:0014894	response to denervation involved in regulation of muscle adaptation	4.129076e-5
GO:0002089	lens morphogenesis in camera-type eye	4.144432e-5
GO:0045176	apical protein localization	4.209741e-5
GO:0002699	positive regulation of immune effector process	4.247489e-5
GO:0046849	bone remodeling	4.257849e-5
GO:0001817	regulation of cytokine production	4.326122e-5
GO:0042117	monocyte activation	4.334391e-5
GO:0045446	endothelial cell differentiation	4.372980e-5
GO:0019087	transformation of host cell by virus	4.413305e-5
GO:0090130	tissue migration	4.542571e-5
GO:0052509	positive regulation by symbiont of host defense response	4.664984e-5
GO:0044341	sodium-dependent phosphate transport	4.911549e-5
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.028418e-5
GO:0043029	T cell homeostasis	5.431272e-5
GO:0030853	negative regulation of granulocyte differentiation	5.507458e-5
GO:0008624	induction of apoptosis by extracellular signals	5.549205e-5
GO:0006684	sphingomyelin metabolic process	5.736961e-5
GO:0042797	tRNA transcription from RNA polymerase III promoter	5.819338e-5
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	5.819338e-5
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	5.876526e-5
GO:0043094	cellular metabolic compound salvage	5.966923e-5
GO:0045061	thymic T cell selection	6.225512e-5
GO:0002478	antigen processing and presentation of exogenous peptide antigen	6.389234e-5
GO:0043932	ossification involved in bone remodeling	6.410347e-5
GO:0010529	negative regulation of transposition	6.482062e-5
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	6.612315e-5
GO:0051781	positive regulation of cell division	6.794227e-5
GO:0050830	defense response to Gram-positive bacterium	6.800591e-5
GO:0045626	negative regulation of T-helper 1 cell differentiation	6.870931e-5
GO:0002740	negative regulation of cytokine secretion involved in immune response	6.965689e-5
GO:0006107	oxaloacetate metabolic process	7.097836e-5
GO:0034340	response to type I interferon	7.102702e-5
GO:0032581	ER-dependent peroxisome organization	7.201417e-5
GO:0010799	regulation of peptidyl-threonine phosphorylation	7.203637e-5
GO:0030865	cortical cytoskeleton organization	7.549804e-5
GO:0006348	chromatin silencing at telomere	7.598519e-5
GO:0002889	regulation of immunoglobulin mediated immune response	7.703725e-5
GO:0046730	induction of host immune response by virus	7.729177e-5
GO:0023021	termination of signal transduction	7.981730e-5
GO:0010624	regulation of Schwann cell proliferation	8.121365e-5
GO:0045651	positive regulation of macrophage differentiation	8.124467e-5
GO:0031063	regulation of histone deacetylation	8.130398e-5
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	8.244363e-5
GO:0032689	negative regulation of interferon-gamma production	8.455674e-5
GO:0033590	response to cobalamin	8.475524e-5
GO:0006117	acetaldehyde metabolic process	8.475524e-5
GO:0050654	chondroitin sulfate proteoglycan metabolic process	8.565601e-5
GO:0043415	positive regulation of skeletal muscle tissue regeneration	8.800026e-5
GO:0042137	sequestering of neurotransmitter	8.976293e-5
GO:0010742	macrophage derived foam cell differentiation	8.992103e-5
GO:0010873	positive regulation of cholesterol esterification	9.069580e-5
GO:0006700	C21-steroid hormone biosynthetic process	9.453666e-5
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	9.681422e-5
GO:0016973	poly(A)+ mRNA export from nucleus	9.831413e-5
GO:0010939	regulation of necrotic cell death	9.990507e-5
GO:0042335	cuticle development	1.009266e-4
GO:0009070	serine family amino acid biosynthetic process	1.031502e-4
GO:0006290	pyrimidine dimer repair	1.082372e-4
GO:0060707	trophoblast giant cell differentiation	1.094137e-4
GO:0060337	type I interferon-mediated signaling pathway	1.096264e-4
GO:0051302	regulation of cell division	1.112743e-4
GO:0042304	regulation of fatty acid biosynthetic process	1.115495e-4
GO:0009303	rRNA transcription	1.127682e-4
GO:0010626	negative regulation of Schwann cell proliferation	1.172027e-4
GO:0032365	intracellular lipid transport	1.204648e-4
GO:0071356	cellular response to tumor necrosis factor	1.231779e-4
GO:0014805	smooth muscle adaptation	1.234089e-4
GO:0035066	positive regulation of histone acetylation	1.235869e-4
GO:0033326	cerebrospinal fluid secretion	1.236901e-4
GO:0046827	positive regulation of protein export from nucleus	1.239657e-4
GO:0031442	positive regulation of mRNA 3'-end processing	1.244807e-4
GO:0019532	oxalate transport	1.246849e-4
GO:0010940	positive regulation of necrotic cell death	1.271322e-4
GO:0007253	cytoplasmic sequestering of NF-kappaB	1.281573e-4
GO:0051665	membrane raft localization	1.348045e-4
GO:0006942	regulation of striated muscle contraction	1.356660e-4
GO:0046134	pyrimidine nucleoside biosynthetic process	1.358473e-4
GO:0051534	negative regulation of NFAT protein import into nucleus	1.383297e-4
GO:0060644	mammary gland epithelial cell differentiation	1.439860e-4
GO:0045637	regulation of myeloid cell differentiation	1.441877e-4
GO:0045066	regulatory T cell differentiation	1.445865e-4
GO:0042542	response to hydrogen peroxide	1.449157e-4
GO:0032355	response to estradiol stimulus	1.483375e-4
GO:0002712	regulation of B cell mediated immunity	1.499054e-4
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.500828e-4
GO:0035572	N-terminal peptidyl-serine dimethylation	1.500828e-4
GO:0035573	N-terminal peptidyl-serine trimethylation	1.500828e-4
GO:0018016	N-terminal peptidyl-proline dimethylation	1.500828e-4
GO:0060262	negative regulation of N-terminal protein palmitoylation	1.560963e-4
GO:0045980	negative regulation of nucleotide metabolic process	1.626824e-4
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	1.674716e-4
GO:0043585	nose morphogenesis	1.731105e-4
GO:0006927	transformed cell apoptosis	1.731105e-4
GO:0046108	uridine metabolic process	1.732972e-4
GO:0042742	defense response to bacterium	1.788781e-4
GO:0060178	regulation of exocyst localization	1.820037e-4
GO:0001928	regulation of exocyst assembly	1.820037e-4
GO:0033273	response to vitamin	1.848102e-4
GO:0050776	regulation of immune response	1.861018e-4
GO:0060348	bone development	1.874037e-4
GO:0006695	cholesterol biosynthetic process	1.958025e-4
GO:0030225	macrophage differentiation	1.962234e-4
GO:0015693	magnesium ion transport	1.993553e-4
GO:0045922	negative regulation of fatty acid metabolic process	2.012793e-4
