MCL coexpression mm9:1389: Difference between revisions
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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0.0336989752184957,0.0455894054315693,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0682179984609265,0,0,0,0.0448482436884352,0,0,0,0,0,0.0434877098916977,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0209679878844212,0.067899109889216,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.639243382371494,0.650640577508874,0.981120591583446,0.868308311097396,0.807441538864532,0.556005207165207,0,0,0,0,0,0,0,0,0,0,0.779579216172888,0,0,0,0,0,0,0,0.0514097768499148,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.654151030041435,1.44184080369063,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0398950534645112,0,0,0,0,0.0486868322374133,0.0394017081901728,0.0773548534010084,0,0.0424914383301275,0,0,0.0234910315133595,0,0,0,0.0147194505648231,0.0510354312356978,0,0.0316664407153844,0,1.1728342036219,0,0,0,0.177170830919231,0.203685621581279,0.311589133942676,0.197388711530769,0.2732433712351,0.652676027437114,1.00979318564265,1.00005593822209,1.16874368029199,1.2883720625474,1.0212517781227,0.852862647659203,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0288216590713588,0,0,0.061916064303354,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0662835200988411,0,0,0.0244872863598586,0.0616451109273545,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.027471976078474,0.330991708391442,0.050487679316216,0,0,0,0,0,0,0,0,0,0.050255708126026,0,0,0,0,0,0,0,0,0,0.024646902068351,0,0,0,0,0,0,0,0,0,0,0,0,0.106559150602475,0.279262439041853,0.0421752250554017,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0366471485294105,0.0871588832444397,0,0,0.0978461107777356,0.098117166361508,0,0.0388749848471105,0.051627820512194,0.0466475060481989,0,0.0238095886952444,0,0.074930558382725,0,0,0,0,0.0294684307081759,0.0569785733435272,0.017637724668944,0.0364791508700876,0,0.0798283833100081,0,0.0486884105045233,0.0408018333703219,0,0.0312791175364151,0.0383032227056179,0,0.0456455446387725,0.0422650922646472,0,0.0432851562487011,0 | |coexpression_dpi_cluster_scores_median=0,0,0,0,0,0.0336989752184957,0.0455894054315693,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0682179984609265,0,0,0,0.0448482436884352,0,0,0,0,0,0.0434877098916977,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0209679878844212,0.067899109889216,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.639243382371494,0.650640577508874,0.981120591583446,0.868308311097396,0.807441538864532,0.556005207165207,0,0,0,0,0,0,0,0,0,0,0.779579216172888,0,0,0,0,0,0,0,0.0514097768499148,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.654151030041435,1.44184080369063,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0398950534645112,0,0,0,0,0.0486868322374133,0.0394017081901728,0.0773548534010084,0,0.0424914383301275,0,0,0.0234910315133595,0,0,0,0.0147194505648231,0.0510354312356978,0,0.0316664407153844,0,1.1728342036219,0,0,0,0.177170830919231,0.203685621581279,0.311589133942676,0.197388711530769,0.2732433712351,0.652676027437114,1.00979318564265,1.00005593822209,1.16874368029199,1.2883720625474,1.0212517781227,0.852862647659203,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0288216590713588,0,0,0.061916064303354,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0662835200988411,0,0,0.0244872863598586,0.0616451109273545,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.027471976078474,0.330991708391442,0.050487679316216,0,0,0,0,0,0,0,0,0,0.050255708126026,0,0,0,0,0,0,0,0,0,0.024646902068351,0,0,0,0,0,0,0,0,0,0,0,0,0.106559150602475,0.279262439041853,0.0421752250554017,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0366471485294105,0.0871588832444397,0,0,0.0978461107777356,0.098117166361508,0,0.0388749848471105,0.051627820512194,0.0466475060481989,0,0.0238095886952444,0,0.074930558382725,0,0,0,0,0.0294684307081759,0.0569785733435272,0.017637724668944,0.0364791508700876,0,0.0798283833100081,0,0.0486884105045233,0.0408018333703219,0,0.0312791175364151,0.0383032227056179,0,0.0456455446387725,0.0422650922646472,0,0.0432851562487011,0 | ||
