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MCL coexpression mm9:2917: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0008538;proteasome activator activity;1.26963764080105e-06;19188,19186!GO:0008537;proteasome activator complex;1.26963764080105e-06;19188,19186!GO:0019884;antigen processing and presentation of exogenous antigen;7.13296994123463e-05;19188,19186!GO:0005829;cytosol;7.33027846218437e-05;19171,19188,19186!GO:0019882;antigen processing and presentation;0.000269645944078079;19188,19186!GO:0044445;cytosolic part;0.000614570947289921;19188,19186!GO:0008047;enzyme activator activity;0.00243690941384157;19188,19186!GO:0043234;protein complex;0.00364705363700122;19171,19188,19186!GO:0032991;macromolecular complex;0.00648665598134676;19171,19188,19186!GO:0005839;proteasome core complex (sensu Eukaryota);0.0146625694870512;19171!GO:0004298;threonine endopeptidase activity;0.0147311104524437;19171!GO:0002376;immune system process;0.0157733780691099;19188,19186!GO:0000502;proteasome complex (sensu Eukaryota);0.0157733780691099;19171!GO:0044444;cytoplasmic part;0.0157733780691099;19171,19188,19186!
|gostat_on_MCL_coexpression=GO:0008538;proteasome activator activity;1.26963764080105e-06;19188,19186!GO:0008537;proteasome activator complex;1.26963764080105e-06;19188,19186!GO:0019884;antigen processing and presentation of exogenous antigen;7.13296994123463e-05;19188,19186!GO:0005829;cytosol;7.33027846218437e-05;19171,19188,19186!GO:0019882;antigen processing and presentation;0.000269645944078079;19188,19186!GO:0044445;cytosolic part;0.000614570947289921;19188,19186!GO:0008047;enzyme activator activity;0.00243690941384157;19188,19186!GO:0043234;protein complex;0.00364705363700122;19171,19188,19186!GO:0032991;macromolecular complex;0.00648665598134676;19171,19188,19186!GO:0005839;proteasome core complex (sensu Eukaryota);0.0146625694870512;19171!GO:0004298;threonine endopeptidase activity;0.0147311104524437;19171!GO:0002376;immune system process;0.0157733780691099;19188,19186!GO:0000502;proteasome complex (sensu Eukaryota);0.0157733780691099;19171!GO:0044444;cytoplasmic part;0.0157733780691099;19171,19188,19186!
}}
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Revision as of 13:20, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr14:56197281..56197376,+p1@Psme1
Mm9::chr14:56209755..56209806,-p1@Psme2
Mm9::chr8:108461946..108462034,-p1@Psmb10


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008538proteasome activator activity1.26963764080105e-06
GO:0008537proteasome activator complex1.26963764080105e-06
GO:0019884antigen processing and presentation of exogenous antigen7.13296994123463e-05
GO:0005829cytosol7.33027846218437e-05
GO:0019882antigen processing and presentation0.000269645944078079
GO:0044445cytosolic part0.000614570947289921
GO:0008047enzyme activator activity0.00243690941384157
GO:0043234protein complex0.00364705363700122
GO:0032991macromolecular complex0.00648665598134676
GO:0005839proteasome core complex (sensu Eukaryota)0.0146625694870512
GO:0004298threonine endopeptidase activity0.0147311104524437
GO:0002376immune system process0.0157733780691099
GO:0000502proteasome complex (sensu Eukaryota)0.0157733780691099
GO:0044444cytoplasmic part0.0157733780691099



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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