GO:0071460	cellular response to cell-matrix adhesion	2.016720e-4
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	2.019031e-4
GO:0034114	regulation of heterotypic cell-cell adhesion	2.019031e-4
GO:0052200	response to host defenses	2.042723e-4
GO:0006521	regulation of cellular amino acid metabolic process	2.165215e-4
GO:0060754	positive regulation of mast cell chemotaxis	2.170527e-4
GO:0015850	organic alcohol transport	2.173183e-4
GO:0006909	phagocytosis	2.173435e-4
GO:0017148	negative regulation of translation	2.178568e-4
GO:0006471	protein ADP-ribosylation	2.283586e-4
GO:0033238	regulation of cellular amine metabolic process	2.350341e-4
GO:0033159	negative regulation of protein import into nucleus, translocation	2.352943e-4
GO:0048144	fibroblast proliferation	2.352943e-4
GO:0070164	negative regulation of adiponectin secretion	2.417429e-4
GO:0060355	positive regulation of cell adhesion molecule production	2.417429e-4
GO:0035505	positive regulation of myosin light chain kinase activity	2.417429e-4
GO:0051897	positive regulation of protein kinase B signaling cascade	2.418197e-4
GO:0060744	mammary gland branching involved in thelarche	2.419002e-4
GO:0009395	phospholipid catabolic process	2.456341e-4
GO:0033194	response to hydroperoxide	2.456872e-4
GO:0071803	positive regulation of podosome assembly	2.520145e-4
GO:0003108	negative regulation of the force of heart contraction by chemical signal	2.520145e-4
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.530646e-4
GO:0045084	positive regulation of interleukin-12 biosynthetic process	2.564720e-4
GO:0021773	striatal medium spiny neuron differentiation	2.566427e-4
GO:0045589	regulation of regulatory T cell differentiation	2.566427e-4
GO:0035065	regulation of histone acetylation	2.598774e-4
GO:0000244	assembly of spliceosomal tri-snRNP	2.610942e-4
GO:0070669	response to interleukin-2	2.682121e-4
GO:0006449	regulation of translational termination	2.683954e-4
GO:0002718	regulation of cytokine production involved in immune response	2.748235e-4
GO:0006188	IMP biosynthetic process	2.842449e-4
GO:0030866	cortical actin cytoskeleton organization	2.873024e-4
GO:0009620	response to fungus	2.952110e-4
GO:0060391	positive regulation of SMAD protein import into nucleus	2.978060e-4
GO:0031297	replication fork processing	2.989875e-4
GO:0042035	regulation of cytokine biosynthetic process	2.995250e-4
GO:0045556	positive regulation of TRAIL biosynthetic process	2.997641e-4
GO:0015874	norepinephrine transport	2.997641e-4
GO:0002698	negative regulation of immune effector process	2.999066e-4
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	3.037041e-4
GO:0046732	active induction of host immune response by virus	3.037766e-4
GO:0002250	adaptive immune response	3.052967e-4
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	3.126109e-4
GO:0000387	spliceosomal snRNP assembly	3.162628e-4
GO:0070307	lens fiber cell development	3.170462e-4
GO:0051937	catecholamine transport	3.272106e-4
GO:0022010	central nervous system myelination	3.306742e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	3.321970e-4
GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly	3.462878e-4
GO:0032715	negative regulation of interleukin-6 production	3.493796e-4
GO:0035229	positive regulation of glutamate-cysteine ligase activity	3.495398e-4
GO:0006611	protein export from nucleus	3.590169e-4
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	3.609892e-4
GO:0043574	peroxisomal transport	3.642471e-4
GO:0010523	negative regulation of calcium ion transport into cytosol	3.689813e-4
GO:0006405	RNA export from nucleus	3.732347e-4
GO:0048813	dendrite morphogenesis	3.746407e-4
GO:0002821	positive regulation of adaptive immune response	3.851737e-4
GO:0034329	cell junction assembly	3.903022e-4
GO:0043304	regulation of mast cell degranulation	3.931554e-4
GO:0006853	carnitine shuttle	3.938945e-4
GO:0045073	regulation of chemokine biosynthetic process	4.182717e-4
GO:0051384	response to glucocorticoid stimulus	4.292715e-4
GO:0097107	postsynaptic density assembly	4.306134e-4
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	4.306134e-4
GO:0071104	response to interleukin-9	4.306134e-4
GO:0003331	positive regulation of extracellular matrix constituent secretion	4.306134e-4
GO:0061049	cell growth involved in cardiac muscle cell development	4.306134e-4
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	4.306134e-4
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	4.306134e-4
GO:0008625	induction of apoptosis via death domain receptors	4.331134e-4
GO:0032370	positive regulation of lipid transport	4.378725e-4
GO:0043163	cell envelope organization	4.497320e-4
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	4.497320e-4
GO:0033860	regulation of NAD(P)H oxidase activity	4.497320e-4
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	4.614331e-4
GO:0018963	phthalate metabolic process	4.636702e-4
GO:0090311	regulation of protein deacetylation	4.642800e-4
GO:0060390	regulation of SMAD protein import into nucleus	4.715440e-4
GO:0042493	response to drug	4.723767e-4
GO:0044062	regulation of excretion	4.745868e-4
GO:0042743	hydrogen peroxide metabolic process	4.778165e-4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	4.896154e-4
GO:0030217	T cell differentiation	4.949817e-4
GO:0071276	cellular response to cadmium ion	4.957372e-4
GO:0002019	regulation of renal output by angiotensin	5.159097e-4
GO:0048872	homeostasis of number of cells	5.224544e-4
GO:0010610	regulation of mRNA stability involved in response to stress	5.265638e-4
GO:0033209	tumor necrosis factor-mediated signaling pathway	5.361571e-4
GO:0006691	leukotriene metabolic process	5.399727e-4
GO:0060996	dendritic spine development	5.404047e-4
GO:0006625	protein targeting to peroxisome	5.404047e-4
GO:0060611	mammary gland fat development	5.493065e-4
GO:0046173	polyol biosynthetic process	5.493065e-4
GO:0019049	evasion of host defenses by virus	5.500878e-4
GO:0032674	regulation of interleukin-5 production	5.614188e-4
GO:0003417	growth plate cartilage development	5.662074e-4
GO:0071870	cellular response to catecholamine stimulus	5.667304e-4
GO:0045905	positive regulation of translational termination	5.667304e-4
GO:0045901	positive regulation of translational elongation	5.667304e-4
GO:0006452	translational frameshifting	5.667304e-4
GO:0032892	positive regulation of organic acid transport	5.773925e-4
