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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0354470656487682,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.798161532819708,0.696420098559158,0,0,0,0,0.052188704109448,0.164596587144155,0,0,0,0.321855166838861,0,0.0617533076901792,0.756944596266849,0.791893032815025,0.426689997816029,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0557624462303155,0.0825867363219064,0,0,0,0,0.113803446464706,0.163608743054207,0,0,0,0.150933218241173,0.0652962901395099,0,0,0,0,0,0,0,0,0,0,0.0388988969149198,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.786658507121516,0.792676246844224,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.01341358675313,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0435794416222198,0,0,0,0,0.0375226752578547,0.0388749848471105,0.0523284672130554,0.0581328665260699,0,0.0476191773904887,0.0766073954291401,0,0.0596387295197733,0.0640168649599105,0.0709519923534245,0,0.0589368614163519,0.0390607415003592,0.0678996586311492,0,0,0,0,0.0486884105045233,0.0594496181738161,0,0.0625582350728301,0,0.0484220980280083,0,0.0845301845292944,0.0760168881589905,0,0.0905641158318875
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0354470656487682,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.798161532819708,0.696420098559158,0,0,0,0,0.052188704109448,0.164596587144155,0,0,0,0.321855166838861,0,0.0617533076901792,0.756944596266849,0.791893032815025,0.426689997816029,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0557624462303155,0.0825867363219064,0,0,0,0,0.113803446464706,0.163608743054207,0,0,0,0.150933218241173,0.0652962901395099,0,0,0,0,0,0,0,0,0,0,0.0388988969149198,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.786658507121516,0.792676246844224,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.01341358675313,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0435794416222198,0,0,0,0,0.0375226752578547,0.0388749848471105,0.0523284672130554,0.0581328665260699,0,0.0476191773904887,0.0766073954291401,0,0.0596387295197733,0.0640168649599105,0.0709519923534245,0,0.0589368614163519,0.0390607415003592,0.0678996586311492,0,0,0,0,0.0486884105045233,0.0594496181738161,0,0.0625582350728301,0,0.0484220980280083,0,0.0845301845292944,0.0760168881589905,0,0.0905641158318875
|gostat_on_MCL_coexpression=GO:0005275;amine transmembrane transporter activity;1.94117445984349e-05;63993,20508,20538!GO:0008504;monoamine transmembrane transporter activity;4.45609887683677e-05;20508,20538!GO:0015370;solute:sodium symporter activity;0.00290317603935904;63993,20538!GO:0022804;active transmembrane transporter activity;0.00290317603935904;63993,20508,20538!GO:0006836;neurotransmitter transport;0.00290317603935904;20508,20538!GO:0015294;solute:cation symporter activity;0.00290317603935904;63993,20538!GO:0015837;amine transport;0.00290317603935904;63993,20538!GO:0008292;acetylcholine biosynthetic process;0.00602640661809018;63993!GO:0005307;choline:sodium symporter activity;0.00602640661809018;63993!GO:0008291;acetylcholine metabolic process;0.00903837176009507;63993!GO:0015871;choline transport;0.00903837176009507;63993!GO:0015220;choline transmembrane transporter activity;0.00903837176009507;63993!GO:0015293;symporter activity;0.00984208619353216;63993,20538!GO:0031133;regulation of axon diameter;0.0101667754957099;18040!GO:0045110;intermediate filament bundle assembly;0.0101667754957099;18040!GO:0015844;monoamine transport;0.0101667754957099;20538!GO:0042439;ethanolamine and derivative metabolic process;0.0123921007879047;63993!GO:0015291;secondary active