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Coexpression cluster:C3671: Difference between revisions

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}}
}}

Revision as of 16:16, 26 November 2012


Full id: C3671_Neural_Chondrocyte_hepatocellular_caudate_signet_hippocampus_papillotubular



Phase1 CAGE Peaks

Hg19::chr17:70117153..70117174,+p1@SOX9
Hg19::chr17:70120097..70120118,+p@chr17:70120097..70120118
+
Hg19::chr17:70120252..70120370,-p@chr17:70120252..70120370
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
ectoderm-derived structure3.00e-32171
ectoderm3.00e-32171
presumptive ectoderm3.00e-32171
neural plate5.87e-3082
presumptive neural plate5.87e-3082
neural tube2.26e-2956
neural rod2.26e-2956
future spinal cord2.26e-2956
neural keel2.26e-2956
central nervous system3.75e-2981
ecto-epithelium1.43e-28104
neurectoderm2.09e-2886
anatomical cluster3.00e-28373
regional part of nervous system1.91e-2753
regional part of brain1.91e-2753
organ system subdivision3.98e-27223
nervous system1.39e-2689
multi-tissue structure1.92e-26342
brain2.62e-2668
future brain2.62e-2668
structure with developmental contribution from neural crest4.70e-26132
pre-chordal neural plate4.99e-2261
regional part of forebrain1.41e-2141
forebrain1.41e-2141
anterior neural tube1.41e-2141
future forebrain1.41e-2141
telencephalon3.48e-2034
brain grey matter3.83e-2034
gray matter3.83e-2034
regional part of telencephalon4.33e-1932
cerebral hemisphere5.38e-1932
cell layer1.37e-18309
anatomical conduit1.88e-18240
epithelium2.60e-18306
adult organism2.00e-16114
organ7.91e-16503
tube8.33e-16192
cerebral cortex1.68e-1525
pallium1.68e-1525
multi-cellular organism1.02e-14656
organ part1.48e-14218
regional part of cerebral cortex6.47e-1422
anatomical system1.55e-13624
anatomical group2.62e-13625
embryo2.64e-13592
neocortex1.38e-1220
developing anatomical structure1.90e-11581
posterior neural tube6.55e-0915
chordal neural plate6.55e-0915
embryonic structure1.07e-08564
organism subdivision2.68e-08264
germ layer2.94e-08560
germ layer / neural crest2.94e-08560
embryonic tissue2.94e-08560
presumptive structure2.94e-08560
germ layer / neural crest derived structure2.94e-08560
epiblast (generic)2.94e-08560
compound organ1.03e-0768
segmental subdivision of hindbrain4.23e-0712
hindbrain4.23e-0712
presumptive hindbrain4.23e-0712
endoderm-derived structure4.87e-07160
endoderm4.87e-07160
presumptive endoderm4.87e-07160


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.