GO:0010982	regulation of high-density lipoprotein particle clearance	5.820420e-4
GO:0030730	sequestering of triglyceride	5.890564e-4
GO:0045086	positive regulation of interleukin-2 biosynthetic process	5.911313e-4
GO:0045994	positive regulation of translational initiation by iron	5.913001e-4
GO:0002037	negative regulation of L-glutamate transport	5.913001e-4
GO:0070375	BMK cascade	5.981001e-4
GO:0046645	positive regulation of gamma-delta T cell activation	5.983799e-4
GO:0045080	positive regulation of chemokine biosynthetic process	5.989670e-4
GO:0030852	regulation of granulocyte differentiation	6.020882e-4
GO:0021658	rhombomere 3 morphogenesis	6.132175e-4
GO:0071705	nitrogen compound transport	6.227037e-4
GO:0043380	regulation of memory T cell differentiation	6.277991e-4
GO:0009991	response to extracellular stimulus	6.303959e-4
GO:0018879	biphenyl metabolic process	6.304500e-4
GO:0071280	cellular response to copper ion	6.416861e-4
GO:0048839	inner ear development	6.428739e-4
GO:0009235	cobalamin metabolic process	6.498730e-4
GO:0045717	negative regulation of fatty acid biosynthetic process	6.513671e-4
GO:0007585	respiratory gaseous exchange	6.539918e-4
GO:0014070	response to organic cyclic compound	6.569549e-4
GO:0019060	intracellular transport of viral proteins in host cell	6.585369e-4
GO:0006749	glutathione metabolic process	6.634498e-4
GO:0010034	response to acetate	6.660072e-4
GO:0048569	post-embryonic organ development	6.709849e-4
GO:0033683	nucleotide-excision repair, DNA incision	6.838142e-4
GO:0031296	B cell costimulation	6.947089e-4
GO:0031104	dendrite regeneration	6.947089e-4
GO:0031960	response to corticosteroid stimulus	6.969457e-4
GO:0034384	high-density lipoprotein particle clearance	6.982524e-4
GO:0015872	dopamine transport	7.010737e-4
GO:0045588	positive regulation of gamma-delta T cell differentiation	7.017080e-4
GO:0002679	respiratory burst involved in defense response	7.075463e-4
GO:0009635	response to herbicide	7.087808e-4
GO:0051092	positive regulation of NF-kappaB transcription factor activity	7.127783e-4
GO:0003416	endochondral bone growth	7.205879e-4
GO:0001909	leukocyte mediated cytotoxicity	7.351736e-4
GO:0031347	regulation of defense response	7.370630e-4
GO:0048298	positive regulation of isotype switching to IgA isotypes	7.614110e-4
GO:0014829	vascular smooth muscle contraction	7.661973e-4
GO:0032515	negative regulation of phosphoprotein phosphatase activity	7.766940e-4
GO:0002682	regulation of immune system process	7.878675e-4
GO:0032210	regulation of telomere maintenance via telomerase	7.999275e-4
GO:0002828	regulation of type 2 immune response	8.094000e-4
GO:0045624	positive regulation of T-helper cell differentiation	8.111679e-4
GO:0042267	natural killer cell mediated cytotoxicity	8.220215e-4
GO:0051004	regulation of lipoprotein lipase activity	8.362900e-4
GO:0014012	peripheral nervous system axon regeneration	8.579984e-4
GO:0042994	cytoplasmic sequestering of transcription factor	8.637364e-4
GO:0070163	regulation of adiponectin secretion	8.649280e-4
GO:0044240	multicellular organismal lipid catabolic process	8.697774e-4
GO:0006689	ganglioside catabolic process	8.746573e-4
GO:0050778	positive regulation of immune response	8.788156e-4
GO:0043174	nucleoside salvage	8.837584e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	8.841795e-4
GO:0050710	negative regulation of cytokine secretion	8.843550e-4
GO:0045625	regulation of T-helper 1 cell differentiation	8.852737e-4
GO:0040040	thermosensory behavior	8.860205e-4
GO:0061053	somite development	8.914672e-4
GO:0043300	regulation of leukocyte degranulation	8.943061e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	8.999433e-4
GO:0045136	development of secondary sexual characteristics	9.157388e-4
GO:0032226	positive regulation of synaptic transmission, dopaminergic	9.236201e-4
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	9.254484e-4
GO:0019724	B cell mediated immunity	9.385268e-4
GO:0050994	regulation of lipid catabolic process	9.397650e-4
GO:0022415	viral reproductive process	9.547912e-4
GO:0031667	response to nutrient levels	9.591457e-4
GO:0015670	carbon dioxide transport	9.605507e-4
GO:0045629	negative regulation of T-helper 2 cell differentiation	9.607973e-4
GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	9.725688e-4
GO:0001756	somitogenesis	9.885943e-4
GO:0061302	smooth muscle cell-matrix adhesion	1.004620e-3
GO:0006669	sphinganine-1-phosphate biosynthetic process	1.004620e-3
GO:0045472	response to ether	1.004620e-3
GO:0032736	positive regulation of interleukin-13 production	1.014066e-3
GO:0015837	amine transport	1.034698e-3
GO:0006000	fructose metabolic process	1.059393e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	1.062354e-3
GO:0033700	phospholipid efflux	1.071664e-3
GO:0021569	rhombomere 3 development	1.081506e-3
GO:0019218	regulation of steroid metabolic process	1.090610e-3
GO:0007422	peripheral nervous system development	1.103374e-3
GO:0045060	negative thymic T cell selection	1.113728e-3
GO:0021782	glial cell development	1.122306e-3
GO:0072337	modified amino acid transport	1.138073e-3
GO:0002252	immune effector process	1.140994e-3
GO:0034330	cell junction organization	1.143280e-3
GO:0006261	DNA-dependent DNA replication	1.156658e-3
GO:0045006	DNA deamination	1.161216e-3
GO:0043973	histone H3-K4 acetylation	1.176442e-3
GO:0046985	positive regulation of hemoglobin biosynthetic process	1.176442e-3
GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	1.176442e-3
GO:0045580	regulation of T cell differentiation	1.180091e-3
GO:0009113	purine base biosynthetic process	1.185841e-3
GO:0042487	regulation of odontogenesis of dentine-containing tooth	1.190383e-3
GO:0002724	regulation of T cell cytokine production	1.190383e-3
GO:0000302	response to reactive oxygen species	1.195307e-3
GO:0000093	mitotic telophase	1.195890e-3
GO:0007109	cytokinesis, completion of separation	1.198873e-3
GO:0045835	negative regulation of meiosis	1.201076e-3
GO:0046637	regulation of alpha-beta T cell differentiation	1.230484e-3
GO:0070383	DNA cytosine deamination	1.260684e-3
GO:0035461	vitamin transmembrane transport	1.261344e-3
GO:0035470	positive regulation of vascular wound healing	1.261344e-3
GO:0015747	urate transport	1.261344e-3
GO:0014896	muscle hypertrophy	1.262107e-3
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	1.269689e-3
GO:0015879	carnitine transport	1.274455e-3