transmembrane transporter activity;0.0123921007879047;63993,20538!GO:0022857;transmembrane transporter activity;0.014520768102974;63993,20508,20538!GO:0043195;terminal button;0.0154858644013815;20508!GO:0005883;neurofilament;0.0154858644013815;18040!GO:0006810;transport;0.0187540123604468;18040,63993,20508,20538!GO:0060053;neurofilament cytoskeleton;0.0187540123604468;18040!GO:0060052;neurofilament cytoskeleton organization and biogenesis;0.0187540123604468;18040!GO:0045109;intermediate filament organization;0.0187540123604468;18040!GO:0033267;axon part;0.0187540123604468;20508!GO:0051234;establishment of localization;0.0192789108118965;18040,63993,20508,20538!GO:0008088;axon cargo transport;0.019346727717088;18040!GO:0042176;regulation of protein catabolic process;0.020112330883035;282663!GO:0048265;response to pain;0.020112330883035;20538!GO:0031594;neuromuscular junction;0.020112330883035;18040!GO:0007274;neuromuscular synaptic transmission;0.020112330883035;63993!GO:0009894;regulation of catabolic process;0.020112330883035;282663!GO:0042136;neurotransmitter biosynthetic process;0.020112330883035;63993!GO:0007271;synaptic transmission, cholinergic;0.020112330883035;63993!GO:0051179;localization;0.0228123038652274;18040,63993,20508,20538!GO:0045104;intermediate filament cytoskeleton organization and biogenesis;0.0248654523517968;18040!GO:0005328;neurotransmitter:sodium symporter activity;0.0256317698159375;20538!GO:0045103;intermediate filament-based process;0.0270483470018585;18040!GO:0005326;neurotransmitter transporter activity;0.0270483470018585;20538!GO:0042401;biogenic amine biosynthetic process;0.0316490147677722;63993!GO:0033555;multicellular organismal response to stress;0.0321783707287936;20538!GO:0008324;cation transmembrane transporter activity;0.0335335216595175;63993,20538!GO:0042398;amino acid derivative biosynthetic process;0.0343874727040846;63993!GO:0050770;regulation of axonogenesis;0.0360151058030516;18040!GO:0004601;peroxidase activity;0.0379152230653866;282663!GO:0016684;oxidoreductase activity, acting on peroxide as acceptor;0.0379152230653866;282663!GO:0042133;neurotransmitter metabolic process;0.0416025674897824;63993!GO:0050767;regulation of neurogenesis;0.0495108445735055;18040!
|gostat_on_MCL_coexpression=GO:0005275;amine transmembrane transporter activity;1.94117445984349e-05;63993,20508,20538!GO:0008504;monoamine transmembrane transporter activity;4.45609887683677e-05;20508,20538!GO:0015370;solute:sodium symporter activity;0.00290317603935904;63993,20538!GO:0022804;active transmembrane transporter activity;0.00290317603935904;63993,20508,20538!GO:0006836;neurotransmitter transport;0.00290317603935904;20508,20538!GO:0015294;solute:cation symporter activity;0.00290317603935904;63993,20538!GO:0015837;amine transport;0.00290317603935904;63993,20538!GO:0008292;acetylcholine biosynthetic process;0.00602640661809018;63993!GO:0005307;choline:sodium symporter activity;0.00602640661809018;63993!GO:0008291;acetylcholine metabolic process;0.00903837176009507;63993!GO:0015871;choline transport;0.00903837176009507;63993!GO:0015220;choline transmembrane transporter activity;0.00903837176009507;63993!GO:0015293;symporter activity;0.00984208619353216;63993,20538!GO:0031133;regulation of axon diameter;0.0101667754957099;18040!GO:0045110;intermediate filament bundle assembly;0.0101667754957099;18040!GO:0015844;monoamine transport;0.0101667754957099;20538!GO:0042439;ethanolamine and derivative metabolic process;0.0123921007879047;63993!GO:0015291;secondary active transmembrane transporter activity;0.0123921007879047;63993,20538!GO:0022857;transmembrane