MCL coexpression mm9:3147

Phase1 CAGE Peaks

	Short description
Mm9::chr18:50287865..50287921,+	p1@Hsd17b4
Mm9::chr4:40090401..40090477,+	p1@Aco1
Mm9::chr9:55056747..55056796,+	p1@Fbxo22

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0060009	Sertoli cell development	0.00802015991679228
GO:0016829	lyase activity	0.00802015991679228
GO:0060008	Sertoli cell differentiation	0.00802015991679228
GO:0030350	iron-responsive element binding	0.00802015991679228
GO:0003994	aconitate hydratase activity	0.00802015991679228
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	0.0133654684857832
GO:0005498	sterol carrier activity	0.0143193601837251
GO:0000038	very-long-chain fatty acid metabolic process	0.0150345043694134
GO:0006635	fatty acid beta-oxidation	0.0261125941469408
GO:0032934	sterol binding	0.0261125941469408
GO:0008584	male gonad development	0.0261125941469408
GO:0051539	4 iron, 4 sulfur cluster binding	0.0261125941469408
GO:0019395	fatty acid oxidation	0.0261125941469408
GO:0046546	development of primary male sexual characteristics	0.0261125941469408
GO:0055072	iron ion homeostasis	0.0261125941469408
GO:0006099	tricarboxylic acid cycle	0.0261125941469408
GO:0006879	cellular iron ion homeostasis	0.0261125941469408
GO:0046356	acetyl-CoA catabolic process	0.0261125941469408
GO:0009060	aerobic respiration	0.0261125941469408
GO:0046661	male sex differentiation	0.0261125941469408
GO:0009109	coenzyme catabolic process	0.0261125941469408
GO:0045333	cellular respiration	0.0261125941469408
GO:0003729	mRNA binding	0.0261125941469408
GO:0051187	cofactor catabolic process	0.0266899475954307
GO:0006084	acetyl-CoA metabolic process	0.0272207618157703
GO:0051536	iron-sulfur cluster binding	0.031860439234296
GO:0051540	metal cluster binding	0.031860439234296
GO:0005496	steroid binding	0.0335731150194027
GO:0016836	hydro-lyase activity	0.033791094855001
GO:0008406	gonad development	0.0339942505142106
GO:0048608	reproductive structure development	0.0341840166258144
GO:0045137	development of primary sexual characteristics	0.0357358465760238
GO:0016835	carbon-oxygen lyase activity	0.0357358465760238
GO:0015980	energy derivation by oxidation of organic compounds	0.0387850424476847
GO:0007548	sex differentiation	0.0416569334533002
GO:0003006	reproductive developmental process	0.0462140591944883
GO:0042579	microbody	0.0462140591944883
GO:0005777	peroxisome	0.0462140591944883
GO:0030005	cellular di-, tri-valent inorganic cation homeostasis	0.0485922714011397
GO:0055066	di-, tri-valent inorganic cation homeostasis	0.0488655484476814

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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