GO:0045945	positive regulation of transcription from RNA polymerase III promoter	1.280451e-3
GO:0006855	drug transmembrane transport	1.280451e-3
GO:0034224	cellular response to zinc ion starvation	1.292161e-3
GO:0032212	positive regulation of telomere maintenance via telomerase	1.306226e-3
GO:0010226	response to lithium ion	1.325037e-3
GO:0051220	cytoplasmic sequestering of protein	1.334950e-3
GO:0042756	drinking behavior	1.337584e-3
GO:0006021	inositol biosynthetic process	1.358852e-3
GO:0006636	unsaturated fatty acid biosynthetic process	1.378061e-3
GO:0060133	somatotropin secreting cell development	1.387504e-3
GO:0001805	positive regulation of type III hypersensitivity	1.387504e-3
GO:0002431	Fc receptor mediated stimulatory signaling pathway	1.387504e-3
GO:0033127	regulation of histone phosphorylation	1.392004e-3
GO:0034375	high-density lipoprotein particle remodeling	1.412272e-3
GO:0046463	acylglycerol biosynthetic process	1.412631e-3
GO:0019264	glycine biosynthetic process from serine	1.457107e-3
GO:0006892	post-Golgi vesicle-mediated transport	1.464736e-3
GO:0032673	regulation of interleukin-4 production	1.468538e-3
GO:0016255	attachment of GPI anchor to protein	1.490699e-3
GO:0045599	negative regulation of fat cell differentiation	1.493179e-3
GO:0046340	diacylglycerol catabolic process	1.499211e-3
GO:0045988	negative regulation of striated muscle contraction	1.520163e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0042744	hydrogen peroxide catabolic process	5.185306e-13
GO:0030300	regulation of intestinal cholesterol absorption	6.269787e-12
GO:0002385	mucosal immune response	3.144490e-11
GO:0032321	positive regulation of Rho GTPase activity	5.482296e-11
GO:0002251	organ or tissue specific immune response	1.130536e-10
GO:0043088	regulation of Cdc42 GTPase activity	1.175023e-10
GO:0044240	multicellular organismal lipid catabolic process	1.562778e-10
GO:0043089	positive regulation of Cdc42 GTPase activity	1.974241e-10
GO:0048298	positive regulation of isotype switching to IgA isotypes	5.720533e-10
GO:0043154	negative regulation of caspase activity	1.820626e-9
GO:0006982	response to lipid hydroperoxide	6.592508e-9
GO:0055090	acylglycerol homeostasis	1.369111e-8
GO:0010896	regulation of triglyceride catabolic process	1.576552e-8
GO:0002227	innate immune response in mucosa	3.485934e-8
GO:0032319	regulation of Rho GTPase activity	4.706419e-8
GO:0043547	positive regulation of GTPase activity	5.275439e-8
GO:0042743	hydrogen peroxide metabolic process	5.550129e-8
GO:0007021	tubulin complex assembly	8.067072e-8
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	9.517364e-8
GO:0015914	phospholipid transport	9.968131e-8
GO:0042992	negative regulation of transcription factor import into nucleus	2.079397e-7
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	2.591253e-7
GO:0033344	cholesterol efflux	2.781950e-7
GO:0050748	negative regulation of lipoprotein metabolic process	3.611338e-7
GO:0072593	reactive oxygen species metabolic process	5.015003e-7
GO:0010898	positive regulation of triglyceride catabolic process	5.438222e-7
GO:0033700	phospholipid efflux	5.628779e-7
GO:0050994	regulation of lipid catabolic process	5.646225e-7
GO:0045662	negative regulation of myoblast differentiation	5.864532e-7
GO:0010873	positive regulation of cholesterol esterification	6.009654e-7
GO:0046470	phosphatidylcholine metabolic process	8.137549e-7
GO:0051534	negative regulation of NFAT protein import into nucleus	1.038935e-6
GO:0051403	stress-activated MAPK cascade	1.075540e-6
GO:0035306	positive regulation of dephosphorylation	2.587709e-6
GO:0007602	phototransduction	3.240900e-6
GO:0042994	cytoplasmic sequestering of transcription factor	3.556745e-6
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	3.703554e-6
GO:0042308	negative regulation of protein import into nucleus	4.125133e-6
GO:0035307	positive regulation of protein dephosphorylation	4.153450e-6
GO:0050764	regulation of phagocytosis	4.370106e-6
GO:0032862	activation of Rho GTPase activity	4.498705e-6
GO:0051006	positive regulation of lipoprotein lipase activity	4.665190e-6
GO:0032374	regulation of cholesterol transport	4.992785e-6
GO:0032864	activation of Cdc42 GTPase activity	5.147134e-6
GO:0051004	regulation of lipoprotein lipase activity	5.264659e-6
GO:0051336	regulation of hydrolase activity	5.790691e-6
GO:0050766	positive regulation of phagocytosis	6.117115e-6
GO:0044058	regulation of digestive system process	6.510056e-6
GO:0034442	regulation of lipoprotein oxidation	6.525756e-6
GO:0044241	lipid digestion	6.564297e-6
GO:0014047	glutamate secretion	6.594171e-6
GO:0046940	nucleoside monophosphate phosphorylation	7.208521e-6
GO:0050668	positive regulation of homocysteine metabolic process	7.208521e-6
GO:0045796	negative regulation of intestinal cholesterol absorption	7.208521e-6
GO:0045963	negative regulation of dopamine metabolic process	7.208521e-6
GO:0010949	negative regulation of intestinal phytosterol absorption	7.208521e-6
GO:0051148	negative regulation of muscle cell differentiation	1.119937e-5
GO:0006540	glutamate decarboxylation to succinate	1.136016e-5
GO:0002155	regulation of thyroid hormone mediated signaling pathway	1.136016e-5
GO:2000826	regulation of heart morphogenesis	1.246123e-5
GO:0046530	photoreceptor cell differentiation	1.274645e-5
GO:0000305	response to oxygen radical	1.301674e-5
GO:0032210	regulation of telomere maintenance via telomerase	1.373199e-5
GO:0006094	gluconeogenesis	1.381709e-5
GO:0051048	negative regulation of secretion	1.600786e-5
GO:0072668	tubulin complex biogenesis	1.695082e-5
GO:0051220	cytoplasmic sequestering of protein	1.707344e-5
GO:0090084	negative regulation of inclusion body assembly	1.780180e-5
GO:0018364	peptidyl-glutamine methylation	1.851281e-5
GO:0016191	synaptic vesicle uncoating	1.851281e-5
GO:0051345	positive regulation of hydrolase activity	1.903436e-5
GO:0050746	regulation of lipoprotein metabolic process	2.010565e-5
GO:0031440	regulation of mRNA 3'-end processing	2.129829e-5
GO:0010936	negative regulation of macrophage cytokine production	2.450308e-5
GO:0043691	reverse cholesterol transport	2.475515e-5
GO:0090086	negative regulation of protein deubiquitination	2.665340e-5
GO:0051081	nuclear envelope disassembly	2.748102e-5
GO:0045807	positive regulation of endocytosis	2.834089e-5
GO:0010466	negative regulation of peptidase activity	2.848762e-5
GO:0016081	synaptic vesicle docking involved in exocytosis	3.072561e-5