transporter activity;0.014520768102974;63993,20508,20538!GO:0043195;terminal button;0.0154858644013815;20508!GO:0005883;neurofilament;0.0154858644013815;18040!GO:0006810;transport;0.0187540123604468;18040,63993,20508,20538!GO:0060053;neurofilament cytoskeleton;0.0187540123604468;18040!GO:0060052;neurofilament cytoskeleton organization and biogenesis;0.0187540123604468;18040!GO:0045109;intermediate filament organization;0.0187540123604468;18040!GO:0033267;axon part;0.0187540123604468;20508!GO:0051234;establishment of localization;0.0192789108118965;18040,63993,20508,20538!GO:0008088;axon cargo transport;0.019346727717088;18040!GO:0042176;regulation of protein catabolic process;0.020112330883035;282663!GO:0048265;response to pain;0.020112330883035;20538!GO:0031594;neuromuscular junction;0.020112330883035;18040!GO:0007274;neuromuscular synaptic transmission;0.020112330883035;63993!GO:0009894;regulation of catabolic process;0.020112330883035;282663!GO:0042136;neurotransmitter biosynthetic process;0.020112330883035;63993!GO:0007271;synaptic transmission, cholinergic;0.020112330883035;63993!GO:0051179;localization;0.0228123038652274;18040,63993,20508,20538!GO:0045104;intermediate filament cytoskeleton organization and biogenesis;0.0248654523517968;18040!GO:0005328;neurotransmitter:sodium symporter activity;0.0256317698159375;20538!GO:0045103;intermediate filament-based process;0.0270483470018585;18040!GO:0005326;neurotransmitter transporter activity;0.0270483470018585;20538!GO:0042401;biogenic amine biosynthetic process;0.0316490147677722;63993!GO:0033555;multicellular organismal response to stress;0.0321783707287936;20538!GO:0008324;cation transmembrane transporter activity;0.0335335216595175;63993,20538!GO:0042398;amino acid derivative biosynthetic process;0.0343874727040846;63993!GO:0050770;regulation of axonogenesis;0.0360151058030516;18040!GO:0004601;peroxidase activity;0.0379152230653866;282663!GO:0016684;oxidoreductase activity, acting on peroxide as acceptor;0.0379152230653866;282663!GO:0042133;neurotransmitter metabolic process;0.0416025674897824;63993!GO:0050767;regulation of neurogenesis;0.0495108445735055;18040!
|ontology_enrichment_celltype=CL:0002612!1.51e-08!3;CL:0000117!3.15e-07!23;CL:0000337!3.15e-07!23
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0003076!7.37e-20!12;UBERON:0003057!7.37e-20!12;UBERON:0002240!1.15e-15!6;UBERON:0005174!1.15e-15!6;UBERON:0001137!1.15e-15!6;UBERON:0001948!3.10e-13!5;UBERON:0002315!3.10e-13!5;UBERON:0000073!2.49e-09!54;UBERON:0001049!1.06e-08!52;UBERON:0005068!1.06e-08!52;UBERON:0006241!1.06e-08!52;UBERON:0007135!1.06e-08!52;UBERON:0002257!1.51e-08!3;UBERON:0002346!2.88e-07!64;UBERON:0003075!2.88e-07!64;UBERON:0007284!2.88e-07!64;UBERON:0001017!7.37e-07!73;UBERON:0004733!9.41e-07!6;UBERON:0004732!9.41e-07!6;UBERON:0002028!9.41e-07!6;UBERON:0007277!9.41e-07!6
}}
}}

Revision as of 20:13, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:118431001..118431046,-p4@Rbfox3
Mm9::chr11:118431276..118431314,-p3@Rbfox3
Mm9::chr11:118431626..118431637,-p16@Rbfox3
Mm9::chr13:33175964..33175973,+p2@Serpinb1b
Mm9::chr13:33175982..33176015,+p1@Serpinb1b
Mm9::chr14:33277893..33277902,-p6@Slc18a3
Mm9::chr14:33277950..33277963,-p1@Slc18a3
Mm9::chr14:68742893..68742913,-p1@Nefm
Mm9::chr17:54438043..54438057,-p1@Slc5a7
Mm9::chr2:70053872..70053879,+p@chr2:70053872..70053879
+
Mm9::chr4:137573229..137573260,+p@chr4:137573229..137573260
+
Mm9::chr4:137573261..137573269,+p@chr4:137573261..137573269
+
Mm9::chr4:150371190..150371197,+p1@Uts2
Mm9::chr7:57165440..57165441,+p13@Slc6a5
