MCL coexpression mm9:2619

Phase1 CAGE Peaks

	Short description
Mm9::chr11:100800621..100800633,-	p5@Stat3
Mm9::chr11:100800641..100800669,-	p3@Stat3
Mm9::chr2:75542032..75542048,-	p@chr2:75542032..75542048 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042755	eating behavior	0.0168739385306525
GO:0001659	thermoregulation	0.0168739385306525
GO:0001754	eye photoreceptor cell differentiation	0.0168739385306525
GO:0046530	photoreceptor cell differentiation	0.0168739385306525
GO:0007259	JAK-STAT cascade	0.0168739385306525
GO:0006953	acute-phase response	0.0168739385306525
GO:0042593	glucose homeostasis	0.0168739385306525
GO:0033500	carbohydrate homeostasis	0.0168739385306525
GO:0007631	feeding behavior	0.0182131400013392
GO:0048592	eye morphogenesis	0.0197227852955679
GO:0019221	cytokine and chemokine mediated signaling pathway	0.0197227852955679
GO:0040014	regulation of multicellular organism growth	0.0208915429427126
GO:0035264	multicellular organism growth	0.0226222033048308
GO:0002526	acute inflammatory response	0.0265161891195968
GO:0001654	eye development	0.0334264687083402
GO:0040008	regulation of growth	0.0445954089738673
GO:0016563	transcription activator activity	0.0477520981547717
GO:0007423	sensory organ development	0.0477520981547717
GO:0046983	protein dimerization activity	0.0477520981547717
GO:0006954	inflammatory response	0.0477520981547717
GO:0048878	chemical homeostasis	0.0477520981547717
GO:0007243	protein kinase cascade	0.0479921108858818

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br><br><br>

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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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