GO:0050434	positive regulation of viral transcription	3.092647e-5
GO:0046477	glycosylceramide catabolic process	3.240635e-5
GO:0033124	regulation of GTP catabolic process	3.286393e-5
GO:0010872	regulation of cholesterol esterification	3.435423e-5
GO:0043087	regulation of GTPase activity	3.532807e-5
GO:0010312	detoxification of zinc ion	3.810149e-5
GO:0045925	positive regulation of female receptivity	3.922218e-5
GO:0035674	tricarboxylic acid transmembrane transport	4.130779e-5
GO:0007565	female pregnancy	4.345104e-5
GO:0030100	regulation of endocytosis	4.480192e-5
GO:0006298	mismatch repair	4.627216e-5
GO:0006756	AMP phosphorylation	4.731972e-5
GO:0032320	positive regulation of Ras GTPase activity	5.028497e-5
GO:0032007	negative regulation of TOR signaling cascade	5.872902e-5
GO:0009201	ribonucleoside triphosphate biosynthetic process	5.936608e-5
GO:0042482	positive regulation of odontogenesis	6.277712e-5
GO:0031109	microtubule polymerization or depolymerization	6.300741e-5
GO:0001845	phagolysosome assembly	6.545072e-5
GO:0010831	positive regulation of myotube differentiation	6.848357e-5
GO:0048242	epinephrine secretion	6.949021e-5
GO:0006754	ATP biosynthetic process	7.230596e-5
GO:0019430	removal of superoxide radicals	7.721152e-5
GO:0001754	eye photoreceptor cell differentiation	7.812165e-5
GO:0016064	immunoglobulin mediated immune response	7.897676e-5
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	8.120498e-5
GO:0032856	activation of Ras GTPase activity	8.153406e-5
GO:0046839	phospholipid dephosphorylation	8.264729e-5
GO:0051346	negative regulation of hydrolase activity	8.509484e-5
GO:0016125	sterol metabolic process	8.562914e-5
GO:0019724	B cell mediated immunity	8.856812e-5
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	8.882149e-5
GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	9.199066e-5
GO:0009817	defense response to fungus, incompatible interaction	9.199066e-5
GO:0097107	postsynaptic density assembly	9.199066e-5
GO:0060561	apoptosis involved in morphogenesis	9.550357e-5
GO:0007131	reciprocal meiotic recombination	1.006131e-4
GO:0009142	nucleoside triphosphate biosynthetic process	1.009656e-4
GO:0032232	negative regulation of actin filament bundle assembly	1.009676e-4
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	1.136045e-4
GO:0035928	rRNA import into mitochondrion	1.136045e-4
GO:0002426	immunoglobulin production in mucosal tissue	1.150034e-4
GO:0006448	regulation of translational elongation	1.150034e-4
GO:0008594	photoreceptor cell morphogenesis	1.202934e-4
GO:0021592	fourth ventricle development	1.209682e-4
GO:2000378	negative regulation of reactive oxygen species metabolic process	1.216805e-4
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	1.220407e-4
GO:2000178	negative regulation of neural precursor cell proliferation	1.246398e-4
GO:0051261	protein depolymerization	1.255601e-4
GO:0034763	negative regulation of transmembrane transport	1.278914e-4
GO:0042306	regulation of protein import into nucleus	1.315899e-4
GO:0003266	regulation of secondary heart field cardioblast proliferation	1.372003e-4
GO:0072200	negative regulation of mesenchymal cell proliferation involved in ureter development	1.428286e-4
GO:0072198	mesenchymal cell proliferation involved in ureter development	1.428286e-4
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	1.428286e-4
GO:0072138	mesenchymal cell proliferation involved in ureteric bud development	1.428286e-4
GO:0072192	ureter epithelial cell differentiation	1.428286e-4
GO:2000007	negative regulation of metanephric comma-shaped body morphogenesis	1.428286e-4
GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis	1.428286e-4
GO:0072101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	1.428286e-4
GO:2000005	negative regulation of metanephric S-shaped body morphogenesis	1.428286e-4
GO:0090194	negative regulation of glomerulus development	1.428286e-4
GO:0055020	positive regulation of cardiac muscle fiber development	1.428286e-4
GO:0072097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	1.428286e-4
GO:0048392	intermediate mesodermal cell differentiation	1.428286e-4
GO:0007500	mesodermal cell fate determination	1.428286e-4
GO:0060503	bud dilation involved in lung branching	1.428286e-4
GO:0060502	epithelial cell proliferation involved in lung morphogenesis	1.428286e-4
GO:0071893	BMP signaling pathway involved in nephric duct formation	1.428286e-4
GO:0061155	pulmonary artery endothelial tube morphogenesis	1.428286e-4
GO:0061151	BMP signaling pathway involved in renal system segmentation	1.428286e-4
GO:0061149	BMP signaling pathway involved in ureter morphogenesis	1.428286e-4
GO:0034103	regulation of tissue remodeling	1.460003e-4
GO:0090207	regulation of triglyceride metabolic process	1.463181e-4
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.512761e-4
GO:0034614	cellular response to reactive oxygen species	1.597643e-4
GO:0051412	response to corticosterone stimulus	1.623517e-4
GO:0000303	response to superoxide	1.761139e-4
GO:0051224	negative regulation of protein transport	1.821641e-4
GO:0097035	regulation of membrane lipid distribution	1.827962e-4
GO:0006403	RNA localization	1.837178e-4
GO:0042461	photoreceptor cell development	1.839869e-4
GO:0002252	immune effector process	1.889918e-4
GO:0042694	muscle cell fate specification	1.941558e-4
GO:0035990	tendon cell differentiation	1.945376e-4
GO:0080111	DNA demethylation	1.965835e-4
GO:0002443	leukocyte mediated immunity	1.972211e-4
GO:0045843	negative regulation of striated muscle tissue development	2.182706e-4
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	2.192691e-4
GO:0042135	neurotransmitter catabolic process	2.194029e-4
GO:0009145	purine nucleoside triphosphate biosynthetic process	2.194330e-4
GO:0023021	termination of signal transduction	2.261233e-4
GO:0043401	steroid hormone mediated signaling pathway	2.343944e-4
GO:0050996	positive regulation of lipid catabolic process	2.367556e-4
GO:0002885	positive regulation of hypersensitivity	2.402132e-4
GO:0001778	plasma membrane repair	2.412077e-4
GO:0044243	multicellular organismal catabolic process	2.519542e-4
GO:0000045	autophagic vacuole assembly	2.519542e-4
GO:0070328	triglyceride homeostasis	2.530546e-4
GO:0032984	macromolecular complex disassembly	2.530546e-4
GO:0019319	hexose biosynthetic process	2.540063e-4
GO:0002238	response to molecule of fungal origin	2.581668e-4