Mm9::chr7:57165453..57165473,+p3@Slc6a5
Mm9::chr7:57165482..57165497,+p2@Slc6a5
Mm9::chr7:57165576..57165593,+p5@Slc6a5
Mm9::chr7:57165602..57165612,+p6@Slc6a5
Mm9::chr7:57165629..57165651,+p4@Slc6a5
Mm9::chr7:57167425..57167443,+p@chr7:57167425..57167443
+
Mm9::chr7:57215165..57215169,+p@chr7:57215165..57215169
+
Mm9::chr7:57215305..57215314,+p@chr7:57215305..57215314
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005275amine transmembrane transporter activity1.94117445984349e-05
GO:0008504monoamine transmembrane transporter activity4.45609887683677e-05
GO:0015370solute:sodium symporter activity0.00290317603935904
GO:0022804active transmembrane transporter activity0.00290317603935904
GO:0006836neurotransmitter transport0.00290317603935904
GO:0015294solute:cation symporter activity0.00290317603935904
GO:0015837amine transport0.00290317603935904
GO:0008292acetylcholine biosynthetic process0.00602640661809018
GO:0005307choline:sodium symporter activity0.00602640661809018
GO:0008291acetylcholine metabolic process0.00903837176009507
GO:0015871choline transport0.00903837176009507
GO:0015220choline transmembrane transporter activity0.00903837176009507
GO:0015293symporter activity0.00984208619353216
GO:0031133regulation of axon diameter0.0101667754957099
GO:0045110intermediate filament bundle assembly0.0101667754957099
GO:0015844monoamine transport0.0101667754957099
GO:0042439ethanolamine and derivative metabolic process0.0123921007879047
GO:0015291secondary active transmembrane transporter activity0.0123921007879047
GO:0022857transmembrane transporter activity0.014520768102974
GO:0043195terminal button0.0154858644013815
GO:0005883neurofilament0.0154858644013815
GO:0006810transport0.0187540123604468
GO:0060053neurofilament cytoskeleton0.0187540123604468
GO:0060052neurofilament cytoskeleton organization and biogenesis0.0187540123604468
GO:0045109intermediate filament organization0.0187540123604468
GO:0033267axon part0.0187540123604468
GO:0051234establishment of localization0.0192789108118965
GO:0008088axon cargo transport0.019346727717088
GO:0042176regulation of protein catabolic process0.020112330883035
GO:0048265response to pain0.020112330883035
GO:0031594neuromuscular junction0.020112330883035
GO:0007274neuromuscular synaptic transmission0.020112330883035
GO:0009894regulation of catabolic process0.020112330883035
GO:0042136neurotransmitter biosynthetic process0.020112330883035
GO:0007271synaptic transmission, cholinergic0.020112330883035
GO:0051179localization0.0228123038652274
GO:0045104intermediate filament cytoskeleton organization and biogenesis0.0248654523517968
GO:0005328neurotransmitter:sodium symporter activity0.0256317698159375
GO:0045103intermediate filament-based process0.0270483470018585
GO:0005326neurotransmitter transporter activity0.0270483470018585
GO:0042401biogenic amine biosynthetic process0.0316490147677722
GO:0033555multicellular organismal response to stress0.0321783707287936
GO:0008324cation transmembrane transporter activity0.0335335216595175
GO:0042398amino acid derivative biosynthetic process0.0343874727040846
GO:0050770regulation of axonogenesis0.0360151058030516
GO:0004601peroxidase activity0.0379152230653866
GO:0016684oxidoreductase activity, acting on peroxide as acceptor0.0379152230653866
GO:0042133neurotransmitter metabolic process0.0416025674897824
GO:0050767regulation of neurogenesis0.0495108445735055



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuron of the ventral spinal cord1.51e-083
CNS neuron (sensu Vertebrata)3.15e-0723
neuroblast (sensu Vertebrata)3.15e-0723


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}