|gostat_on_MCL_coexpression=GO:0006958;complement activation, classical pathway;0.0330562534615398;12269!GO:0002455;humoral immune response mediated by circulating immunoglobulin;0.0330562534615398;12269!GO:0002541;activation of plasma proteins during acute inflammatory response;0.0330562534615398;12269!GO:0006956;complement activation;0.0330562534615398;12269!GO:0005923;tight junction;0.0330562534615398;56173!GO:0016064;immunoglobulin mediated immune response;0.0330562534615398;12269!GO:0019724;B cell mediated immunity;0.0330562534615398;12269!GO:0002526;acute inflammatory response;0.0330562534615398;12269!GO:0002253;activation of immune response;0.0330562534615398;12269!GO:0043296;apical junction complex;0.0330562534615398;56173!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0330562534615398;12269!GO:0045087;innate immune response;0.0330562534615398;12269!GO:0002250;adaptive immune response;0.0330562534615398;12269!GO:0016327;apicolateral plasma membrane;0.0330562534615398;56173!GO:0002449;lymphocyte mediated immunity;0.0330562534615398;12269!GO:0050778;positive regulation of immune response;0.0330562534615398;12269!GO:0002684;positive regulation of immune system process;0.0330562534615398;12269!GO:0002443;leukocyte mediated immunity;0.0330562534615398;12269!GO:0050776;regulation of immune response;0.0334689993924092;12269!GO:0002682;regulation of immune system process;0.0334689993924092;12269!GO:0051240;positive regulation of multicellular organismal process;0.0334689993924092;12269!GO:0002252;immune effector process;0.0355026203106886;12269!GO:0006959;humoral immune response;0.0355026203106886;12269!GO:0005911;intercellular junction;0.0375113022889046;56173!GO:0006954;inflammatory response;0.0498553802887337;12269! | |gostat_on_MCL_coexpression=GO:0006958;complement activation, classical pathway;0.0330562534615398;12269!GO:0002455;humoral immune response mediated by circulating immunoglobulin;0.0330562534615398;12269!GO:0002541;activation of plasma proteins during acute inflammatory response;0.0330562534615398;12269!GO:0006956;complement activation;0.0330562534615398;12269!GO:0005923;tight junction;0.0330562534615398;56173!GO:0016064;immunoglobulin mediated immune response;0.0330562534615398;12269!GO:0019724;B cell mediated immunity;0.0330562534615398;12269!GO:0002526;acute inflammatory response;0.0330562534615398;12269!GO:0002253;activation of immune response;0.0330562534615398;12269!GO:0043296;apical junction complex;0.0330562534615398;56173!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0330562534615398;12269!GO:0045087;innate immune response;0.0330562534615398;12269!GO:0002250;adaptive immune response;0.0330562534615398;12269!GO:0016327;apicolateral plasma membrane;0.0330562534615398;56173!GO:0002449;lymphocyte mediated immunity;0.0330562534615398;12269!GO:0050778;positive regulation of immune response;0.0330562534615398;12269!GO:0002684;positive regulation of immune system process;0.0330562534615398;12269!GO:0002443;leukocyte mediated immunity;0.0330562534615398;12269!GO:0050776;regulation of immune response;0.0334689993924092;12269!GO:0002682;regulation of immune system process;0.0334689993924092;12269!GO:0051240;positive regulation of multicellular organismal process;0.0334689993924092;12269!GO:0002252;immune effector process;0.0355026203106886;12269!GO:0006959;humoral immune response;0.0355026203106886;12269!GO:0005911;intercellular junction;0.0375113022889046;56173!GO:0006954;inflammatory response;0.0498553802887337;12269! | ||