GO:0010830	regulation of myotube differentiation	2.601682e-4
GO:0006012	galactose metabolic process	2.633941e-4
GO:0008203	cholesterol metabolic process	2.666610e-4
GO:0048742	regulation of skeletal muscle fiber development	2.747457e-4
GO:0006419	alanyl-tRNA aminoacylation	2.869637e-4
GO:0003130	BMP signaling pathway involved in heart induction	2.869637e-4
GO:0090076	relaxation of skeletal muscle	2.923875e-4
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	2.923875e-4
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.992977e-4
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	3.038640e-4
GO:0016322	neuron remodeling	3.042457e-4
GO:0007341	penetration of zona pellucida	3.047716e-4
GO:0015931	nucleobase-containing compound transport	3.060623e-4
GO:0002756	MyD88-independent toll-like receptor signaling pathway	3.110841e-4
GO:0001579	medium-chain fatty acid transport	3.110841e-4
GO:0033121	regulation of purine nucleotide catabolic process	3.112648e-4
GO:0051532	regulation of NFAT protein import into nucleus	3.218988e-4
GO:0072095	regulation of branch elongation involved in ureteric bud branching	3.221319e-4
GO:0000395	nuclear mRNA 5'-splice site recognition	3.241278e-4
GO:0006406	mRNA export from nucleus	3.266650e-4
GO:0045655	regulation of monocyte differentiation	3.276432e-4
GO:0032488	Cdc42 protein signal transduction	3.276432e-4
GO:0032375	negative regulation of cholesterol transport	3.330423e-4
GO:0052548	regulation of endopeptidase activity	3.438605e-4
GO:0009583	detection of light stimulus	3.504999e-4
GO:0007221	positive regulation of transcription of Notch receptor target	3.511345e-4
GO:0002636	positive regulation of germinal center formation	3.511345e-4
GO:2000117	negative regulation of cysteine-type endopeptidase activity	3.544160e-4
GO:0051176	positive regulation of sulfur metabolic process	3.544160e-4
GO:0050926	regulation of positive chemotaxis	3.590293e-4
GO:0050663	cytokine secretion	3.648169e-4
GO:0021678	third ventricle development	3.648262e-4
GO:0045657	positive regulation of monocyte differentiation	3.648262e-4
GO:0072273	metanephric nephron morphogenesis	3.755705e-4
GO:0042339	keratan sulfate metabolic process	3.779122e-4
GO:0046823	negative regulation of nucleocytoplasmic transport	3.871763e-4
GO:0042424	catecholamine catabolic process	3.990625e-4
GO:0048635	negative regulation of muscle organ development	4.017628e-4
GO:0016576	histone dephosphorylation	4.068895e-4
GO:0035993	deltoid tuberosity development	4.141990e-4
GO:0002920	regulation of humoral immune response	4.469853e-4
GO:0006207	'de novo' pyrimidine base biosynthetic process	4.567946e-4
GO:0006984	ER-nucleus signaling pathway	4.726278e-4
GO:0006405	RNA export from nucleus	4.738020e-4
GO:0042304	regulation of fatty acid biosynthetic process	4.922739e-4
GO:0045723	positive regulation of fatty acid biosynthetic process	5.056548e-4
GO:0019637	organophosphate metabolic process	5.136356e-4
GO:0045619	regulation of lymphocyte differentiation	5.395416e-4
GO:0065005	protein-lipid complex assembly	5.564553e-4
GO:0002275	myeloid cell activation involved in immune response	5.634366e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	5.696504e-4
GO:0050658	RNA transport	5.707570e-4
GO:0009755	hormone-mediated signaling pathway	5.838271e-4
GO:0001555	oocyte growth	5.893737e-4
GO:0035510	DNA dealkylation	6.150140e-4
GO:0006213	pyrimidine nucleoside metabolic process	6.259094e-4
GO:0045601	regulation of endothelial cell differentiation	6.315155e-4
GO:0035023	regulation of Rho protein signal transduction	6.338410e-4
GO:0044092	negative regulation of molecular function	6.426016e-4
GO:0043932	ossification involved in bone remodeling	6.490235e-4
GO:0006883	cellular sodium ion homeostasis	6.490235e-4
GO:0060591	chondroblast differentiation	6.497935e-4
GO:0051026	chiasma assembly	6.497935e-4
GO:0045113	regulation of integrin biosynthetic process	6.940799e-4
GO:0051639	actin filament network formation	6.940799e-4
GO:0032571	response to vitamin K	6.940799e-4
GO:0045618	positive regulation of keratinocyte differentiation	6.987890e-4
GO:0090208	positive regulation of triglyceride metabolic process	7.062909e-4
GO:0045621	positive regulation of lymphocyte differentiation	7.098728e-4
GO:0051096	positive regulation of helicase activity	7.195264e-4
GO:0060010	Sertoli cell fate commitment	7.257113e-4
GO:0043241	protein complex disassembly	7.298009e-4
GO:0006543	glutamine catabolic process	7.328433e-4
GO:0070375	BMK cascade	7.366144e-4
GO:0009586	rhodopsin mediated phototransduction	7.366144e-4
GO:0032231	regulation of actin filament bundle assembly	7.501413e-4
GO:0051126	negative regulation of actin nucleation	7.618255e-4
GO:0010954	positive regulation of protein processing	7.755749e-4
GO:0046364	monosaccharide biosynthetic process	7.827059e-4
GO:0006909	phagocytosis	7.838776e-4
GO:0009912	auditory receptor cell fate commitment	7.849607e-4
GO:0045661	regulation of myoblast differentiation	7.931734e-4
GO:0051385	response to mineralocorticoid stimulus	8.010086e-4
GO:0002449	lymphocyte mediated immunity	8.042388e-4
GO:0001935	endothelial cell proliferation	8.206451e-4
GO:0045408	regulation of interleukin-6 biosynthetic process	8.273528e-4
GO:0034976	response to endoplasmic reticulum stress	8.421355e-4
GO:0007266	Rho protein signal transduction	8.517317e-4
GO:0060381	positive regulation of single-stranded telomeric DNA binding	8.536718e-4
GO:0035865	cellular response to potassium ion	8.536718e-4
GO:0034651	cortisol biosynthetic process	8.536718e-4
GO:0022400	regulation of rhodopsin mediated signaling pathway	8.536718e-4
GO:0034623	cellular macromolecular complex disassembly	9.010666e-4
GO:0050432	catecholamine secretion	9.042866e-4
GO:0031442	positive regulation of mRNA 3'-end processing	9.042866e-4
GO:0071422	succinate transmembrane transport	9.192263e-4
GO:0006694	steroid biosynthetic process	9.268913e-4
GO:0001798	positive regulation of type IIa hypersensitivity	9.276166e-4
GO:0051051	negative regulation of transport	9.282843e-4
GO:0051028	mRNA transport	9.465188e-4
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	9.522472e-4
GO:0032331	negative regulation of chondrocyte differentiation	9.848740e-4
GO:0002526	acute inflammatory response	1.012055e-3
GO:2000116	regulation of cysteine-type endopeptidase activity	1.012641e-3
GO:0050927	positive regulation of positive chemotaxis	1.036019e-3
GO:0034637	cellular carbohydrate biosynthetic process	1.044603e-3
GO:0006290	pyrimidine dimer repair	1.050904e-3
GO:0014015	positive regulation of gliogenesis	1.053431e-3
GO:0043623	cellular protein complex assembly	1.053561e-3
GO:0042462	eye photoreceptor cell development	1.054694e-3
GO:0060457	negative regulation of digestive system process	1.073098e-3
GO:0043586	tongue development	1.104356e-3
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.118738e-3
GO:0014874	response to stimulus involved in regulation of muscle adaptation	1.118738e-3
GO:2000974	negative regulation of pro-B cell differentiation	1.136077e-3
GO:0006868	glutamine transport	1.136077e-3
GO:0045579	positive regulation of B cell differentiation	1.163635e-3
GO:0071956	cellular component maintenance at cellular level	1.178554e-3
GO:0030263	apoptotic chromosome condensation	1.192951e-3
GO:0048554	positive regulation of metalloenzyme activity	1.208022e-3
GO:0090317	negative regulation of intracellular protein transport	1.242883e-3
GO:0031100	organ regeneration	1.266937e-3
GO:0051497	negative regulation of stress fiber assembly	1.273866e-3
GO:0060427	lung connective tissue development	1.280597e-3
GO:0006680	glucosylceramide catabolic process	1.280597e-3
GO:0045332	phospholipid translocation	1.299072e-3
GO:0042420	dopamine catabolic process	1.299072e-3
GO:0042542	response to hydrogen peroxide	1.330076e-3
GO:0021993	initiation of neural tube closure	1.336088e-3
GO:0030719	P granule organization	1.339427e-3
GO:0045830	positive regulation of isotype switching	1.340732e-3
GO:0060161	positive regulation of dopamine receptor signaling pathway	1.373408e-3
GO:0032425	positive regulation of mismatch repair	1.373408e-3
GO:0031329	regulation of cellular catabolic process	1.374712e-3
GO:0035552	oxidative single-stranded DNA demethylation	1.382524e-3
GO:0032277	negative regulation of gonadotropin secretion	1.382524e-3
GO:0061154	endothelial tube morphogenesis	1.386530e-3
GO:0061047	positive regulation of branching involved in lung morphogenesis	1.386530e-3
GO:0051168	nuclear export	1.388648e-3
GO:0050921	positive regulation of chemotaxis	1.390787e-3
GO:0006446	regulation of translational initiation	1.402954e-3
GO:0009065	glutamine family amino acid catabolic process	1.495472e-3
GO:0007265	Ras protein signal transduction	1.510236e-3
GO:0030178	negative regulation of Wnt receptor signaling pathway	1.525222e-3
GO:0061311	cell surface receptor linked signaling pathway involved in heart development	1.591284e-3
GO:0032103	positive regulation of response to external stimulus	1.606318e-3
GO:0032471	reduction of endoplasmic reticulum calcium ion concentration	1.613625e-3
GO:0051642	centrosome localization	1.614114e-3
GO:0034104	negative regulation of tissue remodeling	1.626261e-3
GO:0070212	protein poly-ADP-ribosylation	1.627103e-3
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.627103e-3
GO:0032212	positive regulation of telomere maintenance via telomerase	1.627103e-3
GO:0038027	apolipoprotein A-I-mediated signaling pathway	1.627103e-3
GO:0045217	cell-cell junction maintenance	1.648597e-3
GO:0032367	intracellular cholesterol transport	1.648597e-3
GO:0007405	neuroblast proliferation	1.658920e-3
GO:0014819	regulation of skeletal muscle contraction	1.725233e-3
GO:0021670	lateral ventricle development	1.769126e-3
GO:0048593	camera-type eye morphogenesis	1.772080e-3
GO:0045409	negative regulation of interleukin-6 biosynthetic process	1.773155e-3
GO:0045143	homologous chromosome segregation	1.773155e-3
GO:0070301	cellular response to hydrogen peroxide	1.839522e-3
GO:0006538	glutamate catabolic process	1.853274e-3
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	1.853274e-3
GO:0051095	regulation of helicase activity	1.853274e-3
GO:0046850	regulation of bone remodeling	1.860304e-3
GO:0018298	protein-chromophore linkage	1.887257e-3
GO:0046967	cytosol to ER transport	1.892880e-3
GO:0060611	mammary gland fat development	1.892880e-3
GO:0019060	intracellular transport of viral proteins in host cell	1.892880e-3
GO:0010918	positive regulation of mitochondrial membrane potential	1.892880e-3
GO:0031424	keratinization	1.923739e-3
GO:0003407	neural retina development	1.927903e-3
GO:0051223	regulation of protein transport	1.954971e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	1.956893e-3
GO:0050871	positive regulation of B cell activation	2.028430e-3
GO:0035725	sodium ion transmembrane transport	2.036893e-3
GO:0007256	activation of JNKK activity	2.053451e-3
GO:0045603	positive regulation of endothelial cell differentiation	2.072470e-3
GO:0072124	regulation of glomerular mesangial cell proliferation	2.080787e-3
GO:0016126	sterol biosynthetic process	2.126416e-3
GO:0006370	mRNA capping	2.161507e-3
GO:0035304	regulation of protein dephosphorylation	2.185305e-3
GO:0007173	epidermal growth factor receptor signaling pathway	2.216487e-3
GO:0016578	histone deubiquitination	2.230819e-3
GO:2000377	regulation of reactive oxygen species metabolic process	2.320231e-3
GO:0002250	adaptive immune response	2.324745e-3
GO:0048592	eye morphogenesis	2.338629e-3
GO:0045872	positive regulation of rhodopsin gene expression	2.342597e-3
GO:0001682	tRNA 5'-leader removal	2.342597e-3
GO:0043252	sodium-independent organic anion transport	2.342597e-3
GO:0035048	splicing factor protein import into nucleus	2.342597e-3
GO:0016078	tRNA catabolic process	2.342597e-3
GO:0021528	commissural neuron differentiation in spinal cord	2.342597e-3
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	2.348828e-3
GO:0072539	T-helper 17 cell differentiation	2.376093e-3
GO:0002536	respiratory burst involved in inflammatory response	2.376093e-3
GO:0030903	notochord development	2.413537e-3
GO:0007184	SMAD protein import into nucleus	2.413537e-3
GO:0006882	cellular zinc ion homeostasis	2.431822e-3
GO:0071599	otic vesicle development	2.439926e-3
GO:0042274	ribosomal small subunit biogenesis	2.477396e-3
GO:0032211	negative regulation of telomere maintenance via telomerase	2.486330e-3
GO:0015886	heme transport	2.486330e-3
GO:0009299	mRNA transcription	2.486330e-3
GO:0030046	parallel actin filament bundle assembly	2.493892e-3
GO:0002513	tolerance induction to self antigen	2.493892e-3
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	2.515911e-3
GO:0045218	zonula adherens maintenance	2.539261e-3
GO:0050917	sensory perception of umami taste	2.539261e-3