|ontology_enrichment_celltype= | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0002107!1.01e-19!22;UBERON:0007499!1.01e-19!22;UBERON:0006925!1.01e-19!22;UBERON:0009497!1.01e-19!22;UBERON:0000015!1.01e-19!22;UBERON:0002423!1.01e-19!22;UBERON:0006235!1.01e-19!22;UBERON:0008835!1.01e-19!22;UBERON:0003894!1.01e-19!22;UBERON:0004161!1.01e-19!22;UBERON:0008836!1.01e-19!22;UBERON:0009854!1.35e-18!23;UBERON:0009856!1.35e-18!23;UBERON:0002365!1.27e-16!25;UBERON:0002330!1.27e-16!25;UBERON:0005256!2.77e-13!45;UBERON:0005172!1.87e-12!49;UBERON:0005173!1.87e-12!49;UBERON:0002417!1.87e-12!49;UBERON:0000916!1.87e-12!49;UBERON:0003104!3.52e-11!61;UBERON:0009142!3.52e-11!61;UBERON:0003914!3.31e-10!47;UBERON:0009569!2.25e-07!66 | |||
}} | }} | ||
Revision as of 16:48, 11 October 2012
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr16:93929757..93929773,- | p1@Cldn14 |
| Mm9::chr1:132544045..132544050,- | p@chr1:132544045..132544050 - |
| Mm9::chr1:132558130..132558141,- | p6@C4bp |
| Mm9::chr1:132558142..132558160,- | p5@C4bp |
| Mm9::chr8:108659842..108659853,+ | p@chr8:108659842..108659853 + |
| Mm9::chr9:48148735..48148751,- | p6@Fam55b |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0006958 | complement activation, classical pathway | 0.0330562534615398 |
| GO:0002455 | humoral immune response mediated by circulating immunoglobulin | 0.0330562534615398 |
| GO:0002541 | activation of plasma proteins during acute inflammatory response | 0.0330562534615398 |
| GO:0006956 | complement activation | 0.0330562534615398 |
| GO:0005923 | tight junction | 0.0330562534615398 |
| GO:0016064 | immunoglobulin mediated immune response | 0.0330562534615398 |
| GO:0019724 | B cell mediated immunity | 0.0330562534615398 |
| GO:0002526 | acute inflammatory response | 0.0330562534615398 |
| GO:0002253 | activation of immune response | 0.0330562534615398 |
| GO:0043296 | apical junction complex | 0.0330562534615398 |
| GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 0.0330562534615398 |
| GO:0045087 | innate immune response | 0.0330562534615398 |
| GO:0002250 | adaptive immune response | 0.0330562534615398 |
| GO:0016327 | apicolateral plasma membrane | 0.0330562534615398 |
| GO:0002449 | lymphocyte mediated immunity | 0.0330562534615398 |
| GO:0050778 | positive regulation of immune response | 0.0330562534615398 |
| GO:0002684 | positive regulation of immune system process | 0.0330562534615398 |
| GO:0002443 | leukocyte mediated immunity | 0.0330562534615398 |
| GO:0050776 | regulation of immune response | 0.0334689993924092 |
| GO:0002682 | regulation of immune system process | 0.0334689993924092 |
| GO:0051240 | positive regulation of multicellular organismal process | 0.0334689993924092 |
| GO:0002252 | immune effector process | 0.0355026203106886 |
| GO:0006959 | humoral immune response | 0.0355026203106886 |
| GO:0005911 | intercellular junction | 0.0375113022889046 |
| GO:0006954 | inflammatory response | 0.0498553802887337 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| liver | 1.01e-19 | 22 |
| epithelial sac | 1.01e-19 | 22 |
| digestive gland | 1.01e-19 | 22 |
| epithelium of foregut-midgut junction | 1.01e-19 | 22 |
| anatomical boundary | 1.01e-19 | 22 |
| hepatobiliary system | 1.01e-19 | 22 |
| foregut-midgut junction | 1.01e-19 | 22 |
| hepatic diverticulum | 1.01e-19 | 22 |
| liver primordium | 1.01e-19 | 22 |
| septum transversum | 1.01e-19 | 22 |
| liver bud | 1.01e-19 | 22 |
| digestive tract diverticulum | 1.35e-18 | 23 |
| sac | 1.35e-18 | 23 |
| exocrine gland | 1.27e-16 | 25 |
| exocrine system | 1.27e-16 | 25 |
| trunk mesenchyme | 2.77e-13 | 45 |
| abdomen element | 1.87e-12 | 49 |
| abdominal segment element | 1.87e-12 | 49 |
| abdominal segment of trunk | 1.87e-12 | 49 |
| abdomen | 1.87e-12 | 49 |
| mesenchyme | 3.52e-11 | 61 |
| entire embryonic mesenchyme | 3.52e-11 | 61 |
| epithelial tube | 3.31e-10 | 47 |
| subdivision of trunk | 2.25e-07 | 66 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
{{{tfbs_overrepresentation_jaspar}}} |