GO:0070509	calcium ion import	2.545928e-3
GO:0045905	positive regulation of translational termination	2.558416e-3
GO:0006452	translational frameshifting	2.558416e-3
GO:0045901	positive regulation of translational elongation	2.558416e-3
GO:0007028	cytoplasm organization	2.572997e-3
GO:0050792	regulation of viral reproduction	2.599394e-3
GO:0016458	gene silencing	2.601859e-3
GO:0017145	stem cell division	2.635952e-3
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	2.641112e-3
GO:0007406	negative regulation of neuroblast proliferation	2.665527e-3
GO:0048599	oocyte development	2.687711e-3
GO:0072125	negative regulation of glomerular mesangial cell proliferation	2.695344e-3
GO:0046434	organophosphate catabolic process	2.695984e-3
GO:0043086	negative regulation of catalytic activity	2.734970e-3
GO:0000302	response to reactive oxygen species	2.750897e-3
GO:0001970	positive regulation of activation of membrane attack complex	2.777751e-3
GO:0061049	cell growth involved in cardiac muscle cell development	2.822652e-3
GO:0061302	smooth muscle cell-matrix adhesion	2.822652e-3
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	2.822652e-3
GO:0008065	establishment of blood-nerve barrier	2.822652e-3
GO:0003331	positive regulation of extracellular matrix constituent secretion	2.822652e-3
GO:0009450	gamma-aminobutyric acid catabolic process	2.822652e-3
GO:0045580	regulation of T cell differentiation	2.834302e-3
GO:0090257	regulation of muscle system process	2.853857e-3
GO:0009416	response to light stimulus	2.855913e-3
GO:0072050	S-shaped body morphogenesis	2.860541e-3
GO:0072049	comma-shaped body morphogenesis	2.860541e-3
GO:0070141	response to UV-A	2.861051e-3
GO:0045924	regulation of female receptivity	2.876241e-3
GO:0051029	rRNA transport	2.877911e-3
GO:0009620	response to fungus	2.886467e-3
GO:0010951	negative regulation of endopeptidase activity	3.032422e-3
GO:0032957	inositol trisphosphate metabolic process	3.113442e-3
GO:2000243	positive regulation of reproductive process	3.132532e-3
GO:0001658	branching involved in ureteric bud morphogenesis	3.135584e-3
GO:0021591	ventricular system development	3.171776e-3
GO:0043624	cellular protein complex disassembly	3.186334e-3
GO:0006105	succinate metabolic process	3.194016e-3
GO:0034330	cell junction organization	3.229458e-3
GO:0046131	pyrimidine ribonucleoside metabolic process	3.257044e-3
GO:0016032	viral reproduction	3.260345e-3
GO:0033194	response to hydroperoxide	3.298951e-3
GO:0022414	reproductive process	3.303133e-3
GO:0048641	regulation of skeletal muscle tissue development	3.331600e-3
GO:0000003	reproduction	3.341877e-3
GO:0032006	regulation of TOR signaling cascade	3.386759e-3
GO:0070670	response to interleukin-4	3.396106e-3
GO:0032318	regulation of Ras GTPase activity	3.404196e-3
GO:0010269	response to selenium ion	3.423676e-3
GO:0006955	immune response	3.437057e-3
GO:0060391	positive regulation of SMAD protein import into nucleus	3.453331e-3
GO:0070198	protein localization to chromosome, telomeric region	3.463464e-3
GO:0035511	oxidative DNA demethylation	3.463464e-3
GO:0002883	regulation of hypersensitivity	3.488577e-3
GO:0015938	coenzyme A catabolic process	3.555276e-3
GO:0010041	response to iron(III) ion	3.555276e-3
GO:0002897	positive regulation of central B cell tolerance induction	3.555276e-3
GO:0002508	central tolerance induction	3.555276e-3
GO:0009894	regulation of catabolic process	3.630225e-3
GO:0042036	negative regulation of cytokine biosynthetic process	3.653093e-3
GO:0033084	regulation of immature T cell proliferation in thymus	3.670678e-3
GO:0048754	branching morphogenesis of a tube	3.676900e-3
GO:0051788	response to misfolded protein	3.689848e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	3.732031e-3
GO:0000320	re-entry into mitotic cell cycle	3.753063e-3
GO:0045582	positive regulation of T cell differentiation	3.805174e-3
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	3.921007e-3
GO:0008340	determination of adult lifespan	3.924873e-3
GO:0071214	cellular response to abiotic stimulus	3.974188e-3
GO:0060113	inner ear receptor cell differentiation	3.997961e-3
GO:0070989	oxidative demethylation	4.039263e-3
GO:0060621	negative regulation of cholesterol import	4.039263e-3
GO:0000710	meiotic mismatch repair	4.039263e-3
GO:0007386	compartment pattern specification	4.039263e-3
GO:0009260	ribonucleotide biosynthetic process	4.057598e-3
GO:0055025	positive regulation of cardiac muscle tissue development	4.065486e-3
GO:0006401	RNA catabolic process	4.076861e-3
GO:0010876	lipid localization	4.079250e-3
GO:0010625	positive regulation of Schwann cell proliferation	4.086318e-3
GO:0010273	detoxification of copper ion	4.086318e-3
GO:0048251	elastic fiber assembly	4.110069e-3
GO:0002701	negative regulation of production of molecular mediator of immune response	4.110069e-3
GO:0060644	mammary gland epithelial cell differentiation	4.143768e-3
GO:0010212	response to ionizing radiation	4.146352e-3
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	4.173831e-3
GO:0046856	phosphatidylinositol dephosphorylation	4.222339e-3
GO:0033233	regulation of protein sumoylation	4.222339e-3
GO:0006071	glycerol metabolic process	4.249506e-3
GO:0005989	lactose biosynthetic process	4.253558e-3
GO:0003158	endothelium development	4.288272e-3
GO:0060440	trachea formation	4.298937e-3
GO:0010159	specification of organ position	4.334697e-3
GO:0060219	camera-type eye photoreceptor cell differentiation	4.342460e-3
GO:0002889	regulation of immunoglobulin mediated immune response	4.365080e-3
GO:0060627	regulation of vesicle-mediated transport	4.397910e-3
GO:0042490	mechanoreceptor differentiation	4.412782e-3
GO:0051156	glucose 6-phosphate metabolic process	4.425550e-3
GO:0006867	asparagine transport	4.425550e-3
GO:0006449	regulation of translational termination	4.425550e-3
GO:0021539	subthalamus development	4.440319e-3
GO:0046782	regulation of viral transcription	4.490004e-3
GO:0003219	cardiac right ventricle formation	4.491004e-3
GO:0032147	activation of protein kinase activity	4.508141e-3
GO:0042133	neurotransmitter metabolic process	4.538419e-3
GO:0007412	axon target recognition	4.572929e-3
GO:0003051	angiotensin-mediated drinking behavior	4.572929e-3
GO:0042439	ethanolamine-containing compound metabolic process	4.581250e-3
GO:2000173	negative regulation of branching morphogenesis of a nerve	4.648894e-3
GO:0070213	protein auto-ADP-ribosylation	4.